List of works - Alba Casellas

AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance

scientific article published on 16 November 2016

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

scientific article

AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease.

scientific article published on October 2014

ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.

scientific article published on 3 May 2016

Altered glucose-stimulated insulin secretion in a mouse line with activated polyamine catabolism

scientific article published on 18 December 2011

Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta.

scientific article published in May 2000

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

scientific article

FGF21 gene therapy as treatment for obesity and insulin resistance

article

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

scientific article

Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

scientific article published on 21 December 2015

In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9.

scientific article published on 11 February 2011

Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance

scientific article

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

scientific article published on April 2004

Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

scientific article published on 13 May 2015

Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

scientific article published on March 2000

Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension

scientific article published on 01 February 2019

Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass.

scientific article published on 6 September 2012

Vitamin D Receptor overexpression in β-cells ameliorates diabetes in mice

scientific article published on 21 February 2020

List of works by Alba Casellas

AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice.

AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease.

ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.

Altered glucose-stimulated insulin secretion in a mouse line with activated polyamine catabolism

Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta.

Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

FGF21 gene therapy as treatment for obesity and insulin resistance

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

In vivo genetic engineering of murine pancreatic beta cells mediated by single-stranded adeno-associated viral vectors of serotypes 6, 8 and 9.

Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance

Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease.

Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage

Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension

Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass.

Vitamin D Receptor overexpression in β-cells ameliorates diabetes in mice