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List of works by Elena Obrador

Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity.

scientific article published on 22 November 2004

Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma ⬇️

scientific article

Astrocytes protect neurons from Aβ1-42 peptide-induced neurotoxicity increasing TFAM and PGC-1 and decreasing PPAR-γ and SIRT-1.

scientific article published on January 2015

Bcl-2 and Mn-SOD antisense oligodeoxynucleotides and a glutamine-enriched diet facilitate elimination of highly resistant B16 melanoma cells by tumor necrosis factor-alpha and chemotherapy

scientific article published in November 2005

Bcl-2 and glutathione depletion sensitizes B16 melanoma to combination therapy and eliminates metastatic disease

scientific article published on 01 May 2007

Blood glutathione as an index of radiation-induced oxidative stress in mice and humans

scientific article published on 01 January 1997

Changes in glutathione status and the antioxidant system in blood and in cancer cells associate with tumour growth in vivo

scientific article published on 01 February 1999

Down-regulation of glutathione and Bcl-2 synthesis in mouse B16 melanoma cells avoids their survival during interaction with the vascular endothelium.

scientific article published on 24 July 2003

Effects of Ranolazine on Astrocytes and Neurons in Primary Culture

scientific article

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

scientific article published on 22 January 2019

Elimination of Ehrlich tumours by ATP-induced growth inhibition, glutathione depletion and X-rays

scientific article published on 01 January 1995

Glucocorticoid receptor knockdown decreases the antioxidant protection of B16 melanoma cells: an endocrine system-related mechanism that compromises metastatic cell resistance to vascular endothelium-induced tumor cytotoxicity

scientific article

Glutamine potentiates TNF-alpha-induced tumor cytotoxicity

scientific article published in September 2001

Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1

scientific article

Glutathione and the rate of cellular proliferation determine tumour cell sensitivity to tumour necrosis factor in vivo

scientific article published on July 1997

Glutathione in cancer biology and therapy

scientific article

Glutathione in metastases: From mechanisms to clinical applications

scientific article

Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature.

scientific article

Growth-associated changes in glutathione content correlate with liver metastatic activity of B16 melanoma cells

scientific article published on 01 January 1999

Inhibition of cancer growth and selective glutathione depletion in Ehrlich tumour cells in vivo by extracellular ATP.

scientific article published on February 1994

Inhibition of cancer growth by resveratrol is related to its low bioavailability

scientific article

Intertissue flow of glutathione (GSH) as a tumor growth-promoting mechanism: interleukin 6 induces GSH release from hepatocytes in metastatic B16 melanoma-bearing mice

scientific article

Mitochondrial glutathione depletion by glutamine in growing tumor cells

scientific article published on 01 November 2000

Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanism.

scientific article

Neuronal Effects of Sugammadex in combination with Rocuronium or Vecuronium.

scientific article published on 23 February 2017

Nitric oxide mediates natural polyphenol-induced Bcl-2 down-regulation and activation of cell death in metastatic B16 melanoma.

scientific article published on 29 November 2006

Oxidative Stress and Antioxidants in the Pathophysiology of Malignant Melanoma

scientific article published on 01 April 2019

Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy

scientific article published on 27 June 2017

Possible mechanisms for tumour cell sensitivity to TNF-alpha and potential therapeutic applications

scientific article

Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism

scientific article published on 09 December 2015

Radioprotection and Radiomitigation: From the Bench to Clinical Practice

scientific article published on 30 October 2020

Regulation of tumour cell sensitivity to TNF-induced oxidative stress and cytotoxicity: role of glutathione

scientific article published in January 1998

Stress hormones promote growth of B16-F10 melanoma metastases: an interleukin 6- and glutathione-dependent mechanism.

scientific article published on 22 March 2013

Sugammadex, a neuromuscular blockade reversal agent, causes neuronal apoptosis in primary cultures.

scientific article published on 03 August 2013

Tumor cytotoxicity by endothelial cells. Impairment of the mitochondrial system for glutathione uptake in mouse B16 melanoma cells that survive after in vitro interaction with the hepatic sinusoidal endothelium.

scientific article

Tumoricidal activity of endothelial cells. Inhibition of endothelial nitric oxide production abrogates tumor cytotoxicity induced by hepatic sinusoidal endothelium in response to B16 melanoma adhesion in vitro

scientific article published on 19 April 2001

Tumoricidal activity of endothelium-derived NO and the survival of metastatic cells with high GSH and Bcl-2 levels

scientific article published on 23 April 2008

WIN 55,212-2, agonist of cannabinoid receptors, prevents amyloid β1-42 effects on astrocytes in primary culture.

scientific article published on 13 April 2015

gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver

scientific article

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