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List of works by Leyre Mestre

2-AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs.

scientific article published on 27 February 2018

2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination.

scientific article

A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis

scientific article published on 07 April 2020

A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.

scientific article

A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules.

scientific article

An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

scientific article published on 6 October 2009

Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB.

scientific article

Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2).

scientific article published in February 2008

Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system

scientific article

CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation.

scientific article published on 31 May 2012

Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress

scientific article published on 28 June 2012

Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors.

scientific article published on 11 July 2013

Cannabinoid system and neuroinflammation: implications for multiple sclerosis.

scientific article published on 05 December 2007

Chemical probes for the recognition of cannabinoid receptors in native systems

scientific article

Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

scientific article published in November 2005

Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation

scientific article published on 16 January 2007

Gut dysbiosis and neuroimmune responses to brain infection with Theiler's murine encephalomyelitis virus.

scientific article published on 14 March 2017

Gut microbiota, cannabinoid system and neuroimmune interactions: New perspectives in multiple sclerosis

scientific article published on 30 August 2018

Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

scientific article published in March 2018

Identification of receptors and enzymes for endocannabinoids in NSC-34 cells: Relevance for in vitro studies with cannabinoids in motor neuron diseases ⬇️

scientific article published on December 22, 2011

Microglia activation states and cannabinoid system: Therapeutic implications.

scientific article published on 29 June 2016

Mobilization of progenitors in the subventricular zone to undergo oligodendrogenesis in the Theiler's virus model of multiple sclerosis: implications for remyelination at lesions sites

scientific article published on 19 October 2013

PDE7 inhibitor TC3.6 ameliorates symptomatology in a model of primary progressive multiple sclerosis

scientific article

Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis.

scientific article

Regulatory lymphocytes are key factors in MHC-independent resistance to EAE

scientific article

Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide

scientific article

The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells.

scientific article published on 16 February 2011

The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis.

scientific article published on January 2009

Therapeutic potential of CB2 targeting in multiple sclerosis

scientific article published on 01 February 2008

Viral models of multiple sclerosis: neurodegeneration and demyelination in mice infected with Theiler's virus.

scientific article

[Cannabinoid system and neuroinflammation:therapeutic perspectives in multiple sclerosis]

scientific article published on 01 November 2006

[Guidelines on the appropriate use of animal models for developing therapies in multiple sclerosis]

scientific article published on 01 January 2012

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