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List of works by Alain Bousquet-Mélou

A nonlabeled method to evaluate cortisol production rate by modeling plasma CBG-free cortisol disposition.

scientific article

A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle.

scientific article published in July 2003

A pressurized liquid extraction approach followed by standard addition method and UPLC-MS/MS for a fast multiclass determination of antibiotics in a complex matrix

scientific article published on 07 August 2018

Allometric scaling for predicting human clearance of bisphenol A.

scientific article published on 7 March 2015

Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test

scientific article published on 01 November 2011

Author's Reply to Trechot: "Comment on Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?"

scientific article published on 01 July 2019

Authors' Reply to Castello-Bridoux et al.: "Comment on Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?"

scientific article published on 01 July 2019

Authors' Reply to Coste et al.: "Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?"

scientific article published on 01 July 2019

Authors' Reply to Krebs-Brown et al. Comment on: "Why Were More Than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One?"

scientific article published on 01 February 2020

Authors' Reply to Lechat et al.: "Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?"

scientific article published on 01 October 2019

Authors' Reply to Nicolas: "Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?"

scientific article published on 01 July 2019

Authors' Reply to Nicolas: "Why Were More than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One?"

scientific article published on 01 February 2020

Authors' Reply to Yu et al.: "Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients?"

scientific article published on 01 February 2020

Bacterial Species-Specific Activity of a Fluoroquinolone against Two Closely Related Pasteurellaceae with Similar MICs: Differential In Vitro Inoculum Effects and In Vivo Efficacies

scientific article published on 27 October 2015

Beta-3 adrenoceptor-mediated increase in cutaneous blood flow in the dog

scientific article published on 01 March 1994

Bioavailability and its assessment.

scientific article

Bisphenol A glucuronide deconjugation is a determining factor of fetal exposure to bisphenol A.

scientific article published on 24 October 2015

Capacity limits of asialoglycoprotein receptor-mediated liver targeting

scientific article published on 6 September 2017

Comment on "In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes".

scientific article published in December 2015

Comparison of hydroalcoholic rubbing and conventional chlorhexidine scrubbing for aseptic skin preparation in dogs

scientific article published on 29 April 2019

Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus

scientific article published in PLoS ONE

Comparison of the In vitro Activity of Five Antimicrobial Drugs against Staphylococcus pseudintermedius and Staphylococcus aureus Biofilms.

scientific article published on 2 August 2016

Comparison of the reduction in the antibacterial potency of a fluoroquinolone conferred by a single mutation in the quinolone resistance-determining region or by the inoculum size effect

scientific article published on 23 August 2014

Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans

scientific article published on 01 March 1995

Desensitization of beta-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase

scientific article published on 01 April 1995

Differential Activity of the Combination of Vancomycin and Amikacin on Planktonic vs. Biofilm-Growing Staphylococcus aureus Bacteria in a Hollow Fiber Infection Model.

scientific article published on 27 March 2018

Differential activation of beta 1-, beta 2- and beta 3-adrenoceptors by catecholamines in white and brown adipocytes.

scientific article published on January 1995

Dominant plasmids carrying extended spectrum β-lactamases blaCTX-M genes in genetically diverse Escherichia coli from slaughterhouse and urban wastewaters.

scientific article

Dynamic interactions between cephalexin and macrophages on different Staphylococcus aureus inoculum sizes: a tripartite in vitro model

scientific article published on 07 January 2021

Early Inoculation of Microbial Suspension in Suckling Piglets Affects the Transmission of Maternal Microbiota and the Associated Antibiotic Resistance Genes

scientific article published on 13 October 2020

Effects of altered plasma alpha1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis.

scientific article published in June 2002

Emergence of resistant Klebsiella pneumoniae in the intestinal tract during successful treatment of Klebsiella pneumoniae lung infection in rats

scientific article

En Route towards European Clinical Breakpoints for Veterinary Antimicrobial Susceptibility Testing: A Position Paper Explaining the VetCAST Approach.

scientific article published on 15 December 2017

Endectocide exchanges between grazing cattle after pour-on administration of doramectin, ivermectin and moxidectin

scientific article published in October 2004

Enrofloxacin and marbofloxacin in horses: comparison of pharmacokinetic parameters, use of urinary and metabolite data to estimate first-pass effect and absorbed fraction

scientific article

Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration

scientific article published on 01 October 2007

Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates

scientific article published on 01 January 1996

Free drug fraction vs free drug concentration: a matter of frequent confusion

scientific article published on 01 December 2002

GRF treatment of late pregnant ewes alters maternal and fetal somatotropic axis activity

scientific article published on April 1, 1991

Impact of Low and High Doses of Marbofloxacin on the Selection of Resistant Enterobacteriaceae in the Commensal Gut Flora of Young Cattle: Discussion of Data from 2 Study Populations.

scientific article

Impact of Timing and Dosage of a Fluoroquinolone Treatment on the Microbiological, Pathological, and Clinical Outcomes of Calves Challenged with Mannheimia haemolytica.

scientific article published on 2 March 2016

Impact of early versus later fluoroquinolone treatment on the clinical; microbiological and resistance outcomes in a mouse-lung model of Pasteurella multocida infection

scientific article

In vitro Degradation of Antimicrobials during Use of Broth Microdilution Method Can Increase the Measured Minimal Inhibitory and Minimal Bactericidal Concentrations

scientific article published on 21 December 2016

Infection-stage adjusted dose of beta-lactams for parsimonious and efficient antibiotic treatments: A Pasteurella multocida experimental pneumonia in mice

scientific article

Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model.

scientific article published on 8 September 2009

Interpreting bisphenol a absorption in the canine oral cavity: Gayrard et al. Respond

scientific article published on November 2013

Intestinal secretion is a major route for parent ivermectin elimination in the rat.

scientific article

Is Blood a Good Indicator for Detecting Antimicrobials in Meat? Evidence for the Development of In Vivo Surveillance Methods

scientific article published on 12 April 2020

Laparoscopic-assisted colopexy and sterilization in male dogs: short-term results and physiologic consequences

scientific article published on 26 April 2011

Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients?

scientific article published on 01 July 2019

Licking behaviour induces partial anthelmintic efficacy of ivermectin pour-on formulation in untreated cattle.

scientific article published on 11 January 2011

Lipolytic effects of beta 1-, beta 2-, and beta 3-adrenergic agonists in white adipose tissue of mammals

scientific article published on 01 May 1998

Low or high doses of cefquinome targeting low or high bacterial inocula cure Klebsiella pneumoniae lung infections but differentially impact the levels of antibiotic resistance in fecal flora

scientific article

Mixing of Shiga toxin-producing and enteropathogenic Escherichia coli in a wastewater treatment plant receiving city and slaughterhouse wastewater

scientific article published on 29 December 2017

Modelling the loss of metabolic capacities of cultured hepatocytes: application to measurement of Michaelis-Menten kinetic parameters in in vitro systems.

scientific article published in October 2002

New antibiotics in orphan food-producing animals: what is the responsibility of a journal regarding good veterinary practice?

scientific article published on 12 June 2008

Persistence and prevalence of pathogenic and extended-spectrum beta-lactamase-producing Escherichia coli in municipal wastewater treatment plant receiving slaughterhouse wastewater.

scientific article published on 3 May 2013

Pharmacokinetic/pharmacodynamic analysis of the influence of inoculum size on the selection of resistance in Escherichia coli by a quinolone in a mouse thigh bacterial infection model

scientific article published on June 2009

Pharmacokinetic/pharmacodynamic assessment of the effects of parenteral administration of a fluoroquinolone on the intestinal microbiota: comparison of bactericidal activity at the gut versus the systemic level in a pig model.

scientific article published on 19 August 2013

Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs

scientific article published on 01 September 2005

Pharmacokinetics of Ertapenem in Sheep (Ovis aries) with Experimentally Induced Urinary Tract Infection

scientific article published on 03 October 2019

Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration.

scientific article

Pharmacokinetics of marbofloxacin in horses.

scientific article published in July 2002

Plasma clearance

scientific article

Population Pharmacokinetic Study of Cefazolin Used Prophylactically in Canine Surgery for Susceptibility Testing Breakpoint Determination

scientific article published on 09 October 2018

Population pharmacokinetics of marbofloxacin in horses: preliminary analysis.

scientific article published in October 2004

Prediction of human prenatal exposure to bisphenol A and bisphenol A glucuronide from an ovine semi-physiological toxicokinetic model.

scientific article published on 10 November 2017

Pregnancy modifies the alpha2-beta-adrenergic receptor functional balance in rabbit fat cells

scientific article published on 01 February 1999

Prevalence of Beta-Lactam and Quinolone/Fluoroquinolone Resistance in Enterobacteriaceae From Dogs in France and Spain-Characterization of ESBL/pAmpC Isolates, Genes, and Conjugative Plasmids

scientific article published on 30 August 2019

Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses

scientific article published on 20 December 2020

Rebuttal to the reaction of the EGGVP to the review article 'the consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics'

scientific article published on 01 December 2014

Should licking behavior be considered in the bioavailability evaluation of transdermal products?

scientific article published on 01 April 2012

Species differences in pharmacokinetics and pharmacodynamics.

scientific article published on January 2010

The adrenocorticotropin stimulation test: contribution of a physiologically based model developed in horse for its interpretation in different pathophysiological situations encountered in man

scientific article published on 08 June 2006

The consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics.

scientific article published on 29 May 2013

The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics

scientific article

The pharmacokinetic/pharmacodynamic paradigm for antimicrobial drugs in veterinary medicine: Recent advances and critical appraisal

scientific article published on 21 October 2020

The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms

scientific article published on December 1, 1992

Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs

scientific article published in February 2014

Variability of the Ability of Complex Microbial Communities to Exclude Microbes Carrying Antibiotic Resistance Genes in Rabbits

scientific article published on 02 July 2019

Veterinary Medicine Needs New Green Antimicrobial Drugs

scientific article

Why Were More Than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One?

scientific article published on 01 January 2020

[Lipid mobilization, physiopathological and pharmacological aspects]

scientific article published on 01 January 1995

beta-Adrenergic control of lipolysis in primate white fat cells: a comparative study with nonprimate mammals

scientific article published on 01 July 1994