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List of works by Guillaume Robert

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus ⬇️

scientific article published on July 7, 2011

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

scientific article published on 24 July 2014

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

scientific article published on 23 December 2017

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

scientific article

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

scientific article published on December 1, 2012

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

scientific article

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

scientific article

Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?

scientific article published on 01 March 2019

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

scientific article published on 15 July 2011

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

scientific article published on 25 July 2016

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

scientific article published on 27 April 2017

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

scientific article published on 17 December 2018

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

scientific article published on 24 March 2016

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness

scientific article

FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.

scientific article

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

scientific article

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

scientific article published on 10 January 2018

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

scientific article

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

scientific article published on 30 September 2018

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies

scientific article published on 17 January 2017

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

scientific article published on 03 January 2019

Limbic versus cognitive target for deep brain stimulation in treatment-resistant depression: accumbens more promising than caudate.

scientific article published on 20 May 2014

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation.

scientific article published on 8 January 2013

Mechanism of action of the multikinase inhibitor Foretinib.

scientific article published in December 2011

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

scientific article published on November 1, 2011

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

scientific article

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

scientific article published on 3 May 2011

Modular synthesis of new C-aryl-nucleosides and their anti-CML activity

scientific article published on 24 March 2018

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

scientific article published on 23 November 2010

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

scientific article

Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

scientific article published on 26 January 2010

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

scientific article published on August 2006

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

scientific article published on December 2012

Sirtuin 7: a new marker of aggressiveness in prostate cancer

scientific article

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

scientific article published on 17 March 2009

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.

scientific article

Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides

scientific article

Targeting autophagy to fight hematopoietic malignancies.

scientific article published on 15 September 2010

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

scientific article

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

scientific article

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

scientific article published on May 4, 2012

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

scientific article published on 2 February 2018

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

scientific article

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

scientific article

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

scientific article published on 07 September 2006

Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.

scientific article published on 25 April 2012

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

scientific article published on 01 March 2017

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