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List of works by Charles R Guttmann

3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis

scientific article

A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis.

scientific article

A Sensitive and Automatic White Matter Fiber Tracts Model for Longitudinal Analysis of Diffusion Tensor Images in Multiple Sclerosis.

scientific article

A highly immunogenic trivalent T cell receptor peptide vaccine for multiple sclerosis

scientific article published on 01 October 2005

A longitudinal study of callosal atrophy and interhemispheric dysfunction in relapsing-remitting multiple sclerosis.

scientific article published in January 2001

A method for the analysis of the geometrical relationship between white matter pathology and the vascular architecture of the brain.

scientific article published in August 2004

A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy

scientific article published on 01 December 1996

A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis

scientific article

A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis.

scientific article

A rhesus monkey reference label atlas for template driven segmentation

scientific article published on 05 May 2008

A simple noninvasive stereotactic device for routine MR head examinations.

scientific article published in July 1996

Abstracts from the ASENT 2008 Annual Meeting March 6–8, 2008.

scientific article

Abstracts from the ASENT 2010 annual meeting March 4–6, 2010.

scientific article published in July 2010

Accrual of MRI white matter abnormalities in elderly with normal and impaired mobility

scientific article published in May 2005

An MRI study of age-related white and gray matter volume changes in the rhesus monkey

scientific article published on 24 April 2007

An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2.

scientific article

Application of spherical harmonics derived space rotation invariant indices to the analysis of multiple sclerosis lesions' geometry by MRI.

scientific article published in July 2004

Aquaporin 4 distribution in the brain and its relevance for the radiological appearance of neuromyelitis optica spectrum disease

scientific article published on 11 April 2019

Atlas-derived perfusion correlates of white matter hyperintensities in patients with reduced cardiac output

scientific article

Automated segmentation of multiple sclerosis lesion subtypes with multichannel MRI.

scientific article published on 22 June 2006

Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people.

scientific article published on November 2011

Boutiques: a flexible framework to integrate command-line applications in computing platforms.

scientific article published in May 2018

Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis.

scientific article

Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia.

scientific article published on 28 February 2015

Brain regional lesion burden and impaired mobility in the elderly

scientific article

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

scientific article published in September 2008

Can MRI reveal phenotypes of multiple sclerosis?

scientific article published on 10 March 2006

Cardiovascular risk factors and small vessel disease of the brain: Blood pressure, white matter lesions, and functional decline in older persons

scientific article

Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance.

scientific article published on 11 July 2016

Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis

scientific article published on 01 August 2000

Changes in serum levels of ICAM and TNF-R correlate with disease activity in multiple sclerosis.

scientific article

Changes to the septo-fornical area might play a role in the pathogenesis of anxiety in multiple sclerosis

scientific article published in May 2017

Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis

scientific article published on 6 March 2017

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus

scientific article published on 30 October 2013

Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis.

scientific article

Cognitive profile and brain morphological changes in obstructive sleep apnea

scientific article

Computation of transmitted and received B1 fields in magnetic resonance imaging.

scientific article

Corrigendum: Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System

scientific article published on 15 September 2020

Daclizumab use in patients with pediatric multiple sclerosis

scientific article published on 01 January 2012

Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis

scientific article published on January 2009

Demographic and biological influences on cognitive reserve

scientific article published on 31 March 2009

Diagnostic value of 3DFLAIR in clinical practice for the detection of infratentorial lesions in multiple sclerosis in regard to dual echo T2 sequences.

scientific article published on 15 March 2018

Diffusion Tensor and Functional MRI Fusion with Anatomical MRI for Image-Guided Neurosurgery

article

Diffusion Tensor–MRI Evidence for Extra-Axonal Neuronal Degeneration in Caudate and Thalamic Nuclei of Patients with Multiple Sclerosis ⬇️

scientific article published on March 1, 2012

Disconnection mechanism and regional cortical atrophy contribute to impaired processing of facial expressions and theory of mind in multiple sclerosis: a structural MRI study

scientific article

Disease modeling in multiple sclerosis: assessment and quantification of sources of variability in brain parenchymal fraction measurements.

scientific article published in April 2010

Dual-Sensitivity Multiple Sclerosis Lesion and CSF Segmentation for Multichannel 3T Brain MRI.

scientific article published on 13 December 2017

Early Fiber Number Ratio Is a Surrogate of Corticospinal Tract Integrity and Predicts Motor Recovery After Stroke.

scientific article published on 15 March 2016

Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)

scientific article published on 14 October 2019

Estimating Time to Event From Longitudinal Categorical Data: An Analysis of Multiple Sclerosis Progression

scientific article

Evaluating the Association between Enlarged Perivascular Spaces and Disease Worsening in Multiple Sclerosis

scientific article published on 11 December 2017

Evidence of axonal damage in cerebellar peduncles without T2-lesions in multiple sclerosis

scientific article published on 17 September 2018

Exploration of machine learning techniques in predicting multiple sclerosis disease course

scientific article

Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients

scientific article published on 26 February 2016

Functional MRI of auditory verbal working memory: long-term reproducibility analysis.

scientific article published on March 2004

Functional MRI with variable echo time acquisition.

scientific article published in December 2003

Functional asymmetry in human primary auditory cortex: identified from longitudinal fMRI study

scientific article

HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study

article

Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models

scientific article

Has your patient's multiple sclerosis lesion burden or brain atrophy actually changed?

scientific article published on 01 August 2004

Head circumference as a useful surrogate for intracranial volume in older adults

scientific article published in January 2016

Hippocampal microstructural damage correlates with memory impairment in clinically isolated syndrome suggestive of multiple sclerosis

scientific article published on 25 October 2016

History of fatigue in multiple sclerosis is associated with grey matter atrophy

scientific article published on 14 October 2019

Human gray matter: feasibility of single-slab 3D double inversion-recovery high-spatial-resolution MR imaging.

scientific article published on 19 October 2006

INtensive versus standard ambulatory blood pressure lowering to prevent functional DeclINe in the ElderlY (INFINITY).

scientific article published on 5 January 2013

Identification and Characterization of Leptomeningeal Metastases Using SPINE, A Web-Based Collaborative Platform

scientific article published on 17 December 2020

Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging.

scientific article

Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data

scientific article published on 06 April 2021

Image processing: global and regional changes with age.

scientific article

Image registration framework for large-scale longitudinal MRI data sets: strategy and validation.

scientific article

Impaired cerebrovascular hemodynamics are associated with cerebral white matter damage.

scientific article published on 16 October 2013

In vivo characterization of cytotoxic intracellular edema by multicomponent analysis of transverse magnetization decay curves.

scientific article published in May 1995

Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study.

scientific article published on 9 May 2009

Incorporating domain knowledge into the fuzzy connectedness framework: application to brain lesion volume estimation in multiple sclerosis

scientific article published in December 2007

Interferon beta 1b following natalizumab discontinuation: one year, randomized, prospective, pilot trial.

scientific article

Intraoperative dynamic MRI: localization of sites of brain tumor recurrence after high-dose radiotherapy.

scientific article published on September 1998

Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability.

scientific article published in May 2005

Localization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults

scientific article published on 21 April 2009

Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials

scientific article published in May 2010

Long-term reproducibility analysis of fMRI using hand motor task.

scientific article published in January 2005

Longitudinal MRI in multiple sclerosis: correlation between disability and lesion burden

scientific article published on 01 November 1994

Longitudinal diffusion changes following postoperative delirium in older people without dementia

scientific article

Longitudinal microstructural changes of cerebral white matter and their association with mobility performance in older persons.

scientific article published on 19 March 2018

MR imaging intensity modeling of damage and repair in multiple sclerosis: relationship of short-term lesion recovery to progression and disability

scientific article published on 01 November 2007

MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals.

scientific article published in February 2003

MRI guided interstitial laser therapy in a rat malignant glioma model.

scientific article published on January 1993

MRI in multiple sclerosis: current status and future prospects

scientific article

MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information

scientific article published on 29 December 2006

MRI time series modeling of MS lesion development.

scientific article published on 27 June 2006

Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study

scientific article published on 28 December 2011

Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy

scientific article published in July 2004

Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia.

scientific article published in January 2008

Manual and automated tissue segmentation confirm the impact of thalamus atrophy on cognition in multiple sclerosis: A multicenter study

scientific article published on 25 December 2020

Medulla Oblongata Volume: A Biomarker of Spinal Cord Damage and Disability in Multiple Sclerosis: Fig 1

scientific article published on 12 June 2008

Microstructural changes in the striatum and their impact on motor and neuropsychological performance in patients with multiple sclerosis

scientific article

Mobility decline in the elderly relates to lesion accrual in the splenium of the corpus callosum

scientific article published on 20 April 2011

Mobility impairment is associated with reduced microstructural integrity of the inferior and superior cerebellar peduncles in elderly with no clinical signs of cerebellar dysfunction

scientific article published on March 2013

Multi-component apparent diffusion coefficients in human brain: relationship to spin-lattice relaxation.

scientific article

Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis

scientific article published on 29 May 2008

Multiple sclerosis lesion formation and early evolution revisited: A weekly high-resolution magnetic resonance imaging study

scientific article published on 11 September 2015

Multiple sclerosis medical image analysis and information management.

scientific article

Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome.

scientific article published on 11 April 2013

Multiresolution data acquisition and detection in functional MRI.

scientific article

Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI.

scientific article published on 26 February 2016

Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study.

scientific article

New OFSEP recommendations for MRI assessment of multiple sclerosis patients: Special consideration for gadolinium deposition and frequent acquisitions

scientific article published on 31 January 2020

No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50

scientific article

Objective Evaluation of Multiple Sclerosis Lesion Segmentation using a Data Management and Processing Infrastructure

scientific article published in Scientific Reports

Older people with impaired mobility have specific loci of periventricular abnormality on MRI

article

One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis

scientific article published on 22 March 2011

Perivascular Unit: This Must Be the Place. The Anatomical Crossroad Between the Immune, Vascular and Nervous System

scientific article published on 16 April 2020

Posterior lobules of the cerebellum and information processing speed at various stages of multiple sclerosis

scientific article published on 27 October 2016

Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence

scientific article published on 01 September 2019

Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale.

scientific article

Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis. Gadolinium MRI Meta-analysis Group.

scientific article

Present and future applications of lasers in neurosurgery.

scientific article published on December 1993

Processing speed in normal aging: effects of white matter hyperintensities and hippocampal volume loss

scientific article published on 29 July 2013

Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study

scientific article

Quantitative analysis of MRI signal abnormalities of brain white matter with high reproducibility and accuracy.

scientific article published in February 2002

Quantitative follow-up of patients with multiple sclerosis using MRI: technical aspects.

scientific article published in April 1999

Radial diffusivity in the cerebellar peduncles correlates with clinical severity in Friedreich ataxia.

scientific article published on 3 May 2013

Rapid buildup of brain white matter hyperintensities over 4 years linked to ambulatory blood pressure, mobility, cognition, and depression in old persons.

scientific article published on 13 June 2013

Rate of brain atrophy in benign vs early multiple sclerosis.

scientific article

Real-time adaptive functional MRI

scientific article published on 01 November 1999

Reduced accuracy of MRI deep grey matter segmentation in multiple sclerosis: an evaluation of four automated methods against manual reference segmentations in a multi-center cohort

scientific article published on 03 July 2020

Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies

scientific article

Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data

scientific article

Relationships among clinic, home, and ambulatory blood pressures with small vessel disease of the brain and functional status in older people with hypertension

scientific article published on 11 August 2018

Reliability and validity of MRI-based automated volumetry software relative to auto-assisted manual measurement of subcortical structures in HIV-infected patients from a multisite study

scientific article

Reply: Neural substrates of vulnerability to post-surgical delirium with prospective diagnosis

scientific article published on 24 June 2016

Response to Letters Regarding Article, “Average Daily Blood Pressure, Not Office Blood Pressure, Is Associated With Progression of Cerebrovascular Disease and Cognitive Decline in Older People”

Selection of voxel size and slice orientation for fMRI in the presence of susceptibility field gradients: application to imaging of the amygdala.

scientific article

Serial Neuropsychological Assessment and Magnetic Resonance Imaging Analysis in Multiple Sclerosis ⬇️

scientific article published on August 1, 1997

Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters

scientific article published on 27 June 2006

Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage

scientific article published on 01 May 2000

Simplified MRI prediction of clinically definite multiple sclerosis: a stepping stone towards treatment criteria?

scientific article published on 22 January 2008

Smoking and disease progression in multiple sclerosis

scientific article published on July 2009

Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging.

scientific article published on 21 February 2008

Spectroscopic imaging of the knee with line scan CPMG sequences.

scientific article published on March 1995

Spin-Echo planar spectroscopic imaging for fast lipid characterization in bone marrow

scientific article published on 01 October 1999

Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study

scientific article published on April 2009

State of the Art and Promise of Structural Neuroimaging in Postoperative Delirium and Postoperative Cognitive Decline

scientific article

Stroke Location Is an Independent Predictor of Cognitive Outcome

scientific article published on 19 November 2015

Subtraction MR images in a multiple sclerosis multicenter clinical trial setting

scientific article

Temporal association of sNfL and gad-enhancing lesions in multiple sclerosis

scientific article published on 25 May 2020

Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease.

scientific article published on 26 December 2008

Thalamic atrophy and cognition in multiple sclerosis

scientific article published on 01 September 2007

Thalamic fractional anisotropy predicts accrual of cerebral white matter damage in older subjects with small-vessel disease

scientific article

The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative.

scientific article published on 11 November 2016

The effect of alcohol and red wine consumption on clinical and MRI outcomes in multiple sclerosis

scientific article published on 27 June 2017

The evolution of multiple sclerosis lesions on serial MR

scientific article published on 01 August 1995

The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis

scientific article

The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis

scientific article published on 29 March 2011

The relationships among MRI-defined spinal cord involvement, brain involvement, and disability in multiple sclerosis

scientific article

Three-dimensional analysis of the geometry of individual multiple sclerosis lesions: detection of shape changes over time using spherical harmonics

scientific article published in September 2003

Time-series analysis of MRI intensity patterns in multiple sclerosis.

scientific article published in October 2003

Time-series modeling of multiple sclerosis disease activity: a promising window on disease progression and repair potential?

scientific article

Treatment satisfaction, adherence and behavioral assessment in patients de-escalating from natalizumab to interferon β

scientific article published on 28 February 2014

Triexponential decomposition of 1H spin-lattice relaxation decay curves of paramagnetically doped red cell suspensions at 7 T.

scientific article published on February 1996

Unbiased treatment effect estimates by modeling the disease process of multiple sclerosis.

scientific article

Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis.

scientific article

Weekly multimodal MRI follow-up of two multiple sclerosis active lesions presenting a transient decrease in ADC.

scientific article

White matter changes in patients with friedreich ataxia after treatment with erythropoietin

scientific article published on 09 September 2013

White matter changes with normal aging.

scientific article published in April 1998

White matter hyperintensities predict functional decline in voiding, mobility, and cognition in older adults

scientific article published on 26 January 2010

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