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List of works by Christophe Cullin

A novel in vitro filter trap assay identifies tannic acid as an amyloid aggregation inducer for HET-s

scientific article published on 18 April 2006

A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

scientific article (publication date: 11 July 1993)

A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway

scientific article

A tensegrity driven DNA nanopore

scientific article published on 5 July 2017

A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity.

scientific article published on 10 August 2012

Assessment of human Nter and Cter BRCA1 mutations using growth and localization assays in yeast.

scientific article

Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain.

scientific article published on May 1994

Comparative studies of nontoxic and toxic amyloids interacting with membrane models at the air-water interface

scientific article published on 15 March 2011

Differential resistance to proteinase K digestion of the yeast prion-like (Ure2p) protein synthesized in vitro in wheat germ extract and rabbit reticulocyte lysate cell-free translation systems

scientific article published on 01 September 1997

ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency

scientific article

Extracts from two ubiquitous Mediterranean plants ameliorate cellular and animal models of neurodegenerative proteinopathies.

scientific article published on 2 December 2016

High speed atomic force microscopy to investigate the interactions between toxic Aβ1-42 peptides and model membranes in real time: impact of the membrane composition

scientific article published on 01 April 2019

In vivo and in vitro analyses of toxic mutants of HET-s: FTIR antiparallel signature correlates with amyloid toxicity.

scientific article published on 18 July 2011

Interaction of Aβ(1-42) amyloids with lipids promotes "off-pathway" oligomerization and membrane damage.

scientific article published on 26 February 2015

Interaction of Aβ1-42 peptide or their variant with model membrane of different composition probed by infrared nanospectroscopy.

scientific article published on 2 January 2018

Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells.

scientific article

Isolation of drugs active against mammalian prions using a yeast-based screening assay

scientific article published on 10 August 2003

Membrane domain modulation of Aβ1-42 oligomer interactions with supported lipid bilayers: an atomic force microscopy investigation

scientific article published on 28 October 2019

Nitrogen catabolic repression controls the release of volatile thiols by Saccharomyces cerevisiae during wine fermentation.

scientific article published on 7 May 2008

Ploidy controls [URE3] prion propagation in yeast

scientific article

Recombinant yeast in drug metabolism.

scientific article published on October 1993

Rubber elongation factor (REF), a major allergen component in Hevea brasiliensis latex has amyloid properties

scientific article

Structural characterization of Saccharomyces cerevisiae prion-like protein Ure2

scientific article published on 01 May 1999

Synthesis of functional mouse cytochromes P-450 P1 and chimeric P-450 P3-1 in the yeast Saccharomyces cerevisiae.

scientific article

Synthetic toxic Aβ1-42 oligomers can assemble in different morphologies.

scientific article published on 3 March 2017

The [URE3] phenotype: evidence for a soluble prion in yeast

scientific article published on December 19, 2001

The cellular concentration of the yeast Ure2p prion protein affects its propagation as a prion

scientific article published on 18 February 2009

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition

scientific article

The mechanisms of [URE3] prion elimination demonstrate that large aggregates of Ure2p are dead-end products.

scientific article published on October 2003

The toxicity of an "artificial" amyloid is related to how it interacts with membranes.

scientific article published on 23 October 2010

Tip-Enhanced Raman Spectroscopy to Distinguish Toxic Oligomers from Aβ1-42 Fibrils at the Nanometer Scale

scientific article published on 10 January 2017

Two distinct sequences control the targeting and anchoring of the mouse P450 1A1 into the yeast endoplasmic reticulum membrane

scientific article published on May 15, 1992

What does make an amyloid toxic: morphology, structure or interaction with membrane?

scientific article published on 20 July 2012

Yeast as a Model for Alzheimer's Disease: Latest Studies and Advanced Strategies.

scientific article published on January 2016

[Alpha-1 antitrypsin deficiency: A model of alteration of protein homeostasis or proteostasis]

scientific article published on 19 September 2015