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List of works by David J Evans

3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88

scientific article (publication date: 2011)

A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with Pseudomonas aeruginosa

scientific article published on 12 November 2018

Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion.

scientific article published in September 2005

Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence.

scientific article published on 9 August 2011

Clearance of Pseudomonas aeruginosa from a healthy ocular surface involves surfactant protein D and is compromised by bacterial elastase in a murine null-infection model.

scientific article published on 6 April 2009

Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model.

scientific article published in September 2003

Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa

scientific article

Corneal surface glycosylation is modulated by IL-1R and Pseudomonas aeruginosa challenge but is insufficient for inhibiting bacterial binding.

scientific article published on 21 February 2017

Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones

scientific article

DMBT1 inhibition of Pseudomonas aeruginosa twitching motility involves its N-glycosylation and cannot be conferred by the Scavenger Receptor Cysteine-Rich bacteria-binding peptide domain

scientific article published on 11 September 2019

Dynamics of Pseudomonas aeruginosa association with anionic hydrogel surfaces in the presence of aqueous divalent-cation salts.

scientific article published on 13 June 2011

Dynamics of flagellum- and pilus-mediated association of Pseudomonas aeruginosa with contact lens surfaces.

scientific article

Epithelial cell lysates induce ExoS expression and secretion by Pseudomonas aeruginosa

scientific article published on 01 April 2018

Exotoxin S secreted by internalized Pseudomonas aeruginosa delays lytic host cell death

scientific article published on 07 February 2022

Exposure of human corneal epithelial cells to contact lenses in vitro suppresses the upregulation of human beta-defensin-2 in response to antigens of Pseudomonas aeruginosa.

scientific article published on 14 April 2007

Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa.

scientific article

Factors Impacting Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal ⬇️

scientific article published on March 14, 2011

Human Tear Fluid Reduces Culturability of Contact Lens-Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence-Associated Type III Secretion System.

scientific article published on 23 September 2016

Human tear fluid protects against Pseudomonas aeruginosa keratitis in a murine experimental model.

scientific article published on 26 February 2007

IL-1R and MyD88 Contribute to the Absence of a Bacterial Microbiome on the Healthy Murine Cornea.

scientific article published on 29 May 2018

Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection

scientific article published on 19 October 2018

MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2.

scientific article

Microbial keratitis: could contact lens material affect disease pathogenesis?

scientific article published on January 2013

Modulation of epithelial immunity by mucosal fluid.

scientific article published on 14 June 2011

Mucosal fluid glycoprotein DMBT1 suppresses twitching motility and virulence of the opportunistic pathogen Pseudomonas aeruginosa.

scientific article

Mutation of csk, encoding the C-terminal Src kinase, reduces Pseudomonas aeruginosa internalization by mammalian cells and enhances bacterial cytotoxicity.

scientific article published on September 2002

Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity.

scientific article published on 29 August 2007

Pathogenesis of contact lens-associated microbial keratitis

scientific article

Possible involvement of the division cycle in dispersal of Escherichia coli from biofilms.

scientific article published on March 1990

Pseudomonas aeruginosa Outer Membrane Vesicles Triggered by Human Mucosal Fluid and Lysozyme Can Prime Host Tissue Surfaces for Bacterial Adhesion.

scientific article published on 03 June 2016

Pseudomonas aeruginosa Survival at Posterior Contact Lens Surfaces after Daily Wear.

scientific article

Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility

scientific article

Pseudomonas aeruginosa strains with lipopolysaccharide defects exhibit reduced intracellular viability after invasion of corneal epithelial cells.

scientific article

Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells

scientific article

Pseudomonas aeruginosa-induced bleb-niche formation in epithelial cells is independent of actinomyosin contraction and enhanced by loss of cystic fibrosis transmembrane-conductance regulator osmoregulatory function

scientific article

Quantification of Bacterial Twitching Motility in Dense Colonies Using Transmitted Light Microscopy and Computational Image Analysis.

scientific article

Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model.

scientific article published in December 2003

Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal

scientific journal article

Role of the corneal epithelial basement membrane in ocular defense against Pseudomonas aeruginosa.

scientific article published on 08 June 2009

Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease.

scientific article

Susceptibility of Pseudomonas aeruginosa and Escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate

scientific article published on 01 February 1991

Susceptibility of bacterial biofilms to tobramycin: role of specific growth rate and phase in the division cycle

scientific article published on 01 April 1990

The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells.

scientific article

The Impact of ExoS on Pseudomonas aeruginosa Internalization by Epithelial Cells Is Independent of fleQ and Correlates with Bistability of Type Three Secretion System Gene Expression.

scientific article published in May 2018

The impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis.

scientific article

The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibility

scientific article

The rfb locus from Pseudomonas aeruginosa strain PA103 promotes the expression of O antigen by both LPS-rough and LPS-smooth isolates from cystic fibrosis patients.

scientific article

Traversal of Multilayered Corneal Epithelia by CytotoxicPseudomonas aeruginosaRequires the Phospholipase Domain of ExoU ⬇️

scientific article published on January 25, 2012

Type IV Pili Can Mediate Bacterial Motility within Epithelial Cells

scientific article published on 20 August 2019

Why does the healthy cornea resist Pseudomonas aeruginosa infection?

scientific article published on 17 April 2013

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