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List of works by Bao-Liang Song

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

scientific article published on 01 June 2018

A special issue on 'Metabolism'

scientific article published on 01 January 2013

A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth.

scientific article published on 26 October 2013

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

scientific article published on 4 January 2017

Ablation of gp78 in liver improves hyperlipidemia and insulin resistance by inhibiting SREBP to decrease lipid biosynthesis

scientific article published on 01 August 2012

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

scientific article published on 12 September 2014

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

scientific article published on 23 October 2018

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.

scientific article published on 15 March 2017

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

scientific article published on 12 June 2017

Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities

scientific article published on 10 February 2020

Cholesterol transport through lysosome-peroxisome membrane contacts

scientific journal article

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

scientific article published on 17 January 2020

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

scientific article published in Nature Communications

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

scientific article published on 10 August 2020

Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing

scientific article published on 27 August 2019

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

scientific article

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis

scientific article published on 11 November 2020

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

scientific article

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

scientific article

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

scientific article

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

scientific article published on 06 May 2019

Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.

scientific article

Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice

scientific article published on 20 March 2020

Identification and characterization of NPC1L1 variants in Uygur and Kazakh with extreme low-density lipoprotein cholesterol.

scientific article published on 30 September 2016

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection

scientific article published on 22 April 2015

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

scientific article published on 27 December 2016

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

scientific article published on 08 November 2018

Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

scientific article

Measurement of Cholesterol Transfer from Lysosome to Peroxisome Using an In Vitro Reconstitution Assay

scientific article published on 01 January 2017

Mechanisms and regulation of cholesterol homeostasis

scientific article published on 17 December 2019

Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers

scientific article

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

scientific article published on 08 September 2019

Niemann-Pick C1-Like 1 and cholesterol uptake.

scientific article published on 28 March 2012

Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.

scientific article published on 29 June 2016

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

scientific article published on 27 August 2015

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

scientific article published on 20 January 2018

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

scientific article published on 14 July 2020

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

scientific article published in Nature Communications

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

scientific article published on 16 March 2016

Preparation of an anti-Cdx-2 antibody for analysis of different species Cdx-2 binding to acat2 promoter

scientific article (publication date: 2003)

Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface

scientific article

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

scientific article published on 26 January 2018

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

scientific article published on 13 February 2017

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

scientific article published on 05 November 2020

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

scientific article published on 19 July 2019

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

scientific article

Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.

scientific article published in May 2010

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.

scientific article published in June 2017

The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.

scientific article

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

scientific article

The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.

scientific article published on 15 December 2013

The clathrin adaptor proteins ARH, Dab2, and numb play distinct roles in Niemann-Pick C1-Like 1 versus low density lipoprotein receptor-mediated cholesterol uptake.

scientific article

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

scientific article published on 07 August 2018

The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner

scientific journal article

Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes.

scientific article

Ubiquitin ligases in cholesterol metabolism

scientific article

Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.

scientific article published on 16 April 2004

Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase

scientific article

[Effects of chrysophanol on expression of SREBPs and lipid metabolism in Huh-7 cells].

scientific article published in February 2015

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