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List of works by David Smith

A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence

scientific article

A novel Lawsonia intracellularis autotransporter protein is a prominent antigen.

scientific article

A population genomics approach to exploiting the accessory 'resistome' of Escherichia coli

scientific article published on 06 April 2017

Adherence and pathogenesis of pasteurella multocida--a sticky problem

scientific article published on 01 May 2000

Adherence of Ureaplasma urealyticum to human epithelial cells.

scientific article published on October 1994

An investigation of the expression and adhesin function of H7 flagella in the interaction of Escherichia coli O157 : H7 with bovine intestinal epithelium.

scientific article published on 30 October 2008

Analysis of Campylobacter jejuni infection in the gnotobiotic piglet and genome-wide identification of bacterial factors required for infection.

scientific article

Analysis of the expression, regulation and export of NleA-E in Escherichia coli O157 : H7.

scientific article published in May 2007

Author Correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

scientific article published in Nature Communications

Campylobacter jejuni 81-176 forms distinct microcolonies on in vitro-infected human small intestinal tissue prior to biofilm formation

scientific article published on 08 July 2010

Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells

scientific article

Changes in anti-endotoxin-IgG antibody and endotoxaemia in three cases of gram-negative septic shock

scientific article published on 01 October 1989

Changes in sensitivity patterns to selected antibiotics in Clostridium difficile in geriatric in-patients over an 18-month period.

scientific article published in March 2003

Characterisation of proteins extracted from the surface of Salmonella Typhimurium grown under SPI-2-inducing conditions by LC-ESI/MS/MS sequencing.

scientific article published on 3 January 2011

Characterization of cell envelope proteins of Staphylococcus epidermidis cultured in human peritoneal dialysate.

scientific article published on February 1991

Characterization of the in vitro core surface proteome of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia

scientific article

Cloning, expression, and characterization of fimbrial operon F9 from enterohemorrhagic Escherichia coli O157:H7.

scientific article published in April 2006

Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7.

scientific article published in October 2004

Complete genome sequence of Corynebacterium pseudotuberculosis strain 1/06-A, isolated from a horse in North America.

scientific article

Complete genome sequences of Corynebacterium pseudotuberculosis strains 3/99-5 and 42/02-A, isolated from sheep in Scotland and Australia, respectively.

scientific article

Differences in levels of secreted locus of enterocyte effacement proteins between human disease-associated and bovine Escherichia coli O157

scientific article published on April 2005

Differential endometrial cell sensitivity to a cholesterol-dependent cytolysin links Trueperella pyogenes to uterine disease in cattle.

scientific article published on 13 March 2014

Draft Genome Sequence of Escherichia coli MS499, Isolated from the Infected Uterus of a Postpartum Cow with Metritis.

scientific article

Draft Genome Sequence of Isolate Staphylococcus aureus LHSKBClinical, Isolated from an Infected Hip

scientific article published on 30 April 2015

Draft Genome Sequence of Trueperella pyogenes, Isolated from the Infected Uterus of a Postpartum Cow with Metritis

scientific article published on 24 April 2014

Draft Genome Sequences of Enterohemorrhagic Escherichia coli Encoding Extended-Spectrum Beta-Lactamases.

scientific article

Effects of carbon dioxide and sub-lethal levels of antibiotics on adherence of coagulase-negative staphylococci to polystyrene and silicone rubber

scientific article published on 01 May 1991

Effects of sub-MIC concentrations of antibiotics on growth of and toxin production by Clostridium difficile

scientific article published on December 1, 2003

Escherichia coli O157 : H7 forms attaching and effacing lesions at the terminal rectum of cattle and colonization requires the LEE4 operon.

scientific article

Escherichia coli O157:H7 colonization in cattle following systemic and mucosal immunization with purified H7 flagellin.

scientific article published on 24 March 2008

EspP, a Type V-secreted serine protease of enterohaemorrhagic Escherichia coli O157:H7, influences intestinal colonization of calves and adherence to bovine primary intestinal epithelial cells.

scientific article published on 20 April 2007

Evidence of land-sea transfer of the zoonotic pathogen Campylobacter to a wildlife marine sentinel species.

scientific article published on 31 December 2014

Expression by Lawsonia intracellularis of type III secretion system components during infection.

scientific article published on 21 June 2009

Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle

scientific article published on 25 June 2012

Functional analysis of bovine TLR5 and association with IgA responses of cattle following systemic immunisation with H7 flagella.

scientific article published on 19 February 2015

Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin.

scientific article published on 30 December 2013

Gamma interferon influences intestinal epithelial hyperplasia caused by Lawsonia intracellularis infection in mice

scientific article published on December 2000

Genetic variability of Chlamydophila abortus strains assessed by PCR-RFLP analysis of polymorphic membrane protein-encoding genes.

scientific article published on 10 March 2011

Genome Sequence of Lawsonia intracellularis Strain N343, Isolated from a Sow with Hemorrhagic Proliferative Enteropathy

scientific article

Genome-wide fitness analyses of the foodborne pathogen Campylobacter jejuni in in vitro and in vivo models

scientific article published on 28 April 2017

Genomic characterisation of an endometrial pathogenic Escherichia coli strain reveals the acquisition of genetic elements associated with extra-intestinal pathogenicity.

scientific article

Genomic content typifying a prevalent clade of bovine mastitis-associated Escherichia coli.

scientific article

Heterogeneous Surface Expression of EspA Translocon Filaments by Escherichia coli O157:H7 Is Controlled at the Posttranscriptional Level

scientific article published on October 1, 2003

Host species adaptation of TLR5 signalling and flagellin recognition.

scientific article published on 15 December 2017

Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

scientific article published in Nature Communications

Host-response patterns of intramammary infections in dairy cows.

scientific article published on 10 September 2011

Hydrolysis of urea by Ureaplasma urealyticum generates a transmembrane potential with resultant ATP synthesis.

scientific article

Identification of equine proliferative enteropathy

scientific article published on 01 November 1998

Immunization of cattle with a combination of purified intimin-531, EspA and Tir significantly reduces shedding of Escherichia coli O157:H7 following oral challenge

scientific article published on 10 November 2009

Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection.

scientific article published on 28 May 2018

Immunopathogenesis of experimentally induced proliferative enteropathy in pigs

scientific article published on 01 July 2003

In vitro antagonistic activities of Lactobacillus spp. against Brachyspira hyodysenteriae and Brachyspira pilosicoli

scientific article published on 20 March 2009

Infection of cultured rat enterocytes by Ileal symbiont intracellularis depends on host cell function and actin polymerisation

scientific article published on 01 August 1995

Influence of carbon dioxide on growth and antibiotic susceptibility of coagulase-negative staphylococci cultured in human peritoneal dialysate.

scientific article published on October 1990

Lipopolysaccharide core type diversity in the Escherichia coli species in association with phylogeny, virulence gene repertoire and distribution of type VI secretion systems

scientific article published in 2021

Local immunization impacts the response of dairy cows to Escherichia coli mastitis.

scientific article

MALDIrppa: quality control and robust analysis for mass spectrometry data

scientific article

Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis

scientific article

Microbial biofilms: does breaking the microbes' community spirit hold the key to beating persistent mastitis?

scientific article published on 01 May 2006

Novel Single Nucleotide Polymorphism-Based Assay for Genotyping Mycobacterium avium subsp. paratuberculosis

scientific article published on 16 December 2015

Optimizing the Protection of Cattle against Escherichia coli O157:H7 Colonization through Immunization with Different Combinations of H7 Flagellin, Tir, Intimin-531 or EspA

scientific article

Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning.

scientific article published in March 2009

Peripheral blood leukocytes of cows with subclinical endometritis show an altered cellular composition and gene expression.

scientific article published on 28 January 2014

Phenotypic and functional characterisation of follicle-associated epithelium of rectal lymphoid tissue.

scientific article published on 17 June 2005

Phenotypic and functional heterogeneity of bovine blood monocytes

scientific article

Phosphorylation of the epidermal growth factor receptor (EGFR) is essential for interleukin-8 release from intestinal epithelial cells in response to challenge with Escherichia coli O157 : H7 flagellin.

scientific article

Phylogenomic exploration of the relationships between strains of Mycobacterium avium subspecies paratuberculosis

scientific article published on 26 January 2016

Postgenomics Characterization of an Essential Genetic Determinant of Mammary Pathogenic Escherichia coli.

scientific article published on 3 April 2018

Proteomic analysis of Lawsonia intracellularis reveals expression of outer membrane proteins during infection.

scientific article published on 8 November 2014

Proteomic and genomic analysis reveals novel Campylobacter jejuni outer membrane proteins and potential heterogeneity

scientific article published on 26 June 2014

Rapid and robust analytical protocol for E. coli STEC bacteria subspecies differentiation using whole cell MALDI mass spectrometry.

scientific article published on 20 February 2018

Rectal carriage of enterohemorrhagic Escherichia coli O157 in slaughtered cattle.

scientific article

Risk factors associated with Lawsonia intracellularis in English pig farms.

scientific article published on 14 May 2013

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain.

scientific article published on 20 April 2007

Simple methods for measurement of bovine mucosal antibody responses in vivo

scientific article published on 03 May 2007

Staphylococcus aureus Phenol-Soluble Modulins Impair Interleukin Expression in Bovine Mammary Epithelial Cells.

scientific article published on 21 March 2016

Superoxide dismutase SodB is a protective antigen against Campylobacter jejuni colonisation in chickens

scientific article

Targeted allele replacement mutagenesis of Corynebacterium pseudotuberculosis.

scientific article published on 18 March 2011

The bile salt sodium taurocholate induces Campylobacter jejuni outer membrane vesicle production and increases OMV-associated proteolytic activity

scientific article published on 4 December 2017

The host metabolite D-serine contributes to bacterial niche specificity through gene selection

scientific article published on 17 March 2015

The host metabolite D-serine contributes to bacterial niche specificity through gene selection.

scientific article

Ultra-fast tandem mass spectrometry scanning combined with monolithic column liquid chromatography increases throughput in proteomic analysis.

scientific article

Unexpected differential metabolic responses of Campylobacter jejuni to the abundant presence of glutamate and fucose

article

Urea-hydrolysis-dependent citrulline synthesis by Ureaplasma urealyticum

scientific article published on 01 November 1992

Use of metronidazole in equine acute idiopathic toxaemic colitis.

scientific article published in June 1998

Variation in the expression of cell envelope proteins of coagulase-negative staphylococci cultured under iron-restricted conditions in human peritoneal dialysate

scientific article published on 01 November 1991

Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity.

scientific article

Verotoxin-2 activates mitogen-activated protein kinases in bovine adherent peripheral blood mononuclear cells.

scientific article published on 19 October 2011