List of works - Colin T Shearn

4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.

scientific article

Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury

scientific article

Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro

scientific article published on 3 July 2008

Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics

scientific article

Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney

scientific article published on 6 July 2015

Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice

scientific article published on 27 November 2015

Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice.

scientific article

Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis

scientific article published on March 2013

Knockout of the Gsta4 Gene in Male Mice Leads to an Altered Pattern of Hepatic Protein Carbonylation and Enhanced Inflammation Following Chronic Consumption of an Ethanol Diet

scientific article published on 30 May 2018

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

scientific article

Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease

scientific article

Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function.

scientific article

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Inhibition by 4-Hydroxynonenal Leads to Increased Akt Activation in Hepatocytes ⬇️

scientific article published on March 17, 2011

Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion

scientific article

Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism

scientific article published on 31 January 2019

Role of Nutrition in Alcoholic Liver Disease: Summary of the Symposium at the ESBRA 2017 Congress.

scientific article

Susceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver.

scientific article published on 28 January 2013

List of works by Colin T Shearn

4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.

Aberrant post-translational protein modifications in the pathogenesis of alcohol-induced liver injury

Carbonyl reductase inactivation may contribute to mouse lung tumor promotion by electrophilic metabolites of butylated hydroxytoluene: protein alkylation in vivo and in vitro

Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics

Chronic ethanol consumption induces mitochondrial protein acetylation and oxidative stress in the kidney

Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice

Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice.

Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis

Knockout of the Gsta4 Gene in Male Mice Leads to an Altered Pattern of Hepatic Protein Carbonylation and Enhanced Inflammation Following Chronic Consumption of an Ethanol Diet

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage

Oxidative Stress and the ER Stress Response in a Murine Model for Early-Stage Alcoholic Liver Disease

Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function.

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Inhibition by 4-Hydroxynonenal Leads to Increased Akt Activation in Hepatocytes ⬇️

Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion

Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism

Role of Nutrition in Alcoholic Liver Disease: Summary of the Symposium at the ESBRA 2017 Congress.

Susceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver.