List of works - Raffael Schaffrath

Collaboration of tRNA modifications and elongation factor eEF1A in decoding and nonsense suppression

scientific article published in Scientific Reports

Combined tRNA modification defects impair protein homeostasis and synthesis of the yeast prion protein Rnq1.

scientific article published in January 2017

Cooperativity between different tRNA modifications and their modification pathways

scientific article published on 5 December 2017

Cryo-EM structures of the human Elongator complex at work

scientific article published in 2024

Diphthamide-deficiency syndrome: a novel human developmental disorder and ribosomopathy

scientific article published on 23 June 2020

Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-Canonical Cofactor Motifs with Tandem Cysteines

scientific article published in 2024

Glutaredoxin GRXS17 Associates with the Cytosolic Iron-Sulfur Cluster Assembly Pathway.

scientific article published on 8 August 2016

Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast

scientific article published in PLoS ONE

Independent suppression of ribosomal +1 frameshifts by different tRNA anticodon loop modifications.

scientific article

Induction of protein aggregation and starvation response by tRNA modification defects

scientific article published on 29 August 2020

Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator.

scientific article

Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast

scientific article published on 18 February 2020

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

scientific article published on 19 April 2018

Protein Phosphatase Sit4 Affects Lipid Droplet Synthesis and Soraphen A Resistance Independent of Its Role in Regulating Elongator Dependent tRNA Modification

scientific article published on 11 July 2018

Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer

article

Unfolded Protein Response Suppression in Yeast by Loss of tRNA Modifications

scientific article published on 23 October 2018

Use of a Yeast TRNase Killer Toxin to Diagnose Kti12 Motifs Required for TRNA Modification by Elongator

Use of a Yeast tRNase Killer Toxin to Diagnose Kti12 Motifs Required for tRNA Modification by Elongator.

scientific article published on 5 September 2017

Wobble uridine modifications-a reason to live, a reason to die?!

scientific article published on 23 February 2017

List of works by Raffael Schaffrath