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List of works by Christine E Brown

A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling

scientific article (publication date: 2014)

A quantitative high-throughput chemotaxis assay using bioluminescent reporter cells.

scientific article published in July 2005

Acute myeloid leukemia therapeutics: CARs in the driver's seat.

scientific article

Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma.

scientific article

CAR T cells for brain tumors: Lessons learned and road ahead

scientific article published on 01 July 2019

CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells.

scientific article published on 2 April 2015

CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

scientific article published on 16 December 2020

Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant ⬇️

scientific article published on September 1, 1998

Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications

scientific article published on 22 December 2017

Chimeric antigen receptor T-cell therapy for glioblastoma

scientific article

Chimeric antigen receptor signaling: Functional consequences and design implications

scientific article published on 20 May 2020

Chimeric antigen receptors with mutated IgG4 Fc spacer avoid fc receptor binding and improve T cell persistence and antitumor efficacy

scientific article

Chimeric γc cytokine receptors confer cytokine independent engraftment of human T lymphocytes.

scientific article

Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

scientific article published on 01 March 2020

Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer.

scientific article published on 16 October 2017

Contact and encirclement of glioma cells in vitro is an intrinsic behavior of a clonal human neural stem cell line

scientific article

Conversion of a tumor-binding peptide identified by phage display to a functional chimeric T cell antigen receptor.

scientific article

Cytokine induction of VCAM-1 but not IL13Rα2 on glioma cells: a tale of two antibodies

scientific article

Cytotoxic T lymphocyte trafficking and survival in an augmented fibrin matrix carrier

scientific article

Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes.

scientific article published on February 2014

Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy

scientific article published on 26 January 2022

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.

scientific article published on 3 February 2016

Efficient selection of genetically modified human T cells using methotrexate-resistant human dihydrofolate reductase.

scientific article

Engineering human T cells for resistance to methotrexate and mycophenolate mofetil as an in vivo cell selection strategy

scientific article (publication date: 2013)

Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells.

scientific article

Glioma IL13Rα2 is associated with mesenchymal signature gene expression and poor patient prognosis

scientific article

IFNγ Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity

scientific article published on 09 April 2021

Induction of anti-glioma natural killer cell response following multiple low-dose intracerebral CpG therapy

scientific article

L1 Cell Adhesion Molecule-Specific Chimeric Antigen Receptor-Redirected Human T Cells Exhibit Specific and Efficient Antitumor Activity against Human Ovarian Cancer in Mice

scientific article published on 13 January 2016

Lenalidomide Enhances the Function of CS1 Chimeric Antigen Receptor-Redirected T Cells Against Multiple Myeloma.

scientific article

Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use.

scientific article published on 06 September 2013

Medulloblastomas expressing IL13Ralpha2 are targets for IL13-zetakine+ cytolytic T cells.

scientific article

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.

scientific article published on 28 October 2013

Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma.

scientific article published on 5 October 2017

PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae

scientific article

PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89Zr-Oxine

scientific article published on 04 May 2018

Phase 1 studies of central memory-derived CD19 CAR T-cell therapy following autologous HSCT in patients with B-cell NHL.

scientific article published on 26 April 2016

Phenotypic and Functional Attributes of Lentivirus-modified CD19-specific Human CD8+ Central Memory T Cells Manufactured at Clinical Scale ⬇️

scientific article published on November 1, 2012

Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation.

scientific article

Recognition and killing of brain tumor stem-like initiating cells by CD8+ cytolytic T cells.

scientific article published on 10 November 2009

Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain.

scientific article published on 23 October 2017

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

scientific article

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma.

scientific article published on January 2017

Significance of interleukin-13 receptor alpha 2-targeted glioblastoma therapy.

scientific article published on 10 April 2014

Smart CARs engineered for cancer immunotherapy

scientific article

Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3

scientific article

Stem-like Tumor-Initiating Cells Isolated from IL13Rα2 Expressing Gliomas Are Targeted and Killed by IL13-Zetakine–Redirected T Cells ⬇️

scientific article published on March 8, 2012

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia.

scientific article published on 12 September 2013

TLR9 is critical for glioma stem cell maintenance and targeting

scientific article

Targeting Alpha-Fetoprotein (AFP)-MHC Complex with CAR T-Cell Therapy for Liver Cancer.

scientific article

The cerebroventricular environment modifies CAR T cells for potent activity against both central nervous system and systemic lymphoma

scientific article published on 22 October 2020

Transcription activator interactions with multiple SWI/SNF subunits.

scientific article

Tumor PD-L1 co-stimulates primary human CD8(+) cytotoxic T cells modified to express a PD1:CD28 chimeric receptor.

scientific article

Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells.

scientific article published on September 2007

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