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List of works by Kenan Garcia

A strategy for the selection of monovalent antibodies that span protein dimer interfaces

scientific article published on 06 August 2019

Accurate prediction of protein structures and interactions using a three-track neural network

scientific article

Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition ⬇️

scientific article published on 01 April 1998

Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins

scientific article published on 21 January 2022

Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development

scientific article published on 15 August 2017

Deploying synthetic coevolution and machine learning to engineer protein-protein interactions

scientific article published on 27 July 2023

Design of protein-binding proteins from the target structure alone

scientific article published on 24 March 2022

Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance

article

Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

scientific article published on 10 August 2020

Diversity‐oriented approaches for interrogating T‐cell receptor repertoire, ligand recognition, and function ⬇️

scientific article published on November 1, 2012

Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy

scientific article published on 13 August 2018

Engineering protein for X‐ray crystallography: The murine major histocompatibility complex class II molecule I‐Ad ⬇️

scientific article published on February 1, 1998

Immune receptor inhibition through enforced phosphatase recruitment

scientific article published on 21 October 2020

In vivo molecular imaging for immunotherapy using ultra-bright near-infrared-IIb rare-earth nanoparticles

scientific article published on 30 September 2019

Insights into immune structure, recognition, and signaling ⬇️

scientific article published on November 1, 2012

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity

scientific article published on 27 July 2020

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

scientific article published on 07 February 2020

Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

scientific article published on 07 February 2022

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.

scientific article published on 2 March 2017

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

scientific article published on 25 November 2020

Reconciling views on T cell receptor germline bias for MHC ⬇️

scientific article published on July 6, 2012

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

scientific article

Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies

scientific article published on 16 July 2021

Structural Architecture and Functional Evolution of Wnts ⬇️

scientific article published on August 14, 2012

Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation ⬇️

scientific article published on November 1, 2012

Structure and selectivity engineering of the M1 muscarinic receptor toxin complex

scientific article

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling

scientific article published on 07 August 2020

Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers.

scientific article

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex ⬇️

scientific article published on November 23, 2011

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

scientific article published on 06 December 2021

T-cell receptor peptide-MHC interactions: biological lessons from structural studies ⬇️

scientific article published on August 1, 1998

T-cell receptor structure and TCR complexes ⬇️

scientific article published on December 1, 1997

The composition and signaling of the IL-35 receptor are unconventional ⬇️

scientific article published on February 5, 2012

Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

scientific article

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

scientific article published on 8 June 2018

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