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List of works by Takumi Ito

A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase

scientific article

ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells

scientific article published on 21 September 2020

Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs.

scientific article

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

scientific article

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

scientific article published on 7 November 2012

Deciphering the mystery of thalidomide teratogenicity.

scientific article published on March 2012

Discovery of the target for immunomodulatory drugs (IMiDs).

scientific article published on May 2016

GABP, HCF-1 and YY1 are involved in Rb gene expression during myogenesis

scientific article published on 01 July 2005

Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide

scientific article published on 04 March 2020

High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads.

scientific article

Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol A

scientific article

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

scientific article

Myeloid disease: Another action of a thalidomide derivative.

scientific article

PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates

scientific article published on 11 November 2021

Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

scientific article

Teratogenic effects of thalidomide: molecular mechanisms ⬇️

scientific article published on January 5, 2011

Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound

scientific article published on 21 December 2011

Vesnarinone Suppresses TNFα mRNA Expression by Inhibiting Valosin-Containing Protein ⬇️

scientific article published on February 7, 2013

mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain.

scientific article published on 15 January 2011

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