List of works - Francesco Peri

"Endotoxin, TLR4 signaling and beyond"

scientific article published on 11 September 2014

A highly convergent approach to O- and N-linked glycopeptide analogues

scientific article published on 01 August 1999

A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development

scientific article published on 8 August 2015

Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling

scientific article

Carbohydrate-based bioactive compounds for medicinal chemistry applications.

scientific article published on January 2011

Chemistry of lipid A: at the heart of innate immunity.

scientific article

Chemoselective Neoglycosylation

scientific article published on 01 January 2007

Chemoselective ligation in glycochemistry.

scientific article published on 14 November 2003

Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: new multivalent galectin-3 ligands

scientific article published on 23 July 2014

Co-administration of Antimicrobial Peptides (AMPs) EnhancesToll-like Receptor 4 (TLR4) Antagonist Activity of a Synthetic Glycolipid.

scientific article published on 19 December 2017

Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor ⬇️

scientific article published on April 1, 2003

Design and characterization of a new class of inhibitors of ras activation

scientific article

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

scientific article published on October 2005

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

scientific article

Dye-sensitized photocatalytic hydrogen production: distinct activity in a glucose derivative of a phenothiazine dye

scientific article published on 01 May 2016

Evidence of a specific interaction between new synthetic antisepsis agents and CD14.

scientific article

Extending chemoselective ligation to sugar chemistry: convergent assembly of bioactive neoglycoconjugates.

scientific article published on November 2003

First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand.

scientific article published on 30 May 2009

Functional characterization of E. coli LptC: interaction with LPS and a synthetic ligand.

scientific article published on March 2014

Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice.

scientific article

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

scientific article published on 13 August 2007

Glycoconjugate and oligosaccharide mimetics by chemoselective ligation

Glycoconjugates in cancer therapy.

scientific article published on January 2008

Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties.

scientific article published on 19 February 2016

Inhibition of lipid a stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides

scientific article published on 01 January 2007

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

scientific article

Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic.

scientific article

Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles.

scientific article published on 14 June 2014

NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes

scientific article published on 15 September 2014

Novel Tn antigen-containing neoglycopeptides: synthesis and evaluation as anti tumor vaccines.

scientific article published in May 2002

Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

scientific article

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties

scientific article published in Scientific Reports

Polycyclic scaffolds from fructose

Recent advances on Toll-like receptor 4 modulation: new therapeutic perspectives

scientific article published on 30 January 2018

SYNTHESIS OF IMINO-C-DISACCHARIDES RELATED TO SUCROSE1

Solution and solid-phase chemoselective synthesis of (1-6)-amino(methoxy) di- and trisaccharide analogues

scientific article published on 01 July 2002

Stereoselective synthesis of α-C-glycosides of N-acetylgalactosamine

article published in 2000

Structural characterization of aerogels derived from enzymatically oxidized galactomannans of fenugreek, sesbania and guar gums

scientific article published on 03 December 2018

Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108

scientific article published on 08 August 2018

Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.

scientific article published in March 2018

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

scientific article published on March 2010

Sugar-based inhibitors of Ras activation: biological activity and identification of Ras-inhibitor binding interface.

scientific article

Synthesis and biological evaluation of an anticancer vaccine containing the C-glycoside analogue of the Tn epitope.

scientific article published on May 2001

Synthesis and biological evaluation of novel lipid A antagonists.

scientific article

Synthesis and conformational analysis of novel N(OCH3)-linked disaccharide analogues.

scientific article published in March 2004

Synthesis of Imino Sugar Scaffolds for the Generation of Glycosidase Inhibitor Libraries

article by Barbara La Ferla et al published June 2004 in European Journal of Organic Chemistry

Synthesis of the New Cyanine-Labeled Bacterial Lipooligosaccharides for Intracellular Imaging and in Vitro Microscopy Studies

scientific article published on 11 June 2019

Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model.

scientific article

TLR4 Signaling Pathway Modulators as Potential Therapeutics in Inflammation and Sepsis

scientific article published on 4 October 2017

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.

scientific article published on 20 January 2017

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling

scientific article published on 3 November 2017

The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

scientific article published on 12 September 2018

Toll-like Receptor 4-Induced Glycolytic Burst in Human Monocyte-Derived Dendritic Cells Results from p38-Dependent Stabilization of HIF-1α and Increased Hexokinase II Expression

scientific article published on 23 July 2018

Toll-like receptor 4 (TLR4) modulation by synthetic and natural compounds: an update.

scientific article

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation

scientific article published on 15 February 2018

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.

scientific article published on 9 November 2010

List of works by Francesco Peri

"Endotoxin, TLR4 signaling and beyond"

A highly convergent approach to O- and N-linked glycopeptide analogues

A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development

Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling

Carbohydrate-based bioactive compounds for medicinal chemistry applications.

Chemistry of lipid A: at the heart of innate immunity.

Chemoselective Neoglycosylation

Chemoselective ligation in glycochemistry.

Clicked and long spaced galactosyl- and lactosylcalix[4]arenes: new multivalent galectin-3 ligands

Co-administration of Antimicrobial Peptides (AMPs) EnhancesToll-like Receptor 4 (TLR4) Antagonist Activity of a Synthetic Glycolipid.

Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor ⬇️

Design and characterization of a new class of inhibitors of ras activation

Design, synthesis and biological evaluation of sugar-derived Ras inhibitors

Design, synthesis, and biological evaluation of levoglucosenone-derived ras activation inhibitors.

Dye-sensitized photocatalytic hydrogen production: distinct activity in a glucose derivative of a phenothiazine dye

Evidence of a specific interaction between new synthetic antisepsis agents and CD14.

Extending chemoselective ligation to sugar chemistry: convergent assembly of bioactive neoglycoconjugates.

First experimental identification of Ras-inhibitor binding interface using a water-soluble Ras ligand.

Functional characterization of E. coli LptC: interaction with LPS and a synthetic ligand.

Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice.

Glucose-Derived Ras Pathway Inhibitors: Evidence of Ras–Ligand Binding and Ras–GEF (Cdc25) Interaction Inhibition

Glycoconjugate and oligosaccharide mimetics by chemoselective ligation

Glycoconjugates in cancer therapy.

Glycolipid-based TLR4 Modulators and Fluorescent Probes: Rational Design, Synthesis, and Biological Properties.

Inhibition of lipid a stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic.

Molecular simplification of lipid A structure: TLR4-modulating cationic and anionic amphiphiles.

NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes

Novel Tn antigen-containing neoglycopeptides: synthesis and evaluation as anti tumor vaccines.

Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties

Polycyclic scaffolds from fructose

Recent advances on Toll-like receptor 4 modulation: new therapeutic perspectives

SYNTHESIS OF IMINO-C-DISACCHARIDES RELATED TO SUCROSE1

Solution and solid-phase chemoselective synthesis of (1-6)-amino(methoxy) di- and trisaccharide analogues

Stereoselective synthesis of α-C-glycosides of N-acetylgalactosamine

Structural characterization of aerogels derived from enzymatically oxidized galactomannans of fenugreek, sesbania and guar gums

Structure and inflammatory activity of the LPS isolated from Acetobacter pasteurianus CIP103108

Structure-Activity Relationship in Monosaccharide-Based Toll-Like Receptor 4 (TLR4) Antagonists.

Structure-activity studies on arylamides and arysulfonamides Ras inhibitors

Sugar-based inhibitors of Ras activation: biological activity and identification of Ras-inhibitor binding interface.

Synthesis and biological evaluation of an anticancer vaccine containing the C-glycoside analogue of the Tn epitope.

Synthesis and biological evaluation of novel lipid A antagonists.

Synthesis and conformational analysis of novel N(OCH3)-linked disaccharide analogues.

Synthesis of Imino Sugar Scaffolds for the Generation of Glycosidase Inhibitor Libraries

Synthesis of the New Cyanine-Labeled Bacterial Lipooligosaccharides for Intracellular Imaging and in Vitro Microscopy Studies

Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model.

TLR4 Signaling Pathway Modulators as Potential Therapeutics in Inflammation and Sepsis

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling

The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

Toll-like Receptor 4-Induced Glycolytic Burst in Human Monocyte-Derived Dendritic Cells Results from p38-Dependent Stabilization of HIF-1α and Increased Hexokinase II Expression

Toll-like receptor 4 (TLR4) modulation by synthetic and natural compounds: an update.

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.