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List of works by Loic Dupre

A biased competition theory of cytotoxic T lymphocyte interaction with tumor nodules

scientific article (publication date: 2015)

A proportion of patients with lymphoma may harbor mutations of the perforin gene.

scientific article

Actin cytoskeleton control of the comings and goings of T lymphocytes

scientific article published on 24 September 2013

An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse.

scientific article

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments

scientific article published on 19 September 2012

CIP4 controls CCL19-driven cell steering and chemotaxis in chronic lymphocytic leukemia.

scientific article published on 3 May 2013

Collective cell motility promotes chemotactic prowess and resistance to chemorepulsion

scientific article

Computational modelling of cell motility modes emerging from cell-matrix adhesion dynamics

scientific article published on 14 February 2022

CpG motifs induce Langerhans cell migration in vivo

scientific article published on 01 June 2000

Current understanding of the Wiskott-Aldrich syndrome and prospects for gene therapy.

scientific article

DC-SIGN-expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma.

scientific article

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

scientific article published on November 2006

EVER Proteins, Key Elements of the Natural Anti-Human Papillomavirus Barrier, Are Regulated upon T-Cell Activation ⬇️

scientific article published on June 28, 2012

Editorial: T-Cell Migration in Health and Disease.

scientific article published on 13 February 2017

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

scientific article published in March 2006

Features of the antibody response attributable to plasmid backbone adjuvanticity after DNA immunization.

scientific article

Granulysin- and granzyme-dependent elimination of myeloid cells by therapeutic ova-specific type 1 regulatory T cells

scientific article published on 01 March 2019

In vivo immunomodulation following intradermal injection with DNA encoding IL-18

scientific article published on 01 September 1999

Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing.

scientific article published on 27 May 2015

Inherited Perforin andFasMutations in a Patient with Autoimmune Lymphoproliferative Syndrome and Lymphoma

Interleukin-18 modulates immune responses induced by HIV-1 Nef DNA prime/protein boost vaccine

scientific article published on 01 August 2000

Intradermal immunization of rats with plasmid DNA encoding Schistosoma mansoni 28 kDa glutathione S-transferase

scientific article published on 01 November 1997

Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

scientific article

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

scientific article published on 19 October 2006

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott-Aldrich syndrome

scientific article published on 24 January 2022

Lymphoproliferative disease in patients with Wiskott-Aldrich syndrome: Analysis of the French Registry of Primary Immunodeficiencies

scientific article published on 20 February 2019

Mutations affecting the actin regulator WD repeat-containing protein 1 lead to aberrant lymphoid immunity

scientific article published on 08 May 2018

Myosin II governs collective cell migration behaviour downstream of guidance receptor signalling.

scientific article published on 31 March 2016

Plasticity of immunological synapses.

scientific article published on January 2010

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

scientific article published on 14 December 2017

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

scientific article

Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs.

scientific article

SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells.

scientific article

Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome

scientific article

Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes

scientific article

Surmounting the obstacles that impede effective CAR T cell trafficking to solid tumors

scientific article published on 03 July 2020

Switching between individual and collective motility in B lymphocytes is controlled by cell-matrix adhesion and inter-cellular interactions.

scientific article published on 11 April 2018

T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.

scientific article

T-cell defects in patients with germline mutations account for combined immunodeficiency

scientific article published on 25 September 2018

The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse.

scientific article published on 28 January 2018

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

scientific article

The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets.

scientific article published on 5 August 2010

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

scientific article published on 01 July 2020

The space and time frames of T cell activation at the immunological synapse ⬇️

scientific article published on October 14, 2010

WIP deficiency severely affects human lymphocyte architecture during migration and synapse assembly.

scientific article published on 13 September 2017

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

scientific article published in August 2002

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