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List of works by Jaroslav Roh

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

scientific article published on 02 June 2014

2,6-Dihydroxybenzaldehyde Analogues of the Iron Chelator Salicylaldehyde Isonicotinoyl Hydrazone: Increased Hydrolytic Stability and Cytoprotective Activity against Oxidative Stress

scientific article published on 05 November 2018

A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor

scientific article

Amino acid derivatives as transdermal permeation enhancers

scientific article

Azaphthalocyanines with fused triazolo rings: formation of sterically stressed constitutional isomers

scientific article published on 23 March 2012

Ceramides in the Skin Lipid Membranes: Length Matters

scientific article published on 06 December 2013

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.

scientific article published on April 2016

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

scientific article published on 28 July 2017

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

scientific article published on 05 March 2016

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase

scientific article published on 22 August 2019

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

scientific article published on 8 August 2017

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

scientific article published on 21 August 2014

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

scientific article published on 14 June 2011

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

scientific article published on 10 October 2019

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

scientific article

Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.

scientific article published on 20 September 2017

Investigation of structure-activity relationships of dexrazoxane analogues reveals topoisomerase IIβ interaction as a prerequisite for effective protection against anthracycline cardiotoxicity

scientific article published on 06 April 2020

Metal-Cation Recognition in Water by a Tetrapyrazinoporphyrazine-Based Tweezer Receptor

scientific article published on 8 January 2016

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials

scientific article published on 01 March 2019

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.

scientific article published on 25 November 2015

Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart.

scientific article published on 22 December 2017

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

scientific article published on 21 November 2016

Scalable Synthesis of Human Ultralong Chain Ceramides

scientific article published on 19 October 2015

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats

scientific article published on 20 November 2013

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

scientific article published on 28 February 2017

Tetrazole regioisomers in the development of nitro group-containing antitubercular agents

article

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

scientific article published on 07 May 2014

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

scientific article published on 02 July 2014

Transdermal delivery and cutaneous targeting of antivirals using a penetration enhancer and lysolipid prodrugs

scientific article published on 22 November 2013

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study

scientific article published on 14 March 2019

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