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List of works by Cormac G Gahan

A PrfA-regulated bile exclusion system (BilE) is a novel virulence factor in Listeria monocytogenes.

scientific article

A five-gene stress survival islet (SSI-1) that contributes to the growth of Listeria monocytogenes in suboptimal conditions

scientific article published on 01 September 2010

A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes.

scientific article

A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice.

scientific article published on 25 October 2012

A mutant of Listeria monocytogenes LO28 unable to induce an acid tolerance response displays diminished virulence in a murine model

scientific article published in December 1997

A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.

scientific article

A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions.

scientific article published on 19 January 2012

A novel promoter trap identifies Listeria monocytogenes promoters expressed at a low pH within the macrophage phagosome

scientific article published on 03 July 2007

A postgenomic appraisal of osmotolerance in Listeria monocytogenes

scientific article

Acid adaptation of Listeria monocytogenes can enhance survival in acidic foods and during milk fermentation.

scientific article

Acid stress responses in Listeria monocytogenes.

scientific article published on January 2008

Adaptive acid tolerance response in Listeria monocytogenes: isolation of an acid-tolerant mutant which demonstrates increased virulence

scientific article

AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes

article

Altered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.

scientific article

An in vitro cell-culture model demonstrates internalin- and hemolysin-independent translocation of Listeria monocytogenes across M cells

scientific article published on 16 October 2006

Analysis of the Impact of Rosuvastatin on Bacterial Mevalonate Production Using a UPLC-Mass Spectrometry Approach

scientific article published on 10 March 2016

Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection

scientific article published on 02 September 2008

Analysis of the role of OpuC, an osmolyte transport system, in salt tolerance and virulence potential of Listeria monocytogenes

scientific article

Analysis of the role of the Listeria monocytogenes F0F1 -AtPase operon in the acid tolerance response

scientific article published on 01 September 2000

Bacterial bile salt hydrolase in host metabolism: Potential for influencing gastrointestinal microbe-host crosstalk

scientific article

Bacterial systems for gene delivery to systemic tumors

scientific article published on January 2014

Bacteriophage Can Prevent Encrustation and Blockage of Urinary Catheters by Proteus mirabilis.

scientific article published on 28 December 2015

Betaine and carnitine uptake systems in Listeria monocytogenes affect growth and survival in foods and during infection.

scientific article published in January 2003

Bile Acid Modifications at the Microbe-Host Interface: Potential for Nutraceutical and Pharmaceutical Interventions in Host Health

scientific article published on 11 January 2016

Bile salt hydrolase activity in probiotics.

scientific article

Bile stress response in Listeria monocytogenes LO28: adaptation, cross-protection, and identification of genetic loci involved in bile resistance

scientific article

CesRK, a Two-Component Signal Transduction System in Listeria monocytogenes , Responds to the Presence of Cell Wall-Acting Antibiotics and Affects β-Lactam Resistance ⬇️

scientific article published on November 1, 2003

Characterization of the groESL operon in Listeria monocytogenes: utilization of two reporter systems (gfp and hly) for evaluating in vivo expression.

scientific article

Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria.

scientific article

Contribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes.

scientific article

Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn's Disease and Ulcerative Colitis

scientific article published in January 2018

Development of a Click Beetle Luciferase Reporter System for Enhanced Bioluminescence Imaging of Listeria monocytogenes: Analysis in Cell Culture and Murine Infection Models

scientific article published on 26 September 2017

Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector

scientific article

Directed evolution and targeted mutagenesis to murinize Listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model

scientific article

Disease-Associated Changes in Bile Acid Profiles and Links to Altered Gut Microbiota.

scientific article

Disruption of putative regulatory loci in Listeria monocytogenes demonstrates a significant role for Fur and PerR in virulence

scientific article published on February 2004

Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance

scientific article

Draft Genome Sequences of Listeria monocytogenes Serotype 4b Strains 944 and 2993 and Serotype 1/2c Strains 198 and 2932.

scientific article published on 2 June 2016

E. coli O104:H4: social media and the characterization of an emerging pathogen.

scientific article published in July 2011

Editorial [Hot Topic: Bacterial Vectors for Gene & Cell Therapy]

scientific article published on 01 February 2010

Enhancing bile tolerance improves survival and persistence of Bifidobacterium and Lactococcus in the murine gastrointestinal tract

scientific article published on 09 October 2008

Evidence for plasmid-mediated salt tolerance in the human gut microbiome and potential mechanisms.

scientific article published on 4 February 2016

Expression of two Listeria monocytogenes antigens (P60 and LLO) in Lactococcus lactis and examination for use as live vaccine vectors

scientific article published on 20 May 2010

Factors affecting survival of Listeria monocytogenes and Listeria innocua in soil samples

scientific article published on 25 May 2011

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome.

scholarly article

Gastrointestinal phase of Listeria monocytogenes infection.

scientific article

Genomic Characterization of Listeria monocytogenes Isolates Associated with Clinical Listeriosis and the Food Production Environment in Ireland.

scientific article

Genomic and Ecogenomic Characterization of Proteus mirabilis Bacteriophages

scientific article published on 06 August 2019

Gut microbiota-mediated bile acid transformations alter the cellular response to multidrug resistant transporter substrates in vitro: focus on P-glycoprotein

scientific article published on 16 November 2018

High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting

scientific article (publication date: 2012)

HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe.

scientific article

Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection

scientific article

Identification and disruption of BetL, a secondary glycine betaine transport system linked to the salt tolerance of Listeria monocytogenes LO28.

scientific article

Identification and disruption of btlA, a locus involved in bile tolerance and general stress resistance in Listeria monocytogenes.

scientific article published in January 2003

Identification and disruption of the proBA locus in Listeria monocytogenes: role of proline biosynthesis in salt tolerance and murine infection

scientific article

Impact of Gut Microbiota-Mediated Bile Acid Metabolism on the Solubilization Capacity of Bile Salt Micelles and Drug Solubility.

scientific article

Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro.

scientific article published on 9 March 2007

Influence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.

scientific article

Innate resistance to Listeria monocytogenes in tumor-bearing mice

scientific article published on 01 December 1997

Investigation of the mechanisms by which Listeria monocytogenes grows in porcine gallbladder bile.

scientific article

Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes

scientific article published on 20 December 2011

Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe

scientific article published on 08 February 2019

Lactococcus lactis as a cell factory for delivery of therapeutic proteins.

scientific article published on February 2010

Lactococcus lactis subsp. lactis as a natural anti-listerial agent in the mushroom industry

scientific article published on 28 January 2019

Lactococcus lactis-based vaccines: Current status and future perspectives ⬇️

scientific article published on January 1, 2011

Listeria monocytogenes PerR mutants display a small-colony phenotype, increased sensitivity to hydrogen peroxide, and significantly reduced murine virulence

scientific article

Listeria monocytogenes as a vector for anti-cancer therapies

scientific article published on February 2010

Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms

scientific article published on 23 February 2016

Listeria monocytogenes: survival and adaptation in the gastrointestinal tract.

scientific article published on 05 February 2014

M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis.

scientific article published on 10 December 2007

Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection

scientific article published on 11 February 2019

Microbiome-Mediated Bile Acid Modification: Role in Intestinal Drug Absorption and Metabolism.

scientific article published on 13 April 2018

Molecular pathogenesis of Listeria monocytogenes in the alternative model host Galleria mellonella.

scientific article published on 5 August 2010

Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity.

scientific article

Mutations in the listerial proB gene leading to proline overproduction: effects on salt tolerance and murine infection

scientific article

Nisin inducible production of listeriolysin O in Lactococcus lactis NZ9000

scientific article published on 29 July 2008

Non-dystrophic 129 REJ mice are susceptible to i.p. infection with Listeria monocytogenes despite an ability to recruit inflammatory neutrophils to the peritoneal cavity

scientific article published on 01 May 1995

Novel luciferase reporter system for in vitro and organ-specific monitoring of differential gene expression in Listeria monocytogenes

scientific article

Occurrence, Persistence, and Virulence Potential of Listeria ivanovii in Foods and Food Processing Environments in the Republic of Ireland.

scientific article published on 12 October 2015

Presence of GadD1 glutamate decarboxylase in selected Listeria monocytogenes strains is associated with an ability to grow at low pH.

scientific article

Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation

scientific article

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

scientific article

Role for HtrA in stress induction and virulence potential in Listeria monocytogenes.

scientific article

Shedding light on betL*: pPL2-lux mediated real-time analysis of betL* expression in Listeria monocytogenes.

scientific article published on April 2016

Short bowel syndrome (SBS)-associated alterations within the gut-liver axis evolve early and persist long-term in the piglet model of short bowel syndrome

scientific article

Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection

scientific article published on 18 January 2019

Signature tagged mutagenesis in the functional genetic analysis of gastrointestinal pathogens.

scientific article

Specific osmolyte transporters mediate bile tolerance in Listeria monocytogenes

scientific article published on 08 September 2009

Structure-activity relationships of furanones, dihydropyrrolones and thiophenones as potential quorum sensing inhibitors

scientific article published on 23 October 2020

The CtsR regulator of Listeria monocytogenes contains a variant glycine repeat region that affects piezotolerance, stress resistance, motility and virulence.

scientific article published in September 2003

The Impact of the Gut Microbiota on Drug Metabolism and Clinical Outcome

scientific article

The bacterial lux reporter system: applications in bacterial localisation studies

scientific article published on February 2012

The glutamate decarboxylase acid resistance mechanism affects survival of Listeria monocytogenes LO28 in modified atmosphere-packaged foods

scientific article published on 01 December 2007

The gut microbiota and the metabolic health of the host

scientific article published on March 2014

The influence of rosuvastatin on the gastrointestinal microbiota and host gene expression profiles.

scientific article

The interaction between Listeria monocytogenes and the host gastrointestinal tract.

scientific article published on 18 June 2009

The interaction between bacteria and bile.

scientific article

The interplay between classical and alternative isoprenoid biosynthesis controls gammadelta T cell bioactivity of Listeria monocytogenes.

scientific article published in March 2004

The relationship between acid stress responses and virulence in Salmonella typhimurium and Listeria monocytogenes

scientific article

The use of Listeria monocytogenes as a DNA delivery vector for cancer gene therapy ⬇️

scientific article published on March 7, 2010

Tools for functional postgenomic analysis of listeria monocytogenes.

scientific article published on 25 April 2008

Two-Dimensional Polyacrylamide Gel Electrophoresis Analysis of the Acid Tolerance Response in Listeria monocytogenes LO28

scientific article

Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors.

scientific article published on 6 November 2013

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk

scientific article

Understanding the mechanisms by which probiotics inhibit gastrointestinal pathogens.

scientific article published on January 2009

Vaccination of mice with attenuated mutants of Listeria monocytogenes: requirement for induction of macrophage la expression.

scientific article published in June 1995

Vaccination studies: detection of a Listeria monocytogenes-specific T cell immune response using the ELISPOT technique

scientific article published in January 2014

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