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List of works by Brent Holmes

AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation

scientific article

Conditional astroglial Rictor overexpression induces malignant glioma in mice

scientific article

Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma

scientific article published on 11 May 2016

Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamy

scientific article

Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness

scientific article published on 21 May 2015

Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress

scientific journal article

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.

scientific article

Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress.

scientific article published on 11 May 2015

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.

scientific article published on 23 October 2017

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