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List of works by Michael Zaugg

2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells

scientific article published on 20 October 2015

Accidental pleural puncture by a thoracic epidural catheter.

scientific article published in January 1998

Acute normovolemic hemodilution: physiology, limitations, and clinical use.

scientific article published on December 2003

Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply

scientific article

Adrenergic receptor genotype but not perioperative bisoprolol therapy may determine cardiovascular outcome in at-risk patients undergoing surgery with spinal block: the Swiss Beta Blocker in Spinal Anesthesia (BBSA) study: a double-blinded, placebo-

scientific article published in July 2007

Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats

scientific article published on August 2017

Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms.

scientific article published on October 2003

Anaesthetics and cardiac preconditioning. Part II. Clinical implications.

scientific article published on October 2003

Anesthetic cardioprotection in clinical practice from proof-of-concept to clinical applications.

scientific article published on January 2014

Antiproliferative effects of local anesthetics on mesenchymal stem cells: potential implications for tumor spreading and wound healing.

scientific article published in April 2012

Beneficial effects from beta-adrenergic blockade in elderly patients undergoing noncardiac surgery.

scientific article published in December 1999

Beta-adrenergic receptor subtypes differentially affect apoptosis in adult rat ventricular myocytes

scientific article published on 01 July 2000

Beta3-adrenergic receptor subtype signaling in senescent heart: nitric oxide intoxication or "endogenous" beta blockade for protection?

scientific article published on 01 December 2008

Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy

scientific article published on 16 July 2013

Cellular mechanisms in sympatho-modulation of the heart.

scientific article published on 14 May 2004

Choice of Lipid Emulsion Determines Inflammation of the Gut-Liver Axis, Incretin Profile, and Insulin Signaling in a Murine Model of Total Parenteral Nutrition

scientific article published on 30 July 2020

Comment on Kolwicz et al. Enhancing Cardiac Triacylglycerol Metabolism Improves Recovery From Ischemic Stress. Diabetes 2015;64:2817-2827.

scientific article

Daytime variations in perioperative myocardial injury

Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humans.

scientific article published in June 2008

Differential Effects of Anesthetics and Opioid Receptor Activation on Cardioprotection Elicited by Reactive Oxygen Species-Mediated Postconditioning in Sprague-Dawley Rat Hearts.

scientific article published on 15 December 2017

Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes.

scientific article published on 6 January 2010

Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat.

scientific article published on 14 January 2014

Enhanced glucose uptake via GLUT4 fuels recovery from calcium overload after ischaemia-reperfusion injury in sevoflurane- but not propofol-treated hearts.

scientific article published on 6 April 2011

External irradiation of macroinvasive pituitary adenomas with telecobalt: a retrospective study with long-term follow-up in patients irradiated with doses mostly of between 40-45 Gy.

scientific article published on June 1995

Fatal air embolism in an airplane passenger with a giant intrapulmonary bronchogenic cyst

scientific article published on 01 May 1998

Gene regulatory control of myocardial energy metabolism predicts postoperative cardiac function in patients undergoing off-pump coronary artery bypass graft surgery: inhalational versus intravenous anesthetics

scientific article

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

scientific article published on 3 December 2002

Genetic modulation of adrenergic activity in the heart and vasculature: implications for perioperative medicine.

scientific article

Genomics in cardiac metabolism.

scientific article published on 07 March 2008

Heart rate control and ischemia

scientific article published on 01 September 1999

How often should we perform arterial blood gas analysis during thoracoscopic surgery?

scientific article published in December 2007

Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury.

scientific article published on 24 October 2012

Inhibition of LINE-1 expression in the heart decreases ischemic damage by activation of Akt/PKB signaling.

scientific article published on 17 January 2006

Integration of calcium with the signaling network in cardiac myocytes.

scientific article published on 12 June 2006

Is protection by inhalation agents volatile? Controversies in cardioprotection.

scientific article published in November 2007

Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway.

scientific article

Isoflurane postconditioning prevents opening of the mitochondrial permeability transition pore through inhibition of glycogen synthase kinase 3beta.

scientific article

Letter by Zaugg and Lucchinetti regarding article, "Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".

scientific article published in June 2013

Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling

scientific article

Molecular evidence of late preconditioning after sevoflurane inhalation in healthy volunteers.

scientific article published in September 2007

New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics.

scientific article published on August 2006

Novel lipid emulsion for total parenteral nutrition based on 18-carbon n–3 fatty acids elicits a superior immunometabolic phenotype in a murine model compared with standard lipid emulsions

scientific article published in 2022

Patterns of changes in arterial PO2 during one-lung ventilation: a comparison between patients with severe pulmonary emphysema and patients with preserved lung function

scientific article

Perioperative organ protection. Preface

scientific article published on 01 March 2008

Phosphoproteome analysis of isoflurane-protected heart mitochondria: phosphorylation of adenine nucleotide translocator-1 on Tyr194 regulates mitochondrial function.

scientific article

Postconditioning with Intralipid emulsion protects against reperfusion injury in post-infarct remodeled rat hearts by activation of ROS-Akt/Erk signaling.

scientific article published on June 2017

Pragmatic treatment versus elaborative but incomplete testing: a Hobson's choice?

scientific article published on 01 October 2007

Preconditioning by isoflurane retains its protection against ischemia-reperfusion injury in postinfarct remodeled rat hearts.

scientific article published in January 2008

Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study.

scientific article published in June 2003

Preconditioning with sevoflurane decreases PECAM-1 expression and improves one-year cardiovascular outcome in coronary artery bypass graft surgery.

scientific article published on 19 November 2004

Propofol (Diprivan®) and Intralipid® exacerbate insulin resistance in type-2 diabetic hearts by impairing GLUT4 trafficking.

scientific article published in February 2015

Remote Ischemic Preconditioning Is Redundant in Patients Undergoing Coronary Artery Bypass Graft Surgery Who Are Already Protected by Volatile Anesthetics ⬇️

scientific article published on March 2, 2012

Remote Ischemic Preconditioning in Cardiac Surgery--Ineffective and Risky?

scientific article published on 05 October 2015

Remote ischemic preconditioning applied during isoflurane inhalation provides no benefit to the myocardium of patients undergoing on-pump coronary artery bypass graft surgery: lack of synergy or evidence of antagonism in cardioprotection?

scientific article

Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans.

scientific article published in February 2007

Sevoflurane--compared with propofol-based anesthesia reduces the need for inotropic support in patients undergoing abdominal aortic aneurysm repair: evidence of cardioprotection by volatile anesthetics in noncardiac surgery.

scientific article published in May 2014

Signaling and cellular mechanisms in cardiac protection by ischemic and pharmacological preconditioning ⬇️

scientific article published on January 1, 2003

Substantial changes in arterial blood gases during thoracoscopic surgery can be missed by conventional intermittent laboratory blood gas analyses

scientific article published on 01 September 1998

TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.

scientific article published on 8 August 2016

The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases

scientific article published in 2014

Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria

scientific article

Unraveling Interactions Between Anesthetics and the Endothelium: Update and Novel Insights.

scientific article

Video-assisted thoracoscopic volume reduction surgery in patients with diffuse pulmonary emphysema: gas exchange and anesthesiological management.

scientific article published in April 1997

Volatile anesthetics mimic cardiac preconditioning by priming the activation of mitochondrial K(ATP) channels via multiple signaling pathways.

scientific article

[Cardioprotection in the perioperative phase in non-cardiac procedures]

scientific article published on 01 June 2000

[Strategies for perioperative sympatho-modulation]

scientific article published on 01 April 2005

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