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List of works by Yusuke Furukawa

A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons ⬇️

scientific article published on September 1, 1998

A novel missense mutation of ABCA1 in transmembrane alpha-helix in a Japanese patient with Tangier disease.

scientific article

A novel variant of acute myelomonocytic leukemia carrying t(3;12)(q26;p13) with characteristics of 3q21q26 syndrome.

scientific article published in June 1998

A simple semisolid subtraction method using carbodiimide-coated microplates

scientific article published on 01 July 2000

AMPK activation primes cytoplasmic translocation and autophagic degradation of the BCR-ABL protein in CML cells

scientific article published on 18 October 2020

Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).

scientific article

Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis.

scientific article published in September 2009

Abnormalities of the retinoblastoma susceptibility gene (RB) in hematologic malignancies

scientific article published on 01 June 1992

Activation of human monocyte functions by tumor necrosis factor: rapid priming for enhanced release of superoxide and erythrophagocytosis, but no direct triggering of superoxide release

scientific article published on 01 March 1996

Alkylating agents induce histone H3K18 hyperacetylation and potentiate HDAC inhibitor-mediated global histone acetylation and cytotoxicity in mantle cell lymphoma.

scientific article published on 13 December 2013

Alteration of the fragile histidine triad gene early in carcinogenesis: an update.

scientific article published on November 2003

Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL cell lines.

scientific article published on 13 December 2017

Antileukemic effect of interferon-alpha is mediated through down-modulation of E2F activity

scientific article published on 01 April 1997

Antitumor effect of beta2-microglobulin in leukemic cell-bearing mice via apoptosis-inducing activity: activation of caspase-3 and nuclear factor-kappaB

scientific article published on 01 June 2001

Apoptosis during HL-60 cell differentiation is closely related to a G0/G1 cell cycle arrest

scientific article published on 01 July 1995

Arf tumor suppressor disrupts the oncogenic positive feedback loop including c-Myc and DDX5.

scientific article published on 27 January 2014

BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia

scientific article

Bcl-x is a regulatory factor of apoptosis and differentiation in megakaryocytic lineage cells

scientific article published on 01 March 1998

Beta(2)-microglobulin identified as an apoptosis-inducing factor and its characterization

scientific article published on 01 October 1999

Bone marrow stromal cell-mediated degradation of CD20 leads to primary rituximab resistance in mantle cell lymphoma

scientific article published on 14 September 2020

CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.

scientific article published on February 2008

CMP-NeuAc:Gal beta 1-->4GlcNAc alpha 2-->6sialyltransferase catalyzes NeuAc transfer to glycolipids ⬇️

scientific article published on September 1, 1997

Cell adhesion-induced phosphorylation and inactivation of EZH2 confer drug resistance to acute myeloid leukemia cells

scientific article published on 28 November 2017

Cell cycle control during hematopoietic cell differentiation

scientific article published on September 1, 1997

Cell cycle control genes and hematopoietic cell differentiation.

scientific article

Cell cycle regulation of hematopoietic stem cells

scientific article published on 01 June 1998

Chloroquine induces basophilic differentiation of HL-60 cells.

scientific article published on April 1997

Cholesterol reduction and atherosclerosis inhibition by bezafibrate in low-density lipoprotein receptor knockout mice.

scientific article published in May 2008

Combination chemotherapy of carboplatin and cytosine arabinoside for high-risk leukemia: a pilot study.

scientific article

Components of DNA damage checkpoint pathway regulate UV exposure-dependent alterations of gene expression of FHIT and WWOX at chromosome fragile sites.

scientific article

Constitutive production of interleukin 1 by human monocytic leukemia cell line JOSK-I and the production mechanism.

scientific article

Conversion of human fibroblasts into multipotent cells by cell-penetrating peptides

scientific article published on 10 August 2019

Corrigendum to "Interferon-α repressed telomerase along with G1-accumulation of Daudi cells" [Cancer Letters 142 (1) (1999) 23-30].

scientific article published on 25 July 2016

Cytomegalovirus gastritis as an initial manifestation of a patient with adult T-cell leukemia

scientific article published on 01 January 1988

Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.

scientific article published on February 2007

Defective binding of IRFs to the initiator element of interleukin-1beta-converting enzyme (ICE) promoter in an interferon-resistant Daudi subline

scientific article published on 01 May 1999

Demonstration of interleukin-1 beta transcripts in acute myeloblastic leukemic cells by in situ hybridization

scientific article published on 01 July 1990

Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells

scientific journal article

Differential roles of E-type cyclins during transformation of murine E2F-1-deficient cells.

scientific article

Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats

scientific journal article

Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

scientific article published on March 2007

Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells.

scientific article published on June 2004

Effect of exogenous E2F-1 on the expression of common chromosome fragile site genes, FHIT and WWOX

scientific article

Epigenetic mechanisms of cell adhesion-mediated drug resistance in multiple myeloma.

scientific article

Epigenetic regulation of cell adhesion-mediated drug resistance acquisition in multiple myeloma.

scientific article

Eradication of Central Nervous System Leukemia of T-Cell Origin with a Brain-Permeable LSD1 Inhibitor

scientific article published on 05 December 2018

Establishment and characterization of four human monocytoid leukemia cell lines (JOSK-I, -S, -M and -K) with capabilities of monocyte-macrophage lineage differentiation and constitutive production of interleukin 1.

scientific article published in June 1986

Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

scientific article published on April 1990

Expression levels of histone deacetylases determine the cell fate of hematopoietic progenitors.

scientific article published on 07 September 2009

Failure of cdc2 promoter activation and G(2)/M transition by ANG II and AVP in vascular smooth muscle cells

scientific article published on 01 August 1999

HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells

scientific article published on August 5, 2010

Herbimycin A down-regulates messages of cyclin D1 and c-myc during erythroid differentiation of K562 cells

scientific article published on 01 December 1996

Heterogeneous expression of the product of the retinoblastoma susceptibility gene in primary human leukemia cells.

scientific article published in August 1991

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8 ⬇️

scientific article published on February 1, 2012

Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.

scientific article published in January 2006

Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding

scientific article

Human monocyte-endothelial cell interaction induces platelet-derived growth factor expression

scientific article published on 01 January 1998

Human monocyte-endothelial cell interaction induces synthesis of granulocyte-macrophage colony-stimulating factor

scientific article published on 01 March 1996

Hyperglycemia enhances VSMC proliferation with NF-kappaB activation by angiotensin II and E2F-1 augmentation by growth factors.

scientific article published in June 2002

Identification of novel p53-binding proteins by biomolecular interaction analysis combined with tandem mass spectrometry.

scientific article published in March 2003

Inactivation of ERK accelerates erythroid differentiation of K562 cells induced by herbimycin A and STI571 while activation of MEK1 interferes with it.

scientific article published on March 2004

Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis.

scientific article

Interleukin 1 production by monocytic leukemia cells and its possible role in coagulation abnormalities ⬇️

scientific article published on January 1, 1991

Interleukin-1 derived from human monocytic leukemia cell line JOSK-I acts as an autocrine growth factor

scientific article published on 01 August 1987

Interleukin-1 producing ability of leukaemia cells and its relationship to morphological diagnosis

scientific article published on 01 January 1987

Interleukin-3-associated ganglioside GD1a is induced independently of normal interleukin-3 receptor in murine myelogenous leukaemia NFS60 cells transfected with the interleukin-3 gene.

scientific article

Involvement of the tumor necrosis factor (TNF)/TNF receptor system in leukemic cell apoptosis induced by histone deacetylase inhibitor depsipeptide (FK228).

scientific article published in May 2005

Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells

scientific article published on 31 October 2019

Latexin regulates the abundance of multiple cellular proteins in hematopoietic stem cells.

scientific article published in March 2012

Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation

scientific article published on 01 September 2000

Lysine-specific demethylase 1 accelerates oncogenesis in p53 heterozygous mice via transcriptional repression of the residual Trp53 allele

scientific article published on 23 May 2019

Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells.

scientific article published on 8 January 2018

MSK1 activation in acute myeloid leukemia cells with FLT3 mutations.

scientific article published in April 2010

Modulation of E2F activity is linked to interferon-induced growth suppression of hematopoietic cells

scientific article published on 01 May 1997

Modulation of the erythropoietin-induced proliferative pathway by cAMP in vascular smooth muscle cells.

scientific article published in December 2002

Molecular basis of clonal evolution in multiple myeloma

scientific article published on 06 February 2020

Molecular pathogenesis of multiple myeloma.

scientific article published on 08 May 2015

Myelodysplastic syndrome in pregnancy with hematological improvement following delivery

scientific article published on 01 February 1988

Myeloma Cells are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex which Senses Lipopolysaccharide

scientific article published on 23 January 2018

Over-expression and amplification of the CDC2 gene in leukaemia cells

scientific article published on 01 May 1995

Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation.

scientific article published on 22 April 2015

Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

scientific article published on 01 July 2000

Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation: involvement of cyclin-dependent kinase inhibitor p21 in polyploidization.

scientific article published on June 1997

Promoter methylation confers kidney-specific expression of the Klotho gene

scientific article

Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repression of Notch1 in T-cell acute lymphoblastic leukemia

scientific article

Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies

scientific article (publication date: 2014)

Rad9 modulates the P21WAF1 pathway by direct association with p53.

scientific article

Rapid internalization of exogenous ganglioside GM3 and its metabolism to ceramide in human myelogenous leukemia HL-60 cells compared with control ganglioside GM1

scientific article published on 01 January 1997

Reduced histone H3K9 acetylation of clock genes and abnormal glucose metabolism in ob/ob mice.

scientific article

Regulation of EGF-induced tenascin-C by steroids in tenascin-C-non-producing human carcinoma cells

scientific article published on 01 November 1995

Regulatory effects of aggregated LDL on apoptosis during foam cell formation of human peripheral blood monocytes

scientific article published on 01 June 1997

Role of cyclins in cAMP inhibition of glomerular mesangial cell proliferation.

scientific article published in July 2004

Romidepsin overcomes cell adhesion-mediated drug resistance in multiple myeloma cells.

scientific article published on 12 December 2013

Schedule-dependent interaction between raltitrexed and 5-fluorouracil in human colon cancer cell lines in vitro

scientific article published on 01 January 2000

Schedule-dependent interactions between pemetrexed and cisplatin in human carcinoma cell lines in vitro.

scientific article published on January 2006

Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.

scientific article published in September 2002

Schedule-dependent synergism and antagonism between pemetrexed and paclitaxel in human carcinoma cell lines in vitro.

scientific article published on 31 August 2004

Serum Endocrine Fibroblast Growth Factors as Potential Biomarkers for Chronic Kidney Disease and Various Metabolic Dysfunctions in Aged Patients

scientific article published on 01 February 2020

Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins.

scientific article published on August 1990

Single glycosyltransferase, core 2 beta1-->6-N-acetylglucosaminyltransferase, regulates cell surface sialyl-Lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester.

scientific article published on October 1998

Soluble SLAMF7 is a predictive biomarker for elotuzumab therapy

scientific article published on 12 May 2020

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7

scientific article published on 29 July 2019

Soluble αKlotho as a candidate for the biomarker of aging

scientific article published on 14 October 2015

Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.

scientific article published on 4 December 2015

Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis

scientific article published on 22 May 2020

Stimulation of GATA-2 as a mechanism of hydrogen peroxide suppression in hypoxia-induced erythropoietin gene expression

scientific article published on 01 February 2001

Suitable drug combination with bortezomib for multiple myeloma under stroma-free conditions and in contact with fibronectin or bone marrow stromal cells.

scientific article published on 6 April 2014

Suppression of ARG kinase activity by STI571 induces cell cycle arrest through up-regulation of CDK inhibitor p18/INK4c.

scientific article

Tenascin-C induction by the diffusible factor epidermal growth factor in stromal-epithelial interactions.

scientific article

Tenascin-X expression in tumor cells and fibroblasts: glucocorticoids as negative regulators in fibroblasts

scientific journal article

The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations.

scientific article published on 10 December 2007

The expression of ST2 gene in helper T cells and the binding of ST2 protein to myeloma-derived RPMI8226 cells.

scientific article

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

scientific article published on 01 September 1989

The role of cell cycle control genes (the retinoblastoma susceptibility gene and cdc2 gene) in proliferation and differentiation of hematopoietic cells

scientific article published on 01 February 1992

The role of cellular transcription factor E2F in the regulation of cdc2 mRNA expression and cell cycle control of human hematopoietic cells.

scientific article published in October 1994

Three-dimensional matrix suppresses E2F-controlled gene expression in glomerular mesangial cells

scientific article published on 01 April 2000

Transactivation of RON receptor tyrosine kinase by interaction with PDGF receptor beta during steady-state growth of human mesangial cells.

scientific article published on 25 February 2009

Transcriptional activation of the cdc2 gene is associated with Fas-induced apoptosis of human hematopoietic cells

scientific article published on 01 November 1996

Transforming growth factor-beta inhibits phosphorylation of the retinoblastoma susceptibility gene product in human monocytic leukemia cell line JOSK-I.

scientific article published on August 1992

Treatment of myeloid leukemic cells with the phosphatase inhibitor okadaic acid induces cell cycle arrest at either G1/S or G2/M depending on dose

scientific article published on 01 March 1992

UDP-GlcNAc:Galbeta1-->3GalNAc (GlcNAc to GalNAc) beta1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines

scientific article published on 01 January 1999

Up-regulation of VLA-5 expression during monocytic differentiation and its role in negative control of the survival of peripheral blood monocytes

scientific article published on 01 March 1996

Vinculin Is Indispensable for Repopulation by Hematopoietic Stem Cells, Independent of Integrin Function ⬇️

scientific article published on July 27, 2010

[DNA methyltransferase inhibitors * histone deacetylase inhibitors]

[Essential thrombocythemia--a comparative study on polycythemia vera]

scientific article published on 01 March 1986

[High-dose cytosine arabinoside administration in the treatment of refractory leukemia]

scientific article published on 01 August 1985

[Involvement of innate immunity in the expansion of multiple myeloma cells and therapeutic intervention with lenalidomide]

scientific article published on 01 January 2018

[Mechanisms of action and clinical effectiveness of the newly approved anti-cancer drug bendamustine]

scientific article published on 01 July 2011

[Primary non-Hodgkin's lymphoma, small lymphocytic type, in the spleen complicating myelodysplastic syndrome]

scientific article published on 01 July 1988

[Remission induction failures in adult acute non-lymphocytic leukemia]

scientific article published in June 1985

[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia]

scientific article published on 01 March 1998

[Retrospective analysis on 21 patients with follicular lymphoma]

scientific article published on 01 January 1996

[The clinical effect of low-dose Ara-C in patients with refractory acute nonlymphocytic leukemia and myelodysplastic syndrome]

scientific article published on 01 April 1987

[The mechanisms of drug resistance via the interaction of myeloma cells with stromal cells]

scientific article published in January 2015

[Treatment of 71 adult acute lymphoblastic leukemia]

scientific article published on 01 September 1993

[Treatment of malignant lymphoma in Jichi Medical School Hospital. 3) Treatment of advanced bad-risk lymphoma with the M-CHOP regimen]

scientific article published on 01 June 1988

[Treatment of malignant lymphoma: 12 years' experience with 109 patients. 1). Treatment of Hodgkin's disease]

scientific article published on 01 September 1987

[Treatment of malignant lymphoma: 12 years' experience with 109 patients. 2). Treatment of non-Hodgkin's lymphoma]

scientific article published on 01 September 1987

[Tumor suppressor genes and their role in abnormal production of leukocytes (leukemogenesis)]

scientific article published on 01 May 1993

cdc2 gene expression at the G1 to S transition in human T lymphocytes

scientific article

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