List of works - Stephen M Tompkins

A europium fluoroimmunoassay for measuring binding of antigen to class II MHC glycoproteins

scientific article published on 01 August 1993

A humanized anti-M2 scFv shows protective in vitro activity against influenza

scientific article published on 02 December 2008

Adenovirus 36, adiposity, and bone strength in late-adolescent females.

scientific article

Aerosol inoculation with a sub-lethal influenza virus leads to exacerbated morbidity and pulmonary disease pathogenesis.

scientific article

Aerosol vaccination induces robust protective immunity to homologous and heterologous influenza infection in mice.

scientific article

An array of possibilities for multiple sclerosis

scientific article published on 01 May 2002

Animal models for evaluation of influenza vaccines.

scientific article published on January 2009

Antiviral responses by Swine primary bronchoepithelial cells are limited compared to human bronchoepithelial cells following influenza virus infection.

scientific article

Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment.

scientific article

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity ⬇️

scientific article (publication date: 28 June 1991)

Characterizing Emerging Canine H3 Influenza Viruses

scientific article published on 14 April 2020

Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).

scientific article

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

scientific article

Death as a study endpoint: why use ferrets?

scientific article published on 01 August 2008

Domestic Cats Are Susceptible to Infection With Low Pathogenic Avian Influenza Viruses From Shorebirds ⬇️

scientific article published on June 25, 2012

Drug analog inhibition of indoleamine 2,3-dioxygenase (IDO) activity modifies pattern recognition receptor expression and proinflammatory cytokine responses early during influenza virus infection.

scientific article

Efficacy of a parainfluenza virus 5 (PIV5)-based H7N9 vaccine in mice and guinea pigs: antibody titer towards HA was not a good indicator for protection.

scientific article

Gene silencing in the therapy of influenza and other respiratory diseases: Targeting to RNase P by use of External Guide Sequences (EGS).

scientific article published on December 2007

Genetic control of immune responses to influenza A matrix 2 protein (M2)

article

Hydrophobic inactivation of influenza viruses confers preservation of viral structure with enhanced immunogenicity

scientific article published on 27 February 2008

Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs.

scientific article

Identification of altered MicroRNA expression in canine lymphoid cell lines and cases of B- and T-Cell lymphomas.

scientific article published on 24 August 2011

Identification of virulence determinants in influenza viruses ⬇️

scientific article

In ovo and in vitro susceptibility of American alligators (Alligator mississippiensis) to avian influenza virus infection.

scientific article

Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge

scientific article published on 04 April 2014

Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection

scientific article

Influenza Research & Development - GTCBio's Third Annual Conference (July 9-11 - Boston, Massachusetts, USA, 2014).

scientific article published in August 2014

Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection

scientific article published on 10 March 2015

Low pathogenic avian influenza isolates from wild birds replicate and transmit via contact in ferrets without prior adaptation

scientific article

Matrix Protein 2 Extracellular Domain-Specific Monoclonal Antibodies Are an Effective and Potentially Universal Treatment for Influenza A

scientific article published on 02 December 2020

Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1

scientific article published on March 2007

Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity.

scientific article

Moving Forward: Recent Developments for the Ferret Biomedical Research Model

scientific article published on 17 July 2018

Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets

scientific article published on 08 January 2014

Novel H7N9 influenza virus shows low infectious dose, high growth rate, and efficient contact transmission in the guinea pig model

scientific article

One-step assay for detecting influenza virus using dynamic light scattering and gold nanoparticles.

scientific article published on 13 June 2011

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

scientific article published on 27 July 2018

Passage of low-pathogenic avian influenza (LPAI) viruses mediates rapid genetic adaptation of a wild-bird isolate in poultry.

scientific article

Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells

scientific article

Potential directions for chicken immunology research.

scientific article published on 21 May 2013

Potential for Low-Pathogenic Avian H7 Influenza A Viruses To Replicate and Cause Disease in a Mammalian Model

scientific article

Protection against lethal influenza virus challenge by RNA interference in vivo.

scholarly article

Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice ⬇️

scientific article published on October 17, 2012

Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge

scientific article

Recombinant parainfluenza virus 5 expressing hemagglutinin of influenza A virus H5N1 protected mice against lethal highly pathogenic avian influenza virus H5N1 challenge.

scientific article published on 17 October 2012

Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replication.

scientific article published on 15 August 2012

SARS-CoV-2 spike protein binds heparan sulfate in a length- and sequence-dependent manner

scientific article published on 11 May 2020

Single-dose vaccination of a recombinant parainfluenza virus 5 expressing NP from H5N1 virus provides broad immunity against influenza A viruses ⬇️

scientific article published on March 20, 2013

Subsisting H1N1 influenza memory responses are insufficient to protect from pandemic H1N1 influenza challenge in C57BL/6 mice

scientific article

Swine Influenza Virus PA and Neuraminidase Gene Reassortment into Human H1N1 Influenza Virus Is Associated with an Altered Pathogenic Phenotype Linked to Increased MIP-2 Expression

scientific article

Theiler's virus-mediated autoimmunity: local presentation of CNS antigens and epitope spreading.

scientific article

Transporters Associated with Antigen Processing (TAP)-independent Presentation of Soluble Insulin to α/β T Cells by the Class Ib Gene Product, Qa-1b ⬇️

scientific article published on September 7, 1998

Vaccination with Recombinant Parainfluenza Virus 5 Expressing Neuraminidase Protects against Homologous and Heterologous Influenza Virus Challenge.

scientific article published on 20 September 2017

Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo.

scientific article

Virus-vectored influenza virus vaccines

scientific article

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning

scientific article published on 28 January 2013

List of works by Stephen M Tompkins

A europium fluoroimmunoassay for measuring binding of antigen to class II MHC glycoproteins

A humanized anti-M2 scFv shows protective in vitro activity against influenza

Adenovirus 36, adiposity, and bone strength in late-adolescent females.

Aerosol inoculation with a sub-lethal influenza virus leads to exacerbated morbidity and pulmonary disease pathogenesis.

Aerosol vaccination induces robust protective immunity to homologous and heterologous influenza infection in mice.

An array of possibilities for multiple sclerosis

Animal models for evaluation of influenza vaccines.

Antiviral responses by Swine primary bronchoepithelial cells are limited compared to human bronchoepithelial cells following influenza virus infection.

Bat cells from Pteropus alecto are susceptible to influenza A virus infection and reassortment.

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity ⬇️

Characterizing Emerging Canine H3 Influenza Viruses

Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

Death as a study endpoint: why use ferrets?

Domestic Cats Are Susceptible to Infection With Low Pathogenic Avian Influenza Viruses From Shorebirds ⬇️

Drug analog inhibition of indoleamine 2,3-dioxygenase (IDO) activity modifies pattern recognition receptor expression and proinflammatory cytokine responses early during influenza virus infection.

Efficacy of a parainfluenza virus 5 (PIV5)-based H7N9 vaccine in mice and guinea pigs: antibody titer towards HA was not a good indicator for protection.

Gene silencing in the therapy of influenza and other respiratory diseases: Targeting to RNase P by use of External Guide Sequences (EGS).

Genetic control of immune responses to influenza A matrix 2 protein (M2)

Hydrophobic inactivation of influenza viruses confers preservation of viral structure with enhanced immunogenicity

Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs.

Identification of altered MicroRNA expression in canine lymphoid cell lines and cases of B- and T-Cell lymphomas.

Identification of virulence determinants in influenza viruses ⬇️

In ovo and in vitro susceptibility of American alligators (Alligator mississippiensis) to avian influenza virus infection.

Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge

Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection

Influenza Research & Development - GTCBio's Third Annual Conference (July 9-11 - Boston, Massachusetts, USA, 2014).

Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection

Low pathogenic avian influenza isolates from wild birds replicate and transmit via contact in ferrets without prior adaptation

Matrix Protein 2 Extracellular Domain-Specific Monoclonal Antibodies Are an Effective and Potentially Universal Treatment for Influenza A

Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1

Memory T cells generated by prior exposure to influenza cross react with the novel H7N9 influenza virus and confer protective heterosubtypic immunity.

Moving Forward: Recent Developments for the Ferret Biomedical Research Model

Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets

Novel H7N9 influenza virus shows low infectious dose, high growth rate, and efficient contact transmission in the guinea pig model

One-step assay for detecting influenza virus using dynamic light scattering and gold nanoparticles.

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

Passage of low-pathogenic avian influenza (LPAI) viruses mediates rapid genetic adaptation of a wild-bird isolate in poultry.

Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells

Potential directions for chicken immunology research.

Potential for Low-Pathogenic Avian H7 Influenza A Viruses To Replicate and Cause Disease in a Mammalian Model

Protection against lethal influenza virus challenge by RNA interference in vivo.

Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice ⬇️

Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge

Recombinant parainfluenza virus 5 expressing hemagglutinin of influenza A virus H5N1 protected mice against lethal highly pathogenic avian influenza virus H5N1 challenge.

Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replication.

SARS-CoV-2 spike protein binds heparan sulfate in a length- and sequence-dependent manner

Single-dose vaccination of a recombinant parainfluenza virus 5 expressing NP from H5N1 virus provides broad immunity against influenza A viruses ⬇️

Subsisting H1N1 influenza memory responses are insufficient to protect from pandemic H1N1 influenza challenge in C57BL/6 mice

Swine Influenza Virus PA and Neuraminidase Gene Reassortment into Human H1N1 Influenza Virus Is Associated with an Altered Pathogenic Phenotype Linked to Increased MIP-2 Expression

Theiler's virus-mediated autoimmunity: local presentation of CNS antigens and epitope spreading.

Transporters Associated with Antigen Processing (TAP)-independent Presentation of Soluble Insulin to α/β T Cells by the Class Ib Gene Product, Qa-1b ⬇️

Vaccination with Recombinant Parainfluenza Virus 5 Expressing Neuraminidase Protects against Homologous and Heterologous Influenza Virus Challenge.

Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo.

Virus-vectored influenza virus vaccines

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning