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List of works by Randy R Brutkiewicz

A Thr/Ser dual residue motif in the cytoplasmic tail of human CD1d is important for the down-regulation of antigen presentation following a herpes simplex virus 1 infection.

scientific article published in October 2013

A VP22-Null HSV-1 Is Impaired in Inhibiting CD1d-Mediated Antigen Presentation.

scientific article published on 21 June 2016

A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus

scientific article published on 01 April 2007

Ability of sera from mice treated with Ge-132, an organic germanium compound, to inhibit experimental murine ascites tumours.

scientific article

Alterations in cellular metabolism modulate CD1d-mediated NKT-cell responses.

scientific article published on 12 June 2016

An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD

scientific article published on 20 February 2013

Anthrax lethal toxin impairs CD1d-mediated antigen presentation by targeting the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway.

scientific article

Apoptosis-induced inhibition of CD1d-mediated antigen presentation: different roles for caspases and signal transduction pathways.

scientific article

CD1 recognition by mouse NK1+ T lymphocytes

scientific journal article

CD1d expression on and regulation of murine hematopoietic stem and progenitor cells.

scientific article

CD1d ligands: the good, the bad, and the ugly

scientific article

CD1d-mediated antigen presentation to natural killer T (NKT) cells.

scientific article published on January 2003

CD1d1-dependent control of the magnitude of an acute antiviral immune response

scientific article published in March 2004

CD44 differentially activates mouse NK T cells and conventional T cells

scientific article published on 01 July 2006

Cell Signaling Pathways That Regulate Antigen Presentation

scientific article published on October 2016

Critical role of NKT cells in posttransplant alloantibody production.

scientific article

Defective presentation of the CD1d1-restricted natural Va14Ja18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency

scholarly article

Development of a quantitative cell-based intracellular ELISA for the screening of B cell hybridoma supernatants: a novel rapid assay to detect positive clones

scientific article published on 01 December 2004

Disruption of MHC class II-restricted antigen presentation by vaccinia virus.

scientific article published on November 2005

Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production

scientific article published on 20 March 2012

Forming a complex with MHC class I molecules interferes with mouse CD1d functional expression

scientific article

Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression.

scientific article published in October 2001

Human immunodeficiency virus gp120 downregulates CD1d cell surface expression.

scientific article published on 24 November 2004

Immune evasion of the CD1d/NKT cell axis

scholarly article by Randy R Brutkiewicz et al published June 2018 in Current Opinion in Immunology

Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex.

scientific article

Inhibition of CD1d-mediated antigen presentation by the transforming growth factor-β/Smad signalling pathway.

scientific article

Inhibition of CD1d1-mediated antigen presentation by the vaccinia virus B1R and H5R molecules.

scientific article published in October 2006

Inhibition of antitumor immunity by invariant natural killer T cells in a T-cell lymphoma model in vivo

scientific article published on June 2006

Inhibition of glycolipid shedding rescues recognition of a CD1+ T cell lymphoma by natural killer T (NKT) cells.

scientific article

JNK2 modulates the CD1d-dependent and -independent activation of iNKT cells

scientific article published on 03 December 2018

Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum

scientific article published in January 2002

Lipids-Я-Us: peroxisome generation of iNKT ligands

scientific article published on 18 April 2012

Multiple antigen-specific processing pathways for activating naive CD8+ T cells in vivo

scientific article published on 01 April 2001

Myeloid marker expression on antiviral CD8+ T cells following an acute virus infection.

scientific article published in October 2003

Natural killer T (NKT) cells and their role in antitumor immunity.

scientific article

Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.

scientific article

Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma.

scientific article published in January 2017

Protein kinase C delta is a critical regulator of CD1d-mediated antigen presentation.

scientific article published on September 2007

Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells.

scientific article

Reduction in CD1d expression on dendritic cells and macrophages by an acute virus infection.

scientific article published on 17 November 2004

Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2

scientific article published on 01 January 2006

Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.

scientific article

Research faculty development: an historical perspective and ideas for a successful future.

scientific article

Role for IL-4 nonproducing NKT cells in CC-chemokine ligand 2-induced Th2 cell generation

scientific article published on 07 November 2005

Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells.

scientific article published on November 2002

STAT3 promotes CD1d-mediated lipid antigen presentation by regulating a critical gene in glycosphingolipid biosynthesis.

scientific article published on 11 August 2015

STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis

scientific article published on 19 April 2011

Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus.

scientific article

Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation.

scientific article

TAP-independent, beta 2-microglobulin-dependent surface expression of functional mouse CD1.1.

scientific article

Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype.

scientific article published on 12 July 2010

The Toll-like receptor 9 signalling pathway regulates MR1-mediated bacterial antigen presentation in B cells.

scientific article published on 18 May 2017

The monoclonal antibody CZ-1 identifies a mouse CD45-associated epitope expressed on interleukin-2-responsive cells

scientific article published on 01 October 1993

Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma.

scientific article published on 16 April 2008

Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.

scientific article

Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II.

scientific article

Vesicular stomatitis virus matrix protein impairs CD1d-mediated antigen presentation through activation of the p38 MAPK pathway

scientific article published on 24 September 2008

Virus-encoded ectopic CD74 enhances poxvirus vaccine efficacy.

scientific article published on April 2014

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