List of works - Mark W Robinson

A comparative proteomics analysis of the egg secretions of three major schistosome species

scientific article published on 19 September 2020

A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides

scientific article

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase.

scientific article published on 7 August 2012

A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis.

scientific article

An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host.

scientific article published on 14 May 2009

Antimicrobial peptides: utility players in innate immunity.

scientific article published on 25 October 2012

Benzimidazole binding to Haemonchus contortus tubulin: a question of structure.

scientific article

Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation

scientific article (publication date: 2013)

Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini.

scientific article

Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

scientific article

Comparative analysis of the excretory–secretory proteome of the muscle larva of Trichinella pseudospiralis and Trichinella spiralis

scientific article published on 15 September 2006

Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules?

scientific article

Development of the vitellaria of the liver fluke, Fasciola hepatica in the rat host

scientific article published on 01 November 2001

Extracellular Vesicle Biogenesis in Helminths: More than One Route to the Surface?

scientific article

Extracellular vesicle-mediated communication in host-parasite interactions: insight from Fasciola hepatica.

scientific article published on May 2017

Fasciola gigantica: Comparison of the tegumental ultrastructure in newly excysted metacercariae and in vitro penetrated juvenile flukes indicates intracellular sources of molecules with vaccinal and immunomodulatory potential

scientific article published on 07 December 2018

Fasciola hepatica expresses multiple alpha- and beta-tubulin isotypes.

scientific article published on 14 February 2008

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective.

scientific article published on 02 December 2011

Fasciola hepatica: the therapeutic potential of a worm secretome.

scientific article published on 05 December 2012

Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3.

scientific article

Helminth defence molecules-immunomodulators designed by parasites!

scientific article

Helminth pathogen cathepsin proteases: it's a family affair.

scientific article published on 08 October 2008

Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development

scientific article published on 06 April 2013

Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host.

scientific article published on 10 January 2018

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae

scientific article published on 17 April 2013

Optimized conditions for the in vitro excystment of Calicophoron daubneyi metacercariae.

scientific article published on 14 December 2017

Paramphistomosis of Ruminants: An Emerging Parasitic Disease in Europe

scientific article

Profiling excretory/secretory proteins of Trichinella spiralis muscle larvae by two-dimensional gel electrophoresis and mass spectrometry

scientific article

Proteomic analysis of the excretory-secretory proteins of the Trichinella spiralis L1 larva, a nematode parasite of skeletal muscle.

scientific article

Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors.

scientific article

RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini.

scientific article published on May 2011

Response to Morley: The Influence of Climate on Survival of Paramphistome Metacercariae

scientific article

Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells.

scientific article published on 8 March 2018

Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

scientific article

Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse

scientific article

Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.

scientific article published on 17 October 2006

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

scientific article published on 18 January 2019

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis.

scientific article published on 20 October 2015

The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.

scientific article published in June 2009

The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations

scientific article

The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica.

scientific article

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

scientific article published on 28 September 2016

The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease

scientific article

The phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family.

scientific article published on January 2011

Transcriptome and secretome analysis of intra-mammalian life-stages of the emerging helminth pathogen, Calicophoron daubneyi reveals adaptation to a unique host environment

scientific article published on 20 October 2020

Triclabendazole-resistant Fasciola hepatica: beta-tubulin and response to in vitro treatment with triclabendazole.

scientific article published in March 2002

Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.

scientific article published on 15 July 2016

Worm secretory molecules are causing alarm

scientific article published on 09 June 2010

Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases.

scientific article

List of works by Mark W Robinson

A comparative proteomics analysis of the egg secretions of three major schistosome species

A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides

A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase.

A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis.

An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host.

Antimicrobial peptides: utility players in innate immunity.

Benzimidazole binding to Haemonchus contortus tubulin: a question of structure.

Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation

Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini.

Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.

Comparative analysis of the excretory–secretory proteome of the muscle larva of Trichinella pseudospiralis and Trichinella spiralis

Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules?

Development of the vitellaria of the liver fluke, Fasciola hepatica in the rat host

Extracellular Vesicle Biogenesis in Helminths: More than One Route to the Surface?

Extracellular vesicle-mediated communication in host-parasite interactions: insight from Fasciola hepatica.

Fasciola gigantica: Comparison of the tegumental ultrastructure in newly excysted metacercariae and in vitro penetrated juvenile flukes indicates intracellular sources of molecules with vaccinal and immunomodulatory potential

Fasciola hepatica expresses multiple alpha- and beta-tubulin isotypes.

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective.

Fasciola hepatica: the therapeutic potential of a worm secretome.

Helminth cysteine proteases inhibit TRIF-dependent activation of macrophages via degradation of TLR3.

Helminth defence molecules-immunomodulators designed by parasites!

Helminth pathogen cathepsin proteases: it's a family affair.

Immunomodulatory molecules of Fasciola hepatica: candidates for both vaccine and immunotherapeutic development

Infection by the helminth parasite Fasciola hepatica requires rapid regulation of metabolic, virulence, and invasive factors to adjust to its mammalian host.

MHJ_0125 is an M42 glutamyl aminopeptidase that moonlights as a multifunctional adhesin on the surface of Mycoplasma hyopneumoniae

Optimized conditions for the in vitro excystment of Calicophoron daubneyi metacercariae.

Paramphistomosis of Ruminants: An Emerging Parasitic Disease in Europe

Profiling excretory/secretory proteins of Trichinella spiralis muscle larvae by two-dimensional gel electrophoresis and mass spectrometry

Proteomic analysis of the excretory-secretory proteins of the Trichinella spiralis L1 larva, a nematode parasite of skeletal muscle.

Proteomics and phylogenetic analysis of the cathepsin L protease family of the helminth pathogen Fasciola hepatica: expansion of a repertoire of virulence-associated factors.

RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini.

Response to Morley: The Influence of Climate on Survival of Paramphistome Metacercariae

Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells.

Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B

Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse

Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.

Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis.

The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum: importance of active site metal ions in the binding of substrates and inhibitors.

The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations

The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica.

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

The importance of pH in regulating the function of the Fasciola hepatica cathepsin L1 cysteine protease

The phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family.

Transcriptome and secretome analysis of intra-mammalian life-stages of the emerging helminth pathogen, Calicophoron daubneyi reveals adaptation to a unique host environment

Triclabendazole-resistant Fasciola hepatica: beta-tubulin and response to in vitro treatment with triclabendazole.

Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.

Worm secretory molecules are causing alarm

Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases.