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List of works by Pilar Blancafort

A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer

scientific article published in 2022

Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System

scientific article published on 14 December 2018

Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

scientific article

Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps).

scientific article

Aurantoside C Targets and Induces Apoptosis in Triple Negative Breast Cancer Cells

scientific article published on 01 October 2018

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer ⬇️

scientific article published on February 12, 2013

Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors.

scientific article published on 11 January 2013

Breastmilk is a novel source of stem cells with multilineage differentiation potential.

scientific article

Cisplatin induces differentiation of breast cancer cells

scientific article published on 3 June 2013

Crambescidin 800, Isolated from the Marine Sponge Monanchora viridis, Induces Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells

scientific article

Designing transcription factor architectures for drug discovery.

scientific article published on 31 August 2004

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

scientific article

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

scientific article

Epigenome engineering in cancer: fairytale or a realistic path to the clinic?

scientific article

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

scientific article

Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland

scientific article published on 11 April 2013

Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

article

Gene expression in breastmilk cells is associated with maternal and infant characteristics.

scientific article

Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

scientific article published on 27 September 2011

Genetic reprogramming of tumor cells by zinc finger transcription factors

scientific article published on 4 August 2005

Hallmarks of cancer: The CRISPR generation

scientific article published on 9 February 2018

Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer

scientific article published on 01 September 2020

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

scientific article

Long live the stem cell: the use of stem cells isolated from post mortem tissues for translational strategies

scientific article

Modulation of drug resistance by artificial transcription factors.

scientific article

Non-viral Methodology for Efficient Co-transfection

scientific article published in January 2018

Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.

scientific article

PolI-driven integrative expression vectors for yeast

scientific article published on 01 July 1997

Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

scientific article published on 21 October 2019

Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.

scientific article published in July 2004

Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors

scientific article published on 23 October 2006

Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation

scientific article published on 21 December 2015

Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)

scientific article published on February 2011

Remodeling genomes with artificial transcription factors (ATFs).

scientific article published on January 2010

Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.

scientific article published on May 2008

Scanning the human genome with combinatorial transcription factor libraries.

scientific article

Sensitizing basal-like breast cancer to chemotherapy using nanoparticles conjugated with interference peptide.

scientific article published on 19 April 2016

Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells.

scientific article

Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer

scientific article

Suppression of breast tumor growth and metastasis by an engineered transcription factor

scientific article published in 2011

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA.

scientific article published on 27 January 2017

Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy

scientific article published on 11 December 2012

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

scientific article

Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors

scientific article

The CRISPR road: from bench to bedside on an RNA-guided path.

scientific article

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

scientific article published on 26 March 2021

The recognition of a noncanonical RNA base pair by a zinc finger protein.

scientific article

Triple-hit therapeutic approach for triple negative breast cancers using docetaxel nanoparticles, EN1-iPeps and RGD peptides

scientific article published on 02 May 2019

Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

scientific article published on 03 August 2018

Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers

scientific article published on 27 June 2019

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system

scientific article published on 09 August 2016

Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules

scientific article

Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing

scientific article published in January 2018

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