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List of works by Hiroshi Hashizume

A Prunus mume extract stimulated the proliferation and differentiation of osteoblastic MC3T3-E1 cells.

scientific article published on 7 October 2011

A clinical case of endoscopically assisted anterior screw fixation for the type II odontoid fracture

scientific article published on 01 March 2003

A new 3-dimensional computed tomography imaging method to diagnose extraforaminal stenosis at the lumbosacral junction.

scientific article

A new electrophysiological method for the diagnosis of extraforaminal stenosis at L5-s1

scientific article published on 08 April 2014

An experimental approach to spinal fusion using sintered bovine bone in a pig model

scientific article published on 01 April 2000

An outcome measure for patients with cervical myelopathy: the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ): an average score of healthy volunteers.

scientific article published on 07 December 2013

Association of Lumbar Spondylolisthesis With Low Back Pain and Symptomatic Lumbar Spinal Stenosis in a Population-based Cohort: The Wakayama Spine Study.

scientific article

Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population: the Wakayama Spine Study ⬇️

scientific article published on March 5, 2013

Augmentation of motor evoked potentials using multi-train transcranial electrical stimulation in intraoperative neurophysiologic monitoring during spinal surgery.

scientific article published on 16 February 2014

Can decompression surgery relieve low back pain in patients with lumbar spinal stenosis combined with degenerative lumbar scoliosis?

scientific article published on 24 April 2013

Central administration of methotrexate reduces mechanical allodynia in an animal model of radiculopathy/sciatica

scientific article published on 01 August 2000

Changes in the extracellular matrix on the surface of sintered bovine bone implanted in the femur of a rabbit: An immunohistochemical study ⬇️

scientific article published on January 1, 1998

Classification of High Intensity Zones of the Lumbar Spine and Their Association with Other Spinal MRI Phenotypes: The Wakayama Spine Study.

scientific article

Clinical outcomes after microendoscopic laminotomy for lumbar spinal stenosis: a 5-year follow-up study.

scientific article published on 24 October 2014

Cognitive impairment associated with locomotive syndrome in community-dwelling elderly women in Japan

scientific article published on 12 September 2017

Comparison of neuropathic pain induced by the application of normal and mechanically compressed nucleus pulposus to lumbar nerve roots in the rat

scientific article published on 01 May 2003

Consuming breakfast and exercising longer during high school increases bone mineral density in young adult men.

scientific article published on 22 December 2012

Cyclooxygenase-2 inhibitor SC-236 attenuates mechanical allodynia following nerve root injury in rats

scientific article published on 01 November 2000

Development and evaluation of a video exercise program for locomotive syndrome in the elderly

scientific article published on 30 March 2013

Development and evaluation of a video exercise program for locomotive syndrome in the elderly

Development of a support tool for the clinical diagnosis of symptomatic lumbar intra- and/or extra-foraminal stenosis.

scientific article

Differences in prevalence and associated factors between mild and severe vertebral fractures in Japanese men and women: the third survey of the ROAD study

scientific article published on 03 January 2019

Diffuse idiopathic skeletal hyperostosis is associated with lumbar spinal stenosis requiring surgery

scientific article published on 11 January 2018

Distinct degree of radiculopathy at different levels of peripheral nerve injury.

scientific article published on 26 April 2012

Early versus delayed kyphoplasty for thoracolumbar osteoporotic vertebral fractures: The effect of timing on clinical and radiographic outcomes and subsequent compression fractures

scientific article published on 30 July 2018

Effects of basic fibroblast growth factor on spontaneous resorption of herniated intervertebral discs. An experimental study in the rabbit

scientific article published on 01 May 1999

Effects of steroid and lipopolysaccharide on spontaneous resorption of herniated intervertebral discs. An experimental study in the rabbit

scientific article published on 01 April 1998

Efficacy of Novel Minimally Invasive Surgery Using Spinal Microendoscope For Treating Extraforaminal Stenosis at the Lumbosacral Junction ⬇️

scientific article published on July 1, 2012

Efficacy of Posterior Segmental Decompression Surgery for Pincer Mechanism in Cervical Spondylotic Myelopathy: A Retrospective Case-controlled Study Using Propensity Score Matching.

scientific article published on 17 July 2015

Endoscope-assisted spinal decompression surgery for lumbar spinal stenosis

scientific article published on 04 October 2013

Epidural injection of cyclooxygenase-2 inhibitor attenuates pain-related behavior following application of nucleus pulposus to the nerve root in the rat.

scientific article published in March 2002

Evaluation of carriers of bone morphogenetic protein for spinal fusion

scientific article published in April 2001

Experimental spinal fusion using sintered bovine bone coated with type I collagen and recombinant human bone morphogenetic protein-2

scientific article published on 01 September 1999

Factors associated with lumbar spinal stenosis in a large-scale, population-based cohort: The Wakayama Spine Study

scientific article published on 18 July 2018

Factory and construction work is associated with an increased risk of severe lumbar spinal stenosis on MRI: A case control analysis within the wakayama spine study

scientific article published on 14 February 2019

Histochemical demonstration of nitric oxide in herniated lumbar discs. A clinical and animal model study

scientific article published on 01 May 1997

Improved accuracy of diagnosis of lumbar intra and/or extra-foraminal stenosis by use of three-dimensional MR imaging: comparison with conventional MR imaging

scientific article published on 11 December 2014

In vivo patch-clamp analysis of the antinociceptive actions of TRPA1 activation in the spinal dorsal horn.

scientific article published on 21 April 2015

Japanese orthopaedic association back pain evaluation questionnaire (JOABPEQ) as an outcome measure for patients with low back pain: reference values in healthy volunteers.

scientific article

Japanese orthopaedic association cervical myelopathy evaluation questionnaire (JOACMEQ): Part 5. Determination of responsiveness

scientific article published on 29 September 2018

Locomotive syndrome is associated with body composition and cardiometabolic disorders in elderly Japanese women

scientific article

Long-term survival case of malignant glomus tumor mimicking "dumbbell-shaped" neurogenic tumor.

scientific article published on 15 July 2016

Lumbar sagittal balance influences the clinical outcome after decompression and posterolateral spinal fusion for degenerative lumbar spondylolisthesis.

scientific article

MRI-defined paraspinal muscle morphology in Japanese population: The Wakayama Spine Study

scientific article published on 8 November 2017

Mechanical compression of the lumbar nerve root alters pain-related behaviors induced by the nucleus pulposus in the rat

scientific article published on 01 March 2000

Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study

scientific article published on 3 February 2016

Microendoscopic Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis: The Influence of Spondylolisthesis Stage (Disc Height and Static and Dynamic Translation) on Clinical Outcomes

scientific article published on 01 February 2019

Microendoscopic laminotomy versus conventional laminoplasty for cervical spondylotic myelopathy: 5-year follow-up study

scientific article published on 14 July 2017

Minimally invasive decompression surgery for lumbar spinal stenosis with degenerative scoliosis: Predictive factors of radiographic and clinical outcomes

scientific article published in February 2017

Minimally invasive spinal decompression for degenerative lumbar spondylolisthesis and stenosis maintains stability and may avoid the need for fusion

scientific article published on 01 April 2018

Osteogenic protein-1 (osteogenic protein-1/bone morphogenetic protein-7) inhibits degeneration and pain-related behavior induced by chronically compressed nucleus pulposus in the rat.

scientific article published in September 2005

Pathomechanism of pain-related behavior produced by allografts of intervertebral disc in the rat

scientific article published on 01 September 1996

Physical Performance Measures Associated With Locomotive Syndrome in Middle-Aged and Older Japanese Women.

scientific article

Physical performance decreases in the early stage of cervical myelopathy before the myelopathic signs appear: the Wakayama Spine Study

scientific article published on 07 February 2019

Possible mechanism of painful radiculopathy in lumbar disc herniation

scientific article published on 01 June 1998

Posterior endoscopic surgery for lumbar disc herniation with contralateral symptoms - a report of two cases

scientific article published on 01 October 2006

Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study.

scientific article

Prevalence and progression of radiographic ossification of the posterior longitudinal ligament and associated factors in the Japanese population: a 3-year follow-up of the ROAD study.

scientific article published on 22 August 2013

Prevalence of Facet Effusion and Its Relationship with Lumbar Spondylolisthesis and Low Back Pain: The Wakayama Spine Study

scientific article published on 31 December 2019

Prevalence of cervical cord compression and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study.

scientific article

Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) of the whole spine and its association with lumbar spondylosis and knee osteoarthritis: the ROAD study.

scientific article

Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama Spine Study

scientific article published on 10 July 2012

Progression, incidence, and risk factors for intervertebral disc degeneration in a longitudinal population-based cohort: the Wakayama Spine Study

scientific article published on 12 January 2017

Quantification of the proportion of motor neurons recruited by transcranial electrical stimulation during intraoperative motor evoked potential monitoring.

scientific article published on 8 June 2013

Radiographic natural course of lumbar degenerative spondylolisthesis and its risk factors related to the progression and onset in a 15-year community-based cohort study: the Miyama study.

scientific article published on 21 August 2015

Response to "Revisiting the nomenclature and grading schemes for disc degeneration: issues to be solved".

scientific article

Safety of epidural administration of Osteogenic Protein-1 (OP-1/BMP-7): behavioral and macroscopic observation

scientific article published on 01 June 2007

Sagittal spino-pelvic alignment in adults: The Wakayama Spine Study.

scientific article

Sarpogrelate hydrochloride, a 5-HT2A receptor antagonist, attenuates neurogenic pain induced by nucleus pulposus in rats.

scientific article published on February 2007

Serum levels of matrix metalloproteinase-3 and autoantibodies related to rheumatoid arthritis in the general Japanese population and their association with osteoporosis and osteoarthritis: the ROAD study.

scientific article published in April 2017

Skipping breakfast and less exercise are risk factors for bone loss in young Japanese adults: a 3-year follow-up study.

scientific article published on 20 September 2013

Spinal Endoscopy for Delayed-Onset Lumbar Radiculopathy Resulting from Foraminal Stenosis after Osteoporotic Vertebral Fracture: A Case Report of a New Surgical Strategy

Spinal glial activation and cytokine expression after lumbar root injury in the rat

scientific article published on 01 May 2000

The Association between the Cross-Sectional Area of the Dural Sac and Low Back Pain in a Large Population: The Wakayama Spine Study

scientific article

The Relationship between Locomotive Syndrome and Depression in Community-Dwelling Elderly People

scientific article

The association of combination of disc degeneration, end plate signal change, and Schmorl node with low back pain in a large population study: the Wakayama Spine Study

scientific article published on 27 November 2014

The effects of bone morphogenetic protein and basic fibroblast growth factor on cultured mesenchymal stem cells for spine fusion

scientific article published on 01 May 2007

The prevalence of cervical myelopathy among subjects with narrow cervical spinal canal in a population-based magnetic resonance imaging study: the Wakayama Spine Study

scientific article published on 05 April 2014

The prevalence of tandem spinal stenosis and its characteristics in a population-based MRI study: The Wakayama Spine Study

scientific article

The role of phospholipase A2 and nitric oxide in pain-related behavior produced by an allograft of intervertebral disc material to the sciatic nerve of the rat

scientific article published on 01 May 1997

The use of cultured bone marrow cells in type I collagen gel and porous hydroxyapatite for posterolateral lumbar spine fusion.

scientific article published in May 2005

The use of sintered bone in spinal surgery ⬇️

scientific article published on October 1, 2001

Verification of the sensitivity of functional scores for treatment results - Substantial clinical benefit thresholds for the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ).

scientific article published on 29 March 2017

[Spinal stenosis]

scientific article published on 01 October 2014

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