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List of works by Angeles Martín-Requero

A megalin polymorphism associated with promoter activity and Alzheimer's disease risk.

scientific article published in June 2010

Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease.

scientific article

Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer's disease [amyloid precursor protein/presenilin 1 (PS1)].

scientific article published on 15 June 2012

Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients.

scientific article published on May 2005

Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia.

scientific article published on August 2003

Calmodulin levels in blood cells as a potential biomarker of Alzheimer's disease

scientific article

Cloning and functional characterization of the 5' regulatory region of the human mitochondrial glycerol-3-phosphate dehydrogenase gene. Lack of 3,5,3'-triiodothyronine responsiveness in adipose tissue.

scientific article

Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients

scientific article

Enhanced proliferation of lymphoblasts from patients with Alzheimer dementia associated with calmodulin-dependent activation of the na+/H+ exchanger.

scientific article published on April 2001

Familial Alzheimer's Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants

scientific article published on 19 September 2016

G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients.

scientific article published on 3 September 2014

Impaired protein kinase C activation is associated with decreased hepatic alpha 1-adrenoreceptor responsiveness in adrenalectomized rats

scientific article published on 01 February 1995

Increased Wnt Signaling and Reduced Viability in a Neuronal Model of Progranulin-Deficient Frontotemporal Lobar Degeneration.

scientific article published on 17 December 2015

Increasing progranulin levels and blockade of the ERK1/2 pathway: upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia.

scientific article

Interaction of oxamate with the gluconeogenic pathway in rat liver

scientific article published on 01 April 1986

Interrelationships between ureogenesis and gluconeogenesis in perfused rat liver

scientific article published on 01 October 1993

Lymphocytes in Alzheimer's disease pathology: Altered signaling pathways.

scientific article

On the mechanism of glucagon stimulation of hepatic gluconeogenesis

scientific article published on 01 July 1977

On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients.

scientific article published in November 2008

Oxidative Stress and Aberrant Cell Cycle in Alzheimer's Disease Lymphocytes: Diagnostic Prospects

scientific article

PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers

scientific article published on 16 October 2013

Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates.

scientific article

Progranulin Deficiency Reduces CDK4/6/pRb Activation and Survival of Human Neuroblastoma SH-SY5Y Cells.

scientific article

Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers

scientific article

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients

scientific article published on 20 July 2018

Reciprocal changes in gluconeogenesis and ureagenesis induced by fatty acid oxidation

scientific article published on 01 December 1993

Relationship between cellular energy production and rates of glucose utilization by lung cells

scientific article published on 01 October 1977

Role of endogenous fatty acids in the control of hepatic gluconeogenesis

scientific article published on 01 January 1992

Role of the adenylate system and glycolytic flux in the control of protein synthesis in isolated rat lung cells

scientific article published on 01 October 1982

Role of the state of reduction of the NAD system on the regulation of hepatic protein synthesis in the rat in vivo

scientific article published on 01 January 1982

Systematic evaluation of magnetic resonance imaging and spectroscopy techniques for imaging a transgenic model of Alzheimer's disease (AβPP/PS1).

scientific article published in January 2012

Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations

scientific article published on 03 January 2020

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

scientific article published on 30 April 2016

Targeting cyclin D3/CDK6 activity for treatment of Parkinson's disease

scientific article published on 15 March 2015

The cyclopentenone 15-deoxy-delta(12,14)-prostaglandin J2 inhibits G1/S transition and retinoblastoma protein phosphorylation in immortalized lymphocytes from Alzheimer's disease patients.

scientific article

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and Amyotrophic Lateral Sclerosis (ALS)

scientific article published on 06 July 2020