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List of works by Morgan H James

A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?

scientific article published on 24 December 2016

Activation of lateral hypothalamic group III metabotropic glutamate receptors suppresses cocaine-seeking following abstinence and normalizes drug-associated increases in excitatory drive to orexin/hypocretin cells

scientific article published on 22 September 2018

Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure

scientific article

Clinical staging: a necessary step in the development of improved animal models of mood disturbance?

scientific article published on 16 October 2013

Cocaine potentiates excitatory drive in the perifornical/lateral hypothalamus ⬇️

scientific article published on May 28, 2012

Cocaine- and Amphetamine-Regulated Transcript (CART) Signaling within the Paraventricular Thalamus Modulates Cocaine-Seeking Behaviour ⬇️

scientific article published on September 23, 2010

Commentary: "Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity".

scientific article published on 27 October 2015

Cued Reinstatement of Cocaine but Not Sucrose Seeking Is Dependent on Dopamine Signaling in Prelimbic Cortex and Is Associated with Recruitment of Prelimbic Neurons That Project to Contralateral Nucleus Accumbens Core.

scientific article published on 20 November 2017

Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats

scientific article published on 14 October 2018

Differential roles of medial prefrontal subregions in the regulation of drug seeking.

scientific article published on 18 December 2014

Do striatal push/pull circuits hold the key to compulsive, relapsing heroin addiction? : A Research Highlight on: Chemogenetic modulation of accumbens direct or indirect pathways bidirectionally alters reinstatement of heroin-seeking in high- but no

scientific article published on 23 January 2020

Electrophysiological characteristics of paraventricular thalamic (PVT) neurons in response to cocaine and cocaine- and amphetamine-regulated transcript (CART).

scientific article published on 22 August 2014

Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

scientific article

Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats

scientific article published on 07 August 2018

Intermittent self-administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system

scientific article published on 14 August 2020

Motivational activation: a unifying hypothesis of orexin/hypocretin function ⬇️

scientific article

New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway

scientific article published on 10 May 2017

Novelty preference does not predict trait cocaine behaviors in male rats

scientific article published in 2022

Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls

scientific article

Orexin-1 Receptor Signaling in Ventral Pallidum Regulates Motivation for the Opioid Remifentanil

scientific article published on 22 October 2019

Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking.

scientific article published on 29 March 2011

Orexin/Hypocretin, Central Amygdala, and Escalation of Cocaine Intake.

scientific article published in April 2017

Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner

scientific article published on 10 January 2016

Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats.

scientific article

Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil

scientific article published on 14 September 2019

Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking

scientific article published on August 2016

Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei.

scientific article published on 28 September 2011

Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum.

scientific article published on 12 May 2016

Repurposing the dual orexin receptor antagonist suvorexant for the treatment of opioid use disorder: why sleep on this any longer?

scientific article published on 27 January 2020

Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders.

scientific article published on 13 January 2017

Temporally specific miRNA expression patterns in the dorsal and ventral striatum of addiction-prone rats.

scientific article published on 13 June 2017

The Ventral Pallidum: Proposed Integrator of Positive and Negative Factors in Cocaine Abuse.

scientific article published on October 2016

The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand

scientific article published on 11 July 2019

The orexin-1 receptor antagonist SB-334867 reduces motivation, but not inhibitory control, in a rat stop signal task

scientific article published on 16 April 2019

The role of orexin-1 receptor signaling in demand for the opioid fentanyl

scientific article published on 21 May 2019

What about me…? The PVT: a role for the paraventricular thalamus (PVT) in drug-seeking behavior ⬇️

scientific article published on March 6, 2013

mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels.

scientific article

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