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List of works by Alan Lyons

A Devil of a Transmissible Cancer

scientific article published on 01 April 2020

A monoclonal antibody to a human mast cell/myeloid leukaemia-specific antigen binds to normal haemopoietic progenitor cells and inhibits colony formation in vitro

scientific article published on 01 January 1988

A second transmissible cancer in Tasmanian devils

scientific article

Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

scientific article published on 19 January 2018

Acquisition of immune function during the development of the Langerhans cell network in neonatal mice

scientific article published in May 2001

Alternative pathways of apoptosis induced by methylprednisolone and valinomycin analyzed by flow cytometry

scientific article published on 01 October 1993

An isolate of Haemophilus haemolyticus produces a bacteriocin-like substance that inhibits the growth of nontypeable Haemophilus influenzae.

scientific article published on 24 February 2017

An oral bait vaccination approach for the Tasmanian devil facial tumor diseases

scientific article published on 23 January 2020

Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution.

scientific article

Are murine marginal-zone macrophages the splenic white pulp analog of high endothelial venules?

scientific article published on 01 November 1995

Assessment of snapper (Pagrus auratus) natural IgM binding to bromelain treated sheep erythrocytes

scientific article published on 01 January 2005

B cell differentiation and isotype switching is related to division cycle number

scientific article

Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4.

scientific article

Comparative Analysis of Immune Checkpoint Molecules and Their Potential Role in the Transmissible Tasmanian Devil Facial Tumor Disease.

scientific article

Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo

scientific article

Dasatinib suppresses in vitro natural killer cell cytotoxicity

scientific article published in April 2008

Demonstration of immune responses against devil facial tumour disease in wild Tasmanian devils.

scientific article published on October 2016

Determination of lymphocyte division by flow cytometry

scientific article

Discrete subpopulations, defined by CD45 isoforms, coexist within the leukaemic cells of B-chronic lymphocytic leukaemia patients

scientific article published on 01 January 1991

Divided we stand: tracking cell proliferation with carboxyfluorescein diacetate succinimidyl ester

scientific article

Drug-interaction studies evaluating T-cell proliferation reveal distinct activity of dasatinib and imatinib in combination with cyclosporine A.

scientific article published on 19 April 2012

Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages

scientific article published on 27 August 2019

Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations

scientific article

Flow cytometric analysis of cell division by dilution of CFSE and related dyes

scientific article

Flow cytometric analysis of cell division by dye dilution

scientific article

Heat shock proteins expressed in the marsupial Tasmanian devil are potential antigenic candidates in a vaccine against devil facial tumour disease

scientific article published on 27 April 2018

Human Flt-3 ligand-mobilized dendritic cells require additional activation to drive effective immune responses

article

Human interleukin-3 inhibits the binding of granulocyte-macrophage colony-stimulating factor and interleukin-5 to basophils and strongly enhances their functional activity

scientific article published on 01 October 1990

Human myeloid differentiation antigens identified by monoclonal antibodies to the myelomonocytic leukemia cell line RC-2A.

scientific article published in April 1988

Imatinib inhibits the functional capacity of cultured human monocytes.

scientific article published in February 2005

Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors

scientific article published in September 2003

Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release.

scientific article published on 19 February 2018

Immunology of a Transmissible Cancer Spreading among Tasmanian Devils

scientific article

In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CML.

scientific article published on 14 June 2005

Inhibition of c-fms by imatinib: expanding the spectrum of treatment.

scientific article published on 28 July 2005

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

scientific article

Maternal exposure to particulate matter alters early post-natal lung function and immune cell development.

scientific article published on 5 April 2018

Mitogen-activated Tasmanian devil blood mononuclear cells kill devil facial tumour disease cells

scientific article published on 19 April 2016

Modulation of lymphocyte migration to the murine spleen after marginal zone macrophage phagocytosis of blood-borne particulate material

scientific article

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

scientific article published on 02 April 2021

Natural killer cell mediated cytotoxic responses in the Tasmanian devil

scientific article

PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment

scientific article published on 09 December 2016

Pertussis toxin pretreatment alters the in vivo cell division behaviour and survival of B lymphocytes after intravenous transfer

scientific article published on 01 February 1997

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) acts as a regulator of B-cell development, B-cell antigen receptor (BCR)-mediated activation, and autoimmune disease

scientific article published on 01 July 2002

Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils

scientific article published on 9 March 2017

Resistance to c-KIT kinase inhibitors conferred by V654A mutation

scientific article published on 01 March 2007

Simultaneous analysis of immunophenotype and apoptosis of murine thymocytes by single laser flow cytometry

scientific article

Snapper (Pagrus auratus) leucocyte proliferation is synergistically enhanced by simultaneous stimulation with LPS and PHA.

scientific article

Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils

scientific article published on January 1990

Studies on the differentiation of the human myelomonocytic cell line RC-2A in response to lymphocyte-derived factors

scientific article published on 01 January 1987

The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines

scientific article

The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro

scientific article published on 18 April 2008

The absence of TNF permits myeloid Arginase 1 expression in experimental L. monocytogenes infection

scientific article published on 16 May 2017

The effect of recombinant cytokines on the proliferative potential and phenotype of cells of the human myelomonocytic leukaemia line, RC-2A

scientific article published on 01 January 1988

The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

scientific article

The importance of efficacy and partial agonism in evaluating models of B lymphocyte activation.

scientific article published on January 1997

The toll-like receptor ligands Hiltonol® (polyICLC) and imiquimod effectively activate antigen-specific immune responses in Tasmanian devils (Sarcophilus harrisii).

scientific article

Toll-like receptor signaling is functional in immune cells of the endangered Tasmanian devil

scientific article

Tracing the rise of malignant cell lines: Distribution, epidemiology and evolutionary interactions of two transmissible cancers in Tasmanian devils

scientific article published on 28 June 2019

Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells.

scientific article published on 23 March 2018

Two Decades of the Impact of Tasmanian Devil Facial Tumor Disease

scientific article published on 01 December 2018

Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii)

scientific article published on 02 August 2019