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List of works by Ilda D'Annessa

A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction.

scientific article published on 19 December 2012

A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.

scientific article published on 4 September 2008

Binding of an Indenoisoquinoline to the topoisomerase-DNA complex induces reduction of linker mobility and strengthening of protein-DNA interaction

scientific article

Development of derivatives of 3, 3'-diindolylmethane as potent Leishmania donovani bi-subunit topoisomerase IB poisons

scientific article

Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I.

scientific article published on 15 January 2010

Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

scientific article published on 18 September 2009

Interaction between natural compounds and human topoisomerase I.

scientific article

Mapping multiple potential ATP binding sites on the matrix side of the bovine ADP/ATP carrier by the combined use of MD simulation and docking

scientific article published on 12 October 2011

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

scientific article

Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum

scientific article

Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex

scientific article

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