Search filters

List of works by Jian Shi

A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms.

scientific article published on 24 August 2017

A Pharmacometabonomic Approach To Predicting Metabolic Phenotypes and Pharmacokinetic Parameters of Atorvastatin in Healthy Volunteers.

scientific article published on 28 July 2015

A sensitive liquid chromatography-tandem mass spectrometry method for the quantification of valacyclovir and its metabolite acyclovir in mouse and human plasma

scientific article published on 19 June 2018

Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability

scientific article published on 19 August 2019

Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms.

scientific article

CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors.

scientific article published on 16 June 2015

Chemoproteomic Identification of Serine Hydrolase RBBP9 as a Valacyclovir-Activating Enzyme

scientific article published on 30 March 2020

Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses

scientific article

Comparison of protein expression between human livers and the hepatic cell lines HepG2, Hep3B, and Huh7 using SWATH and MRM-HR proteomics: Focusing on drug-metabolizing enzymes.

scientific article published on 10 March 2018

Consequences of Phenytoin Exposure on Hepatic Cytochrome P450 Expression during Postnatal Liver Maturation in Mice

scientific article published on 08 June 2018

Crataegus Special Extract WS 1442 Effects on eNOS and microRNA 155

scientific article published on 16 April 2018

Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender.

scientific article published on 7 September 2016

Differences in metabolite profile between blood plasma and serum

scientific article published on 23 July 2010

Effect of biphenyl hydrolase-like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice

scientific article published on 17 August 2018

Ethanol Interactions With Dexmethylphenidate and dl-Methylphenidate Spheroidal Oral Drug Absorption Systems in Healthy Volunteers.

scientific article

GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.

scientific article published on 6 March 2013

Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages

scientific article

Metabolic Perturbation and Potential Markers in Patients with Esophageal Cancer.

scientific article

Metabolic phenotype of rats exposed to heroin and potential markers of heroin abuse.

scientific article published on 27 July 2012

Metabolic shifts induced by human H460 cells in tumor-bearing mice.

scientific article published on 3 July 2015

Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells

scientific article published on 20 March 2013

Metabolomics and its application to the evaluation of the efficacy and toxicity of traditional Chinese herb medicines.

scientific article published on 24 November 2015

Pharmacokinetic interactions between 20(S)-ginsenoside Rh2 and the HIV protease inhibitor ritonavir in vitro and in vivo.

scientific article published on 29 July 2013

Predicting Human Pharmacokinetics: Physiologically Based Pharmacokinetic Modeling and In Silico ADME Prediction in Early Drug Discovery

scientific article published on 01 February 2019

Prediction of the pharmacokinetic parameters of triptolide in rats based on endogenous molecules in pre-dose baseline serum

scientific article

Regulatory effects of genomic translocations at the human carboxylesterase-1 (CES1) gene locus.

scientific article published on 11 February 2016

Response to the Comments on "Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Proteomics Method"

scientific article published on 09 January 2019

Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation

scientific article published on 27 January 2016

Sensitive determination of 20(S)-protopanaxadiol in rat plasma using HPLC-APCI-MS: application of pharmacokinetic study in rats

scientific article

Targeted absolute quantitative proteomics with SILAC internal standards and unlabeled full-length protein calibrators (TAQSI)

scientific article published on 01 March 2016

The metabolic impact of methamphetamine on the systemic metabolism of rats and potential markers of methamphetamine abuse

scientific article published on 14 May 2014