List of works - Yuesheng Zhang

5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder.

scientific article published on 11 December 2008

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

scientific article

A plasma proteolysis pathway comprising blood coagulation proteases

scientific article published on 7 February 2016

A recombinant human protein targeting HER2 overcomes drug resistance in HER2-positive breast cancer

scientific article published on 01 January 2019

A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway

scientific article

Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation.

scientific article

Allyl isothiocyanate as a cancer chemopreventive phytochemical.

scientific article

Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion ⬇️

scientific article published on October 1, 2010

Alternation of neurofilaments in immune-mediated injury of spinal cord motor neurons.

scientific article published on 29 July 2008

An improved liquid chromatography-tandem mass spectrometry method for the quantification of 4-aminobiphenyl DNA adducts in urinary bladder cells and tissues.

scientific article published on 10 November 2009

Anticoagulants inhibit proteolytic clearance of plasma amyloid beta.

scientific article published on 27 December 2017

Antimutagenic effect of garlic (Allium sativum L.) on 4NQO-induced mutagenesis in Escherichia coli WP2.

scientific article

Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype

scientific article published on 01 May 2004

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

scientific article

Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action.

scientific article published in November 2004

Chemoprotection against cancer by isothiocyanates and glucosinolates.

scientific article published on August 1996

Cruciferous vegetables, isothiocyanates, and prevention of bladder cancer

scientific article

Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells.

scientific article

Dithiolethiones for cancer chemoprevention: where do we stand?

scientific article

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.

scientific article published on 06 June 2016

Effects of cooking methods on total isothiocyanate yield from cruciferous vegetables

scientific article published on 09 September 2020

Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk.

scientific article

Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: critical nature of in vivo bioassay

scientific article published on 01 January 2006

Expression and regulation of glutathione S-transferase P1-1 in cultured human epidermal cells.

scientific article published on December 2002

Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.

scientific article

Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth

scientific article

Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts.

scientific article published on December 2006

Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant

scientific article published on May 2015

Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.

scientific article published on 24 December 2008

Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

scientific article published on October 1995

Isothiocyanates in the chemoprevention of bladder cancer.

scientific article published on April 2004

Mechanism of chemical activation of Nrf2

scientific article

Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes.

scientific article published in October 1998

Mercurials and Dimercaptans: Synergism in the Induction of Chemoprotective Enzymes

scientific article published on 01 January 1995

Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells.

scientific article published on August 2005

No association of NAD(P)H quinone oxidoreductase 1 expression with p53 expression or tumour outcome in patients with superficial and minimally invasive urothelial bladder cancers.

scientific article published in August 2008

Nrf2 amplifies oxidative stress via induction of Klf9.

scientific article

Organ-specific exposure and response to sulforaphane, a key chemopreventive ingredient in broccoli: implications for cancer prevention.

scientific article published on 2 April 2012

Oxidative stress in immune-mediated motoneuron destruction.

scientific article

PEPD is a pivotal regulator of p53 tumor suppressor

scientific article published on 12 December 2017

Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism.

scientific article published in November 2004

Prevention of glutamate excitotoxicity in motor neurons by 5,6-dihydrocyclopenta-1,2-dithiole-3-thione: implication to the development of neuroprotective drugs

scientific article published on 01 July 2007

Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling

scientific article published on 4 December 2012

Quantitative Determination of Isothiocyanates, Dithiocarbamates, Carbon Disulfide, and Related Thiocarbonyl Compounds by Cyclocondensation with 1,2-Benzenedithiol

scientific article published on 01 August 1996

Recent technical and biological development in the analysis of biomarker N-deoxyguanosine-C8-4-aminobiphenyl.

scientific article published on 24 April 2018

Selected isothiocyanates rapidly induce growth inhibition of cancer cells.

scientific article published on October 2003

Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols

scientific article published on 01 August 1992

Strong impact of sulfotransferases on DNA adduct formation by 4-aminobiphenyl in bladder and liver in mice

scientific article published on 10 October 2018

Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates.

scientific article published on 19 June 2008

Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues ⬇️

scientific article published on September 1, 2010

Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.

scientific article

Synthesis, biological evaluation, and structure-activity relationships of dithiolethiones as inducers of cytoprotective phase 2 enzymes.

scientific article

The Be-Well Study: a prospective cohort study of lifestyle and genetic factors to reduce the risk of recurrence and progression of non-muscle-invasive bladder cancer

scientific article published on 17 January 2019

The electrophile counterattack response: protection against neoplasia and toxicity.

scientific article

The inverse relationship between bladder and liver in 4-aminobiphenyl-induced DNA damage.

scientific article

The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates.

scientific article published on 10 November 2011

The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer

scientific article (publication date: 30 November 2011)

Understanding the gender disparity in bladder cancer risk: the impact of sex hormones and liver on bladder susceptibility to carcinogens.

scientific article published on January 2013

c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent.

scientific article published on August 2006

List of works by Yuesheng Zhang

5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder.

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

A plasma proteolysis pathway comprising blood coagulation proteases

A recombinant human protein targeting HER2 overcomes drug resistance in HER2-positive breast cancer

A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway

Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation.

Allyl isothiocyanate as a cancer chemopreventive phytochemical.

Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion ⬇️

Alternation of neurofilaments in immune-mediated injury of spinal cord motor neurons.

An improved liquid chromatography-tandem mass spectrometry method for the quantification of 4-aminobiphenyl DNA adducts in urinary bladder cells and tissues.

Anticoagulants inhibit proteolytic clearance of plasma amyloid beta.

Antimutagenic effect of garlic (Allium sativum L.) on 4NQO-induced mutagenesis in Escherichia coli WP2.

Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

Cancer-preventive isothiocyanates: measurement of human exposure and mechanism of action.

Chemoprotection against cancer by isothiocyanates and glucosinolates.

Cruciferous vegetables, isothiocyanates, and prevention of bladder cancer

Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells.

Dithiolethiones for cancer chemoprevention: where do we stand?

Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D.

Effects of cooking methods on total isothiocyanate yield from cruciferous vegetables

Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk.

Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: critical nature of in vivo bioassay

Expression and regulation of glutathione S-transferase P1-1 in cultured human epidermal cells.

Identification of an unintended consequence of Nrf2-directed cytoprotection against a key tobacco carcinogen plus a counteracting chemopreventive intervention.

Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth

Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts.

Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant

Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.

Isothiocyanates as substrates for human glutathione transferases: structure-activity studies.

Isothiocyanates in the chemoprevention of bladder cancer.

Mechanism of chemical activation of Nrf2

Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes.

Mercurials and Dimercaptans: Synergism in the Induction of Chemoprotective Enzymes

Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells.

No association of NAD(P)H quinone oxidoreductase 1 expression with p53 expression or tumour outcome in patients with superficial and minimally invasive urothelial bladder cancers.

Nrf2 amplifies oxidative stress via induction of Klf9.

Organ-specific exposure and response to sulforaphane, a key chemopreventive ingredient in broccoli: implications for cancer prevention.

Oxidative stress in immune-mediated motoneuron destruction.

PEPD is a pivotal regulator of p53 tumor suppressor

Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism.

Prevention of glutamate excitotoxicity in motor neurons by 5,6-dihydrocyclopenta-1,2-dithiole-3-thione: implication to the development of neuroprotective drugs

Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling

Quantitative Determination of Isothiocyanates, Dithiocarbamates, Carbon Disulfide, and Related Thiocarbonyl Compounds by Cyclocondensation with 1,2-Benzenedithiol

Recent technical and biological development in the analysis of biomarker N-deoxyguanosine-C8-4-aminobiphenyl.

Selected isothiocyanates rapidly induce growth inhibition of cancer cells.

Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols

Strong impact of sulfotransferases on DNA adduct formation by 4-aminobiphenyl in bladder and liver in mice

Structure-activity relationships and organ specificity in the induction of GST and NQO1 by alkyl-aryl isothiocyanates.

Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues ⬇️

Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.

Synthesis, biological evaluation, and structure-activity relationships of dithiolethiones as inducers of cytoprotective phase 2 enzymes.

The Be-Well Study: a prospective cohort study of lifestyle and genetic factors to reduce the risk of recurrence and progression of non-muscle-invasive bladder cancer

The electrophile counterattack response: protection against neoplasia and toxicity.

The inverse relationship between bladder and liver in 4-aminobiphenyl-induced DNA damage.

The molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates.

The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer

Understanding the gender disparity in bladder cancer risk: the impact of sex hormones and liver on bladder susceptibility to carcinogens.

c-jun/AP-1 activation does not affect the antiproliferative activity of phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent.