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List of works by John Briggs

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.

scientific article

A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

scientific article published on 5 December 2022

A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

preprint published on 28 February 2022

A new method to model membrane protein structure based on silent amino acid substitutions.

scientific article

A saposin-lipoprotein nanoparticle system for membrane proteins.

scientific article

A stable immature lattice packages IP for HIV capsid maturation

scientific article published in March 2021

A thermostable, closed SARS-CoV-2 spike protein trimer

scientific article published on 31 July 2020

A thermostable, closed, SARS-CoV-2 spike protein trimer

preprint published on 17 June 2020

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity

An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

scientific article

An organized co-assembly of clathrin adaptors is essential for endocytosis

scientific article

Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles

scientific article published on 22 July 2020

Arrangements of proteins at reconstituted synaptic vesicle fusion sites depend on membrane separation

scientific article published on 29 August 2020

Classification and three-dimensional reconstruction of unevenly distributed or symmetry mismatched features of icosahedral particles.

scientific article published on 19 April 2005

Clathrin modulates vesicle scission, but not invagination shape, in yeast endocytosis

scientific article published on 24 June 2016

Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission

scientific article

Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25

scientific article published on 01 July 2020

Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release

scientific article

Computational identification of novel amino-acid interactions in HIV Gag via correlated evolution.

scientific article

Computational model of membrane fission catalyzed by ESCRT-III.

scientific article

Conserved and variable features of Gag structure and arrangement in immature retrovirus particles

scientific article published on September 2010

Contrast transfer function correction applied to cryo-electron tomography and sub-tomogram averaging.

scientific article

Contribution of energy values to the analysis of global searching molecular dynamics simulations of transmembrane helical bundles.

scientific article published on June 2002

Convergence of experimental, computational and evolutionary approaches predicts the presence of a tetrameric form for CD3-zeta.

scientific article published in February 2002

Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core

scientific article published on 22 February 2022

Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core

preprint published on 7 June 2021

Correlated cryo-fluorescence and cryo-electron microscopy with high spatial precision and improved sensitivity

scientific article published on 11 November 2013

Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision

scientific article published on 3 January 2011

Correlative light and electron microscopy methods for the study of virus-cell interactions

scientific article published on 24 March 2016

Cryo electron tomography of native HIV-1 budding sites

scientific article

Cryo-Electron Tomography and Subtomogram Averaging.

scientific article

Cryo-electron microscopy of retroviruses

doctoral thesis by John A. G. Briggs

Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly

scientific article

Cryo-electron microscopy reveals conserved and divergent features of gag packing in immature particles of Rous sarcoma virus and human immunodeficiency virus.

scientific article published on 2 November 2005

Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ

scientific article published in August 2006

Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells

scientific article published in November 2011

Cryoelectron microscopy of mouse mammary tumor virus

scientific article published on March 2004

Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses

scientific article published on 24 August 2017

Determination of protein structure at 8.5A resolution using cryo-electron tomography and sub-tomogram averaging. Schur, F. K., Hagen, W. J. H., de Marco, A., Briggs, J. A. G. [J. Struct. Biol. 184 (2013) 394–400]

Determination of protein structure at 8.5Å resolution using cryo-electron tomography and sub-tomogram averaging.

scientific article

Directing traffic into the future

scientific article

Do lipid rafts mediate virus assembly and pseudotyping?

scientific article

Double-labelled HIV-1 particles for study of virus-cell interaction.

scientific article published on 9 November 2006

ENDOCYTOSIS. Endocytic sites mature by continuous bending and remodeling of the clathrin coat

scientific article published on June 2015

Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

scientific article published on 05 October 2020

Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4Å

scientific article

Electron tomography reveals the steps in filovirus budding

scientific article

Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals

scientific article published on 03 June 2020

FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P<sub>2</sub>-dependent switch

scientific article published on 29 April 2022

Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy

scientific article published on 14 May 2019

HIV-1-cellular interactions analyzed by single virus tracing.

scientific article

High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation

article published in the Proceedings of the National Academy of Sciences of the United States of America

High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding

scientific article published on 09 July 2019

Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.

scientific article published on 06 June 2016

Imaging cellular structure across scales with correlated light, superresolution, and electron microscopy.

scientific article published in March 2012

Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation

scientific article published on 01 January 2021

Immature HIV-1 lattice assembly dynamics are regulated by scaffolding from nucleic acid and the plasma membrane

scientific article published on 7 November 2017

Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging

scientific article

In vitro assembly of virus-like particles of a gammaretrovirus, the murine leukemia virus XMRV.

scientific article published on 16 November 2011

Induced maturation of human immunodeficiency virus.

scientific article published on 17 September 2014

Insights from reconstitution reactions of COPII vesicle formation using pure components and low mechanical perturbation

scientific article published on 01 July 2014

Maturation of the matrix and viral membrane of HIV-1

scientific article published on 6 August 2021

Maturation of the matrix and viral membrane of HIV-1

scientific article published on 23 September 2020

Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy

scientific article published on 28 January 2014

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

scientific article

Multibudded tubules formed by COPII on artificial liposomes

scientific article published on 17 June 2011

Multiple site-specific infrared dichroism of CD3-zeta, a transmembrane helix bundle

scientific article published in February 2002

New hardware and workflows for semi-automated correlative cryo-fluorescence and cryo-electron microscopy/tomography

scientific article

Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging.

scientific article published on 11 July 2013

Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging.

scientific article published on 24 February 2016

Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper

scientific article (publication date: 8 May 2003)

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.

scientific article

Plasma membrane reshaping during endocytosis is revealed by time-resolved electron tomography.

scientific article

Precise, correlated fluorescence microscopy and electron tomography of lowicryl sections using fluorescent fiducial markers.

scientific article

RNA and Nucleocapsid Are Dispensable for Mature HIV-1 Capsid Assembly

scientific article

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

scientific article published on 11 October 2017

Retrovirus maturation-an extraordinary structural transformation

scientific article

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes

scientific article

Role of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivity

scientific article (publication date: December 2012)

SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.

scientific article published on 3 February 2014

Strain and rupture of HIV-1 capsids during uncoating

scientific article published on 01 March 2022

Structural Analysis of the Roles of Influenza A Virus Membrane-Associated Proteins in Assembly and Morphology

scientific article published on 17 June 2015

Structural analysis of HIV-1 maturation using cryo-electron tomography

scientific article

Structural biology in situ—the potential of subtomogram averaging ⬇️

scientific article published on March 4, 2013

Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography

scientific article

Structural organization of authentic, mature HIV-1 virions and cores

scientific article published in April 2003

Structure and architecture of immature and mature murine leukemia virus capsids

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure and assembly of immature HIV

scholarly article

Structure and assembly of the Ebola virus nucleocapsid

scientific article published on 8 November 2017

Structure of a hexameric RNA packaging motor in a viral polymerase complex.

scientific article published on 7 October 2006

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses

scientific article published on 29 April 2019

Structure of the hexagonal surface layer on Caulobacter crescentus cells

scientific article published on 18 April 2017

Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

scientific article

Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy

scientific article

Structure of the membrane-assembled retromer coat determined by cryo-electron tomography

scientific article published in Nature

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

scientific article published on 17 August 2020

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly

scientific article published on 27 January 2020

Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins

scientific article published on 06 January 2020

The HIV mutation browser: a resource for human immunodeficiency virus mutagenesis and polymorphism data

scientific article (publication date: December 2014)

The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

scientific article (publication date: 2006)

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer

scientific article published in January 2018

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer.

scientific article published in March 2018

The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly.

scientific article

The contributions of the actin machinery to endocytic membrane bending and vesicle formation

scientific article published on 10 April 2018

The molecular architecture of HIV.

scientific article published on July 2011

The native structure of the assembled matrix protein 1 of influenza A virus

scientific article published on 09 September 2020

The native structure of the full-length, assembled influenza A virus matrix protein, M1

scientific article published on 24 June 2020

The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin.

scientific article

The stoichiometry of Gag protein in HIV-1.

scientific article

The structure and flexibility of conical HIV-1 capsids determined within intact virions

scientific article

The structure of the COPI coat determined within the cell

scientific article published on 17 November 2017

The structure of the COPII transport-vesicle coat assembled on membranes

scientific article

The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions

scientific article

Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis

scientific article

Tubular endocytosis drives remodelling of the apical surface during epithelial morphogenesis in Drosophila

scientific article

VESICULAR TRANSPORT. A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly

scientific article

Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA

scientific article

Vesicle coats: structure, function, and general principles of assembly.

scientific article

Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition

scientific article

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