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List of works by Mitchell Guttman

A high-resolution map of human evolutionary constraint using 29 mammals

scientific article

A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals

scientific article published on 30 August 2012

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

scientific journal article

A protein assembly mediates Xist localization and gene silencing

scientific article published on 09 September 2020

Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

scientific article (publication date: May 2010)

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

scientific article (publication date: 12 March 2009)

Computational methods for transcriptome annotation and quantification using RNA-seq ⬇️

scientific article published on May 27, 2011

Development and evaluation of RNA-seq methods

Digital transcriptome profiling from attomole-level RNA samples

scientific article

Erratum: Corrigendum: Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

scholarly article published in Nature Biotechnology

Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs

scientific article published on 2 February 2016

High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection

scientific article published on 19 September 2020

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

scientific article published on 07 June 2018

Identifying novel constrained elements by exploiting biased substitution patterns

scientific article

Integrative genomics viewer ⬇️

scientific article published on January 1, 2011

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

scientific article

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

scientific article

Methods for comprehensive experimental identification of RNA-protein interactions

scientific article

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

scientific article

Publisher Correction: A protein assembly mediates Xist localization and gene silencing

scientific article published on 02 October 2020

Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

scientific article published in Nature

RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells

scientific article published in January 2018

RNA Function. RNA and dynamic nuclear organization

scientific article

RNA antisense purification (RAP) for mapping RNA interactions with chromatin

scientific article published on January 2015

RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites

scientific article

Re-evaluating the foundations of lncRNA-Polycomb function.

scientific article published on 15 March 2017

Response to Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing".

scientific article

Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins

scientific article published on 27 June 2013

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP).

scientific article

The NIH BD2K center for big data in translational genomics

scientific article

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

scientific article published in Nature

The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome

scientific article

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

scientific article

Transcriptional and epigenetic dynamics during specification of human embryonic stem cells

scientific article published on 09 May 2013

Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA.

scientific article

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

scientific article

m(6)A RNA methylation promotes XIST-mediated transcriptional repression

scientific article

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