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List of works by Henry Lester

27 Recombinant adenovirus-mediated expression in nervous system of genes coding for ion channels and other molecules involved in synaptic function

scientific article published on January 1, 1998

A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes.

scientific article published in November 1997

A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists ⬇️

scientific article published on January 25, 2011

A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels.

scientific article

A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way.

scientific article

A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques.

scientific article

A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor.

scientific article published on 22 May 2008

A perturbed pK(a) at the binding site of the nicotinic acetylcholine receptor: implications for nicotine binding.

scientific article published in October 2002

A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart.

scientific article

A potpourri of plucked patches ⬇️

scientific article published on 01 December 1981

A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale

scientific article (publication date: March 2009)

A stereochemical test of a proposed structural feature of the nicotinic acetylcholine receptor.

scientific article

A unique P-region residue is required for slow voltage-dependent gating of a G protein-activated inward rectifier K+ channel expressed in Xenopus oocytes.

scientific article published in February 1996

ADP-ribosylation of membrane proteins in cholinergic nerve terminals

scientific article published on 01 April 1982

Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons

scientific article

Activation of adenylate cyclase from purified platelet membranes by prostaglandin E1 and its inhibition by L-epinephrine: mechanistic effects.

scientific article published on January 1982

Allosteric activation of the 5-HT3AB receptor by mCPBG.

scientific article

Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm.

scientific article

Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor.

scientific article

Amino acid residues that control pH modulation of transport-associated current in mammalian serotonin transporters.

scientific article

An angstrom scale interaction between plasma membrane ATP-gated P2X2 and alpha4beta2 nicotinic channels measured with fluorescence resonance energy transfer and total internal reflection fluorescence microscopy.

scientific article published in July 2005

An engineered glutamate-gated chloride (GluCl) channel for sensitive, consistent neuronal silencing by ivermectin.

scientific article published on 29 May 2013

An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating.

scientific article published on 24 October 2008

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor ⬇️

scientific article published on January 1, 1990

Analysis of sodium and potassium redistribution during sustained permeability increases at the innervated face of Electrophorus electroplaques ⬇️

scientific article published on December 1, 1978

Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons.

scientific article published in December 2003

Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel.

scientific article

At least two mRNA species contribute to the properties of rat brain A-type potassium channels expressed in Xenopus oocytes

article

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

scientific article

Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs

scientific article published on 17 January 2019

Binding Interactions with the Complementary Subunit of Nicotinic Receptors ⬇️

scientific article published on January 24, 2013

Both sodium channel II and IIA alpha subunits are expressed in rat brain.

scientific article published on October 1990

CNS localization of neuronal nicotinic receptors.

scientific article published on January 2006

Ca channels induced in Xenopus oocytes by rat brain mRNA

scientific article published on 01 March 1987

Caging proteins through unnatural amino acid mutagenesis.

scientific article published in January 2003

Cell-specific posttranslational events affect functional expression at the plasma membrane but not tetrodotoxin sensitivity of the rat brain IIA sodium channel alpha-subunit expressed in mammalian cells

scientific article published on January 1992

Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: Mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells ⬇️

scientific article published on May 17, 2011

Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors.

scientific article

Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.

scientific article

Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path.

scientific article

Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway.

scientific article published on October 2009

Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

scientific article

Cloning, expression, and localization of a rat brain high-affinity glycine transporter ⬇️

scientific article published on August 1, 1992

Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins.

scientific article published on February 2000

Codon optimization of Caenorhabditis elegans GluCl ion channel genes for mammalian cells dramatically improves expression levels.

scientific article published on March 2003

Colocalization of mu opioid receptors with GIRK1 potassium channels in the rat brain: an immunocytochemical study.

scientific article

Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques ⬇️

scientific article published on June 1, 1975

Conducting states of a mammalian serotonin transporter.

scientific article published in April 1994

Confirming the revised C-terminal domain of the MscL crystal structure.

scientific article published on 7 March 2008

Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation ⬇️

scientific article published on May 1, 1997

D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.

scientific article

Deletion of lynx1 reduces the function of α6* nicotinic receptors.

scientific article published on 5 December 2017

Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors.

scientific article published on 04 February 2019

Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge?

scientific article

Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes.

scientific article published on December 1994

Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula

scientific article

Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor.

scientific article

Dose-response of acetylcholine receptor channels opened by a flash-activated agonist in voltage-clamped rat myoballs.

scientific article

Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists.

scientific article

Early fluorescence signals detect transitions at mammalian serotonin transporters.

scientific article

Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report ⬇️

scientific article published on January 1, 1980

Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents.

scientific article published on 30 May 2012

Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons.

scientific article published in May 2006

Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons.

scientific article

Establishing an ion pair interaction in the homomeric rho1 gamma-aminobutyric acid type A receptor that contributes to the gating pathway.

scientific article

Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype.

scientific article published on 27 May 2009

Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes

scientific article published on August 1988

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers ⬇️

scientific article published on July 3, 1995

Experiments with photoisomerizable molecules at nicotinic acetylcholine receptors in cells and membrane patches from rat muscle

scientific article published on 01 January 1986

Expression and Circular Dichroism Studies of the Extracellular Domain of the α Subunit of the Nicotinic Acetylcholine Receptor ⬇️

scientific article published on October 10, 1997

Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus.

scientific article

Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without beta1 integrins.

scientific article published on January 2000

Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons

scientific article

Expression of functional sodium channels in stage II-III Xenopus oocytes.

scientific article

Expression of mRNA encoding voltage-dependent Ca channels in Xenopus oocytes. Review and progress report.

scientific article published on January 1989

Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes.

scientific article published in September 1987

Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain.

scientific article published on April 2009

Fast inhibition of inwardly rectifying K+ channels by multiple neurotransmitter receptors in oligodendroglia

scientific article published on 01 November 1994

Five ADNFLE Mutations Reduce the Ca2+ Dependence of the Mammalian α4β2 Acetylcholine Response ⬇️

scientific article published on May 16, 2003

Flash Decaging of Tyrosine Sidechains in an Ion Channel ⬇️

scientific article published on April 1, 1998

From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor ⬇️

scientific article published on October 13, 1998

Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells.

scientific article published in October 2003

Functional evaluation of key interactions evident in the structure of the eukaryotic Cys-loop receptor GluCl

scientific article

Functional expression of the heteromeric "olfactory" cyclic nucleotide-gated channel in the hippocampus: a potential effector of synaptic plasticity in brain neurons.

scientific article published in March 1997

Functional expression of the yeast alpha-factor receptor in Xenopus oocytes.

scientific article published in December 1989

Functional stoichiometry at the nicotinic receptor. The photon cross section for phase 1 corresponds to two bis-Q molecules per channel ⬇️

scientific article published on October 1, 1982

Functionally important aromatic-aromatic and sulfur-π interactions in the D2 dopamine receptor.

scientific article

Further evidence demonstrating that N-methyl-D-aspartate and kainate activate distinct ion channels.

scientific article

GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.

scientific article published in March 2005

GABA transporter-1 (GAT1)-deficient mice: differential tonic activation of GABAA versus GABAB receptors in the hippocampus.

scientific article published on 18 June 2003

Gamma-aminobutyric acid type A receptors modulate cAMP-mediated long-term potentiation and long-term depression at monosynaptic CA3-CA1 synapses

scientific article published on 10 April 2001

Gating transitions in bacterial ion channels measured at 3 microns resolution

scientific article (publication date: August 2004)

Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina

scientific journal article

Gi Irks GIRKs.

scientific article

Glutamate-101 is critical for the function of the sodium and chloride-coupled GABA transporter GAT-1

scientific article published on 01 August 1995

H+ permeation and pH regulation at a mammalian serotonin transporter.

scientific article published in April 1997

Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP ⬇️

scientific article published on September 13, 1994

Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.

scientific article published on September 2003

Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: evaluating suppression efficiency.

scientific article published on 13 August 2007

In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression.

scholarly article

In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system.

scientific article published in January 1998

Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor.

scientific article published in July 2001

Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.

scientific article published in April 2003

Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.

scientific article

International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels

scientific article (publication date: December 2003)

Intrinsic noise in cultured hippocampal neurons: experiment and modeling.

scientific article published on October 2004

Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide.

scientific article published in January 2003

Ion binding and permeation at the GABA transporter GAT1.

scientific article published in September 1996

Ion channel diseases of the central nervous system.

scientific article

Key binding interactions for memantine in the NMDA receptor.

scientific article published on 7 December 2012

Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination.

scientific article published in August 2001

Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally.

scientific article

Listening to neurotransmitter transporters.

scientific article published on November 1996

Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures.

scientific article

Long-range coupling in an allosteric receptor revealed by mutant cycle analysis

scientific article published on April 2009

Low molecular weight mRNA encodes a protein that controls serotonin 5-HT1c and acetylcholine M1 receptor sensitivity in Xenopus oocytes

scientific article

Lynx1 supports neuronal health in the mouse dorsal striatum during aging: an ultrastructural investigation.

scientific article

Mapping disulfide connectivity using backbone ester hydrolysis.

scientific article

Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward

scientific article

Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability

scientific article published on 12 April 2017

Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing

scientific article published on 01 November 2018

Modulation of a cloned mouse brain potassium channel.

scientific article

Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus.

scientific article

Multiplexed, high density electrophysiology with nanofabricated neural probes

scientific article (publication date: 2011)

Mutations affecting local anesthetic block of the nicotinic acetylcholine receptor ion channel

scientific article published on January 1, 1991

Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations ⬇️

scientific article published on September 1, 1992

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses ⬇️

scientific article published on April 14, 2011

Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds.

scientific article published on April 1999

New photoactivatable cyclic nucleotides produce intracellular jumps in cyclic AMP and cyclic GMP concentrations

scientific article published in Nature

New views of multi-ion channels.

scientific article published on February 1998

Nicotine binding to brain receptors requires a strong cation-pi interaction

scientific article

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors.

scientific article

Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.

scientific article published on 12 March 2009

Nicotine responses in hypersensitive and knockout alpha 4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice.

scientific article published on 21 August 2007

Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation

scientific article published in September 2007

Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior.

scientific article published on 4 November 2011

Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus

scientific article

Novel pore-lining residues in CFTR that govern permeation and open-channel block ⬇️

scientific article published on September 1, 1994

Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors.

scientific article

Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions.

scientific article published on December 2002

Numerical reconstruction of the quantal event at nicotinic synapses ⬇️

scientific article published on July 1, 1979

On-resin assembly of a linkerless lanthanide(III)-based luminescence label and its application to the total synthesis of site-specifically labeled mechanosensitive channels.

scientific article published in September 2004

Permeation properties of neurotransmitter transporters.

scientific article published on January 1994

Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

scientific article

Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.

scientific article published on March 2014

Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response.

scientific article

Photoactivatable drugs for nicotinic optopharmacology

Photoactivation and dissociation of agonist molecules at the nicotinic acetylcholine receptor in voltage-clamped rat myoballs.

scientific article published on August 1985

Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.

scientific article

Postsynaptic action of cobra toxin at the myoneural junction.

scientific article

Postsynaptic mechanisms are essential for forskolin-induced potentiation of synaptic transmission.

scientific article published on 4 January 2006

Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor.

scientific article published on 14 February 2012

Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor

scientific article published on 18 October 2013

Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids.

scholarly article

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

scientific article

Psychiatric drugs bind to classical targets within early exocytotic pathways: therapeutic effects

scientific article published on 06 July 2012

RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K+ channels ⬇️

scientific article published on September 16, 1997

ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons.

scientific article published on August 2000

Random mutagenesis of G protein alpha subunit G(o)alpha. Mutations altering nucleotide binding.

scientific article published in October 1993

Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes

scientific article published in April 1987

Rat brain expresses a heterogeneous family of calcium channels.

scientific article

Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations

scientific article

Receptors that couple to 2 classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes

scientific article published on January 1, 1993

Regions of beta 4.beta 2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors.

scientific article

Relaxation measurements on the acetylcholine receptor ⬇️

scientific article published on September 1, 1975

Requirement of a critical period of GABAergic receptor blockade for induction of a cAMP-mediated long-term depression at CA3-CA1 synapses.

scientific article published in July 2003

Response of acetylcholine receptors to rapid photochemically produced increases in agonist concentration

scientific article published in Nature

Role of voltage-sensitive receptors in nicotinic transmission ⬇️

scientific article published on March 1, 1978

Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1.

scientific article published on May 1997

Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors

scientific article published on 30 March 2017

Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels.

scientific article published in September 2002

Selective ligand behaviors provide new insights into agonist activation of nicotinic acetylcholine receptors.

scientific article

Serotonin and protein kinase C modulation of a rat brain inwardly rectifying K+ channel expressed in xenopus oocytes.

scientific article published in January 1996

Single-channel properties of mouse—Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes ⬇️

scientific article published on June 1, 1991

Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors

scientific article published on January 2009

Single-molecule measurements calibrate green fluorescent protein surface densities on transparent beads for use with 'knock-in' animals and other expression systems.

scientific article

Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins ⬇️

scientific article published on October 1, 1997

Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells.

scientific article published in June 2003

Site-specific, photochemical proteolysis applied to ion channels in vivo.

scientific article published on September 1997

Slow and incomplete inactivations of voltage-gated channels dominate encoding in synthetic neurons.

scientific article

Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons.

scientific article

State-dependent cross-inhibition between transmitter-gated cation channels.

scientific article

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes.

scientific article published in February 1993

Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission ⬇️

scientific article published on April 1, 1992

Subtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptors

scientific article

Subunit stoichiometry of a heteromultimeric G protein-coupled inward-rectifier K+ channel.

scientific article

TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus.

scientific article published on 19 July 2017

The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane.

scientific article published on August 2013

The Response to Acetylcholine

scientific article published on February 1, 1977

The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7.

scientific article

The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function

scientific article

The inward rectifier potassium channel family.

scientific article published on June 1995

The kinetics of tubocurarine action and restricted diffusion within the synaptic cleft ⬇️

scientific article published on September 1, 1979

The mouse 5-HT1C receptor contains eight hydrophobic domains and is X-linked ⬇️

scientific article published on September 1, 1991

The permeation pathway of neurotransmitter-gated ion channels

scientific article published on January 1, 1992

The response to vagusstoff

scientific article published in Nature

The structural basis of function in Cys-loop receptors.

scientific article published on 20 September 2010

Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation.

scientific article

Transcriptional regulation by nicotine in dopaminergic neurons ⬇️

scientific article published on August 9, 2013

Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region

scientific article

Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes.

scientific article

Two neuronal nicotinic acetylcholine receptors, α4β4 and α7, show differential agonist binding modes.

scientific article published in August 2011

Two-compartment model for whole-cell data analysis and transient compensation.

scientific article

Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis.

scientific article published in October 2004

Unnatural amino acid mutagenesis in mapping ion channel function.

scientific article

Unnatural amino acid mutagenesis of the GABA(A) receptor binding site residues reveals a novel cation-pi interaction between GABA and beta 2Tyr97

scientific article published on January 2007

Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit.

scientific article

Use of stage II-III Xenopus oocytes to study voltage-dependent ion channels

scientific article published on January 1, 1992

Using mutant cycle analysis to elucidate long-range functional coupling in allosteric receptors.

scientific article

Vaccinia virus as vector to express ion channel genes

scientific article published on January 1, 1992

Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor.

scientific article

Variability of acute extracellular action potential measurements with multisite silicon probes.

scientific article

Variations in binding among several agonists at two stoichiometries of the neuronal, α4β2 nicotinic receptor ⬇️

scientific article published on July 9, 2012

Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes.

scientific article published in March 1994

Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques ⬇️

scientific article published on May 1, 1979

Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates

scientific article

Voltage-jump relaxation kinetics for wild-type and chimeric beta subunits of neuronal nicotinic receptors

scientific article

cis-3,3'-Bis-[alpha-(trimethylammonium)methyl]azobenzene (cis-Bis-Q). Purification and properties at acetylcholine receptors of Electrophorus electroplaques.

scientific article published on March 1983

α6* nicotinic acetylcholine receptor expression and function in a visual salience circuit.

scientific article

α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces.

scientific article

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