List of works - Lei Qiang

Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation.

scientific article published on 19 July 2017

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

scientific article (publication date: 24 January 2017)

Autophagy controls p38 activation to promote cell survival under genotoxic stress

scientific article published on 4 December 2012

Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

scientific article

Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

scientific article published on 21 September 2017

Autophagy positively regulates DNA damage recognition by nucleotide excision repair

scientific article

DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.

scientific article published on 18 November 2010

Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes.

scientific article published on 27 July 2016

Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response.

scientific article

Epidermal SIRT1 regulates inflammation, cell migration, and wound healing

scientific article published on 26 October 2017

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

scientific article published on 5 August 2011

Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge.

scientific article

MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

scientific article published on 04 March 2020

Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin

scientific article published on March 2014

Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

scientific article published on 4 January 2016

NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance.

scientific article published on 12 January 2017

Oroxylin A reverses hypoxia-induced cisplatin resistance through inhibiting HIF-1α mediated XPC transcription

scientific article published on 25 September 2020

Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway.

scientific article published on 6 May 2011

Phosphorylation of xeroderma pigmentosum group C regulates ultraviolet-induced DNA damage repair.

scientific article published on 6 April 2018

Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells.

scientific article published in October 2011

Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.

scientific article published on 23 May 2010

Recent Advances Targeting C-C chemokine receptor type 2 for Liver Diseases in Monocyte/Macrophage

scientific article published on 07 October 2020

Regulation of XPC deubiquitination by USP11 in repair of UV-induced DNA damage.

scientific article published on 29 October 2017

Regulation of cell proliferation and migration by p62 through stabilization of Twist1.

scientific article

Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.

scientific article

Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy

scientific article published on 21 September 2017

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

scientific article

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair.

scientific article published on 19 October 2015

Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner

scientific article

Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism.

scientific article published on June 2010

List of works by Lei Qiang

Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation.

Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer

Autophagy controls p38 activation to promote cell survival under genotoxic stress

Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

Autophagy positively regulates DNA damage recognition by nucleotide excision repair

DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.

Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes.

Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response.

Epidermal SIRT1 regulates inflammation, cell migration, and wound healing

HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway

Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge.

MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy

Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin

Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance.

Oroxylin A reverses hypoxia-induced cisplatin resistance through inhibiting HIF-1α mediated XPC transcription

Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway.

Phosphorylation of xeroderma pigmentosum group C regulates ultraviolet-induced DNA damage repair.

Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells.

Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.

Recent Advances Targeting C-C chemokine receptor type 2 for Liver Diseases in Monocyte/Macrophage

Regulation of XPC deubiquitination by USP11 in repair of UV-induced DNA damage.

Regulation of cell proliferation and migration by p62 through stabilization of Twist1.

Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.

Small molecule GL-V9 protects against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair.

Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner

Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism.