List of works - Wieslawa Widlak

17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells

scientific article published on 11 October 2019

A 252 bp upstream region of the rat spermatocyte-specific hst70 gene is sufficient to promote expression of the hst70-CAT hybrid gene in testis and brain of transgenic mice

scientific article published on 01 November 1995

Active heat shock transcription factor 1 supports migration of the melanoma cells via vinculin down-regulation.

scientific article

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

scientific article published in December 2015

Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors

scientific article published on 06 June 2020

Cells and Viruses

scientific article published in 2013

Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock.

scientific article published on 6 May 2015

Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes

scientific article published on 19 October 2014

Expression of a constitutively active mutant of heat shock factor 1 under the control of testis-specific hst70 gene promoter in transgenic mice induces degeneration of seminiferous epithelium

scientific article published on 01 January 2003

Finding targets of transcriptional regulators--chromatin immunoprecipitation assay (ChIP)

scientific article published on January 1, 2011

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

scientific article published on 16 November 2021

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling

scientific article published on 24 May 2020

Heat shock transcription factor 1 down-regulates spermatocyte-specific 70 kDa heat shock protein expression prior to the induction of apoptosis in mouse testes.

scientific article published on April 2007

Identification of a new mouse sperm acrosome-associated protein

scientific article

Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

scientific article published on 08 July 2013

In vivo electroporation of the testis versus transgenic mice model in functional studies of spermatocyte-specific hst70 gene promoter: A comparative study

scientific article published on August 2003

Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism

scientific article published on 01 April 2007

Interplay between HSF1 and p53 signaling pathways in cancer initiation and progression: non-oncogene and oncogene addiction.

scientific article

Location of promoter elements necessary and sufficient to direct testis-specific expression of the Hst70/Hsp70.2 gene

scientific article published on May 2004

MAR/SAR elements flank the rat hst70 gene transcription unit.

scientific article published in January 2004

NF-κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins

scientific article

NGS Analysis of Liquid Biopsy (LB) and Formalin-Fixed Paraffin-Embedded (FFPE) Melanoma Samples Using Oncomine™ Pan-Cancer Cell-Free Assay

scientific article published on 16 July 2021

Overexpression of Heat Shock Transcription Factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel.

scientific article

PHLDA1 Does Not Contribute Directly to Heat Shock-Induced Apoptosis of Spermatocytes.

scientific article

Pleiotropic role of HSF1 in neoplastic transformation

scientific article

Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells.

scientific article

Pro-inflammatory cytokine and high doses of ionizing radiation have similar effects on the expression of NF-kappaB-dependent genes.

scientific article published on 21 February 2018

Promoter of the heat shock testis-specific Hsp70.2/Hst70 gene is active in nervous system during embryonic development of mice.

scientific article published on 18 October 2006

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

scientific article published on 30 April 2018

RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

article

SPEN protein expression and interactions with chromatin in mouse testicular cells

scientific article published on 07 June 2018

Structure of the 5' region of the Hst70 gene transcription unit: presence of an intron and multiple transcription initiation sites.

scientific article published in October 2001

The GC-box is critical for high level expression of the testis-specific Hsp70.2/Hst70 gene

scientific article published on 20 February 2007

The Role of Heat Shock Factors in Mammalian Spermatogenesis

scientific article

The activity of acid phosphatase and the level of storage proteins during the early stages of germination of Lupinus luteus L. and Lupinus angustifolius L. seeds

scientific article published in 2014

The expression pattern of the 70-kDa heat shock protein Hspa2 in mouse tissues.

scientific article

The expression patterns of heat shock genes and proteins and their role during vertebrate's development

scientific article published on 17 April 2011

The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism

scientific article published in September 2021

The role of NF-κB transcription factor in cellular response to ionizing radiation

scientific article published on 20 May 2019

[The heat shock response and HSP70 gene expression in male germ cells]

scientific article published on 01 January 2006

List of works by Wieslawa Widlak

17β-Estradiol Activates HSF1 via MAPK Signaling in ERα-Positive Breast Cancer Cells

A 252 bp upstream region of the rat spermatocyte-specific hst70 gene is sufficient to promote expression of the hst70-CAT hybrid gene in testis and brain of transgenic mice

Active heat shock transcription factor 1 supports migration of the melanoma cells via vinculin down-regulation.

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors

Cells and Viruses

Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock.

Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes

Expression of a constitutively active mutant of heat shock factor 1 under the control of testis-specific hst70 gene promoter in transgenic mice induces degeneration of seminiferous epithelium

Finding targets of transcriptional regulators--chromatin immunoprecipitation assay (ChIP)

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

Heat shock response regulates stimulus-specificity and sensitivity of the pro-inflammatory NF-κB signalling

Heat shock transcription factor 1 down-regulates spermatocyte-specific 70 kDa heat shock protein expression prior to the induction of apoptosis in mouse testes.

Identification of a new mouse sperm acrosome-associated protein

Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

In vivo electroporation of the testis versus transgenic mice model in functional studies of spermatocyte-specific hst70 gene promoter: A comparative study

Inducible 70 kDa heat shock protein does not protect spermatogenic cells from damage induced by cryptorchidism

Interplay between HSF1 and p53 signaling pathways in cancer initiation and progression: non-oncogene and oncogene addiction.

Location of promoter elements necessary and sufficient to direct testis-specific expression of the Hst70/Hsp70.2 gene

MAR/SAR elements flank the rat hst70 gene transcription unit.

NF-κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins

NGS Analysis of Liquid Biopsy (LB) and Formalin-Fixed Paraffin-Embedded (FFPE) Melanoma Samples Using Oncomine™ Pan-Cancer Cell-Free Assay

Overexpression of Heat Shock Transcription Factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel.

PHLDA1 Does Not Contribute Directly to Heat Shock-Induced Apoptosis of Spermatocytes.

Pleiotropic role of HSF1 in neoplastic transformation

Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells.

Pro-inflammatory cytokine and high doses of ionizing radiation have similar effects on the expression of NF-kappaB-dependent genes.

Promoter of the heat shock testis-specific Hsp70.2/Hst70 gene is active in nervous system during embryonic development of mice.

Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

SPEN protein expression and interactions with chromatin in mouse testicular cells

Structure of the 5' region of the Hst70 gene transcription unit: presence of an intron and multiple transcription initiation sites.

The GC-box is critical for high level expression of the testis-specific Hsp70.2/Hst70 gene

The Role of Heat Shock Factors in Mammalian Spermatogenesis

The activity of acid phosphatase and the level of storage proteins during the early stages of germination of Lupinus luteus L. and Lupinus angustifolius L. seeds

The expression pattern of the 70-kDa heat shock protein Hspa2 in mouse tissues.

The expression patterns of heat shock genes and proteins and their role during vertebrate's development

The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism

The role of NF-κB transcription factor in cellular response to ionizing radiation

[The heat shock response and HSP70 gene expression in male germ cells]