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List of works by Menno de Winther

A disintegrin and metalloproteases: molecular scissors in angiogenesis, inflammation and atherosclerosis

scientific article published on 08 May 2012

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice

scientific article

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

scientific article published on 08 November 2007

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

scientific article published on 23 December 2020

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

scientific article published on 08 September 2013

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

scientific article published on 29 August 2020

Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.

scientific article published on 21 January 2014

Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies.

scientific article published on January 2014

Autopsy and Histological Analysis of the Transgenic Mouse

scientific article published on 01 January 2011

Autopsy and histologic analysis of the transgenic mouse

scientific article published on 01 January 2003

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

scientific article published on 19 May 2016

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

scientific article

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

scientific article published on 03 February 2014

Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells

article

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

scientific article published on 22 December 2011

Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development

scientific article (publication date: 2012)

Bone marrow transplantations to study gene function in hematopoietic cells

article

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

scientific article published on 03 February 2014

CD70 limits atherosclerosis and promotes macrophage function.

scientific article published on 27 October 2016

Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice.

scientific article

Centromeric and noncentromeric ADE2-selectable fragmentation vectors for yeast artificial chromosomes in AB1380.

scientific article published on June 1997

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

scientific article published on 07 January 2019

DARC matter(s) for inflammatory cells

scientific article published in February 2018

Dectin-1 deficiency does not affect atherosclerosis development in mice

scientific article published on 7 February 2015

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

scientific article

Defining tissue- and disease-associated macrophages using a transcriptome-based classification model

Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes

scientific article published on 30 June 2016

Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow

scientific article published on 26 January 2016

Dietary (1-->3), (1-->4)-beta-D-glucans from oat activate nuclear factor-kappaB in intestinal leukocytes and enterocytes from mice

Distribution of macrophage polarization markers in human atherosclerosis

scientific article published on 26 September 2012

Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study

scientific article

Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions

scientific article published on 2 May 2013

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis

scientific article

Epigenetic Regulation of Monocyte and Macrophage Function

scientific article published on 17 March 2016

Epigenetic mechanisms of macrophage activation in type 2 diabetes.

scientific article published on 3 September 2016

Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis

scientific article published on 21 May 2015

Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro

scientific article

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

scientific article published on 10 July 2017

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

scientific article published on 25 September 2003

Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice.

scientific article

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis.

scientific article published on 5 April 2017

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

scientific article

Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis

scientific article published on 30 January 2014

IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment.

scientific article published on 6 March 2015

Immune Modulation of Brown(ing) Adipose Tissue in Obesity.

scientific article published on 16 November 2016

Impact of cholesterol on proinflammatory monocyte production by the bone marrow

scientific article published in 2021

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency

scientific article

In memoriam: Marten Hofker (1956–2016)

Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.

scientific article

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

scientific article

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.

scientific article published on 14 March 2017

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.

scientific article

Interferons as Essential Modulators of Atherosclerosis

scientific article published on 07 May 2015

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

scientific article published on 10 March 2018

Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL.

scientific article published on 13 July 2006

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.

scientific article

Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model

scientific article

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

scientific article published on 23 October 2008

MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden

scientific article published on May 2015

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

scientific article published on 08 December 2020

Macrophage Heterogeneity: Relevance and Functional Implications in Atherosclerosis

scientific article published on 01 March 2010

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells

scientific article

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

scientific article published on 16 August 2013

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice.

scientific article published on 18 June 2009

Macrophage polarization: the epigenetic point of view

scientific article published on October 2014

Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice

article

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

scientific article

Macrophage subsets in atherosclerosis as defined by single-cell technologies

scientific article published on 31 January 2020

Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice.

scientific article published on 20 April 2009

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

scientific article published in December 2004

Marten Hofker (1956–2016)

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

scientific article published on 28 November 2015

MiR-92a

scientific article published on 01 January 2014

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

scientific article

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.

scientific article published on October 2016

Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages

scientific article published on 10 May 2008

Modulating liver inflammation: a crucial role for cholesterol

article published in 2008

Molecular pathways regulating macrophage polarization: implications for atherosclerosis

scientific article published on June 2012

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

scientific article published on 24 October 2017

Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

scientific article published on 7 February 2015

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques

scientific article

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

scientific article published on 01 August 2010

Myeloid interferon-γ receptor deficiency does not affect atherosclerosis in LDLR(-/-) mice.

scientific article

Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease.

scientific article

NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy

scientific article published on 26 April 2012

New mouse models for lipoprotein metabolism and atherosclerosis

scientific article

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

scientific article published on 29 January 2018

Nuclear factor kappa B signaling in macrophage function and atherogenesis.

scientific article

Nuclear factor kappaB signaling in atherogenesis.

scientific article

PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia

scientific article published on 01 May 2017

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages

scientific article published on 24 September 2014

Passive immunization with hypochlorite-oxLDL specific antibodies reduces plaque volume in LDL receptor-deficient mice

scientific article published on 16 July 2013

Perfluorohexane-loaded macrophages as a novel ultrasound contrast agent: a feasibility study.

scientific article published on 7 June 2008

Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss

scientific article published on 02 November 2019

Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols

article

Repressing the repressor: Ezh2 mediates macrophage activation

scientific article published on 24 April 2018

Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis

scientific article published on 16 September 2013

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

scientific article

Rupture of the atherosclerotic plaque: does a good animal model exist?

scientific article

Salsalate activates brown adipose tissue in mice

scientific article published on 4 December 2014

Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions

scientific article published on 6 June 2013

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

scientific article published on 15 September 2020

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

scientific article

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.

scientific article published on 9 July 2014

The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies

scientific article published in September 2009

The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses

scientific article

The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis

scientific article published on 28 February 2007

The role of phospholipases in lipid modification and atherosclerosis

scientific article

Transcriptional and epigenetic regulation of macrophages in atherosclerosis

scientific article published on 02 October 2019

Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling.

scientific article published on 19 April 2016

Tumor necrosis factor-alpha promotes atherosclerotic lesion progression in APOE*3-Leiden transgenic mice

scientific article

Type-I interferons in atherosclerosis

scientific article published on 01 January 2020

Wound administration of M2-polarized macrophages does not improve murine cutaneous healing responses.

scientific article

p55 Tumour necrosis factor receptor in bone marrow-derived cells promotes atherosclerosis development in low-density lipoprotein receptor knock-out mice

article

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