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List of works by James T Patterson

A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction

scientific article published on 16 January 2013

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

scientific article

A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1.

scientific article published on 4 November 2010

Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering

scientific article (publication date: 2014)

Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action.

scientific article published on 30 November 2010

Chemically generated IgG2 bispecific antibodies through disulfide bridging.

scientific article published on 8 July 2017

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity

scientific article published in May 2009

Functional association of the N-terminal residues with the central region in glucagon-related peptides.

scientific article published on 10 June 2011

Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells.

scientific article published on 16 April 2013

HIV-1 inactivation by nucleic acid aptamers.

scientific article

Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.

scientific article published on 26 September 2016

Improving the serum stability of site-specific antibody conjugates with sulfone linkers

scientific article

Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli.

scientific article

Melanocortin signaling in the CNS directly regulates circulating cholesterol

scientific article

PSMA-targeted bispecific Fab conjugates that engage T cells.

scientific article published on 6 October 2017

Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone

scientific article published on 19 February 2016

Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.

scientific article published on 10 July 2015

Site-selective labeling of a lysine residue in human serum albumin.

scientific article published on 4 September 2014

Template-directed ligation of tethered mononucleotides by t4 DNA ligase for kinase ribozyme selection

scientific article

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