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List of works by Christian H Brandts

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

scientific article

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

scientific article published on 4 June 2014

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling

scientific article

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function

scientific article

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

scientific article

Adjuvant therapy for resectable high-risk soft tissue sarcoma: feasibility and efficacy of a sandwich chemoradiotherapy strategy

scientific article published on 24 September 2011

Biglycan is a new high-affinity ligand for CD14 in macrophages

scientific article published on 17 May 2018

Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study.

scientific article published on 18 May 2017

Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis

scientific article published on 01 September 2018

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

scientific article published on 12 March 2019

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

scientific article published in November 2005

Curing of chloroquine-resistant malaria with clindamycin.

scientific article published on November 1993

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

scientific article published on 2 October 2017

Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient

scientific article published on 28 March 2017

Drug sensitivity of Plasmodium falciparum in Gabon. Activity correlations between various antimalarials.

scientific article published on September 1994

E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.

scientific article published on 4 September 2009

Effect of paracetamol on parasite clearance time in Plasmodium falciparum malaria.

scientific article

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

scientific article

Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study

scientific article

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

scientific article

Flt3-dependent transformation by inactivating c-Cbl mutations in AML

scientific article published on 19 April 2007

Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia

scientific article

IT behind a platform for Translational Cancer Research - concept and objectives.

scientific article published in January 2012

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial

scientific article published on 31 October 2016

Innovating the outreach of comprehensive cancer centers

scientific article published on 02 February 2019

Interferon-γ impairs proliferation of hematopoietic stem cells in mice

scientific article published on 13 March 2013

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

scientific article published on 14 October 2019

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

scientific article published in October 2000

Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

scientific article published on 29 November 2018

Malaria epidemiology in the province of Moyen Ogoov, Gabon.

scientific article

Minimized combinatorial CRISPR screens identify genetic interactions in autophagy

scientific article published on 01 June 2021

Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms

scientific article published in October 2002

New method to quantify erythrophagocytosis by autologous monocytes.

scientific article published in April 2007

Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.

scientific article published in September 2004

Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production.

scientific article published in November 1995

Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation.

scientific article published on May 2004

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

scientific article

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

scientific article

SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment

scientific article published on 28 July 2017

Selective Autophagy in Normal and Malignant Hematopoiesis

scientific article published on 28 June 2019

Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN)

scientific article published on 16 July 2020

Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial

scientific article published on 29 July 2013

Successful treatment of AIDS-associated, primary CNS lymphoma with rituximab- and methotrexate-based chemotherapy and autologous stem cell transplantation.

scientific article published on 20 January 2014

Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia

scientific article published on 07 December 2011

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

scientific article published on 9 September 2015

The dual role of tumor necrosis factor (TNF) during a malarial attack

scientific article published in July 1997

Topical transforming growth factor-beta3 in the prevention or alleviation of chemotherapy-induced oral mucositis in patients with lymphomas or solid tumors

scientific article published on 01 July 2001

Ubiquitination and selective autophagy

scientific article

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