List of works - John A Kirby

A role for cytokine measurement in therapeutic monitoring of immunosuppressive drugs following lung transplantation

scientific article published on 01 February 2005

Adhesion of lymphocytes to bladder cancer cells: the role of the alpha(E)beta(7) integrin

scientific article published on 9 August 2002

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

scientific article published on 01 November 2018

An apparent paradox: chemokine receptor agonists can be used for anti-inflammatory therapy.

scientific article published on 26 September 2006

Antibody-mediated allograft rejection: the emerging role of endothelial cell signalling and transcription factors.

scientific article published on 19 July 2011

Antigen presentation by endothelium: heparin reduces the immunogenicity of interferon-gamma-treated endothelial cells

scientific article published on 01 September 1997

Apoptosis as a mechanism for cell surface expression of the autoantigen pyruvate dehydrogenase complex.

scientific article published on June 2004

Assessment of non-heart-beating donor (NHBD) kidneys for viability on machine perfusion.

scientific article published in November 2000

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis

scientific article published on 29 October 2015

B lymphocytes acquire and present intracellular antigens that have relocated to the surface of apoptotic target cells

scientific article published on 01 June 2011

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

scientific article published on 01 April 2007

Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4+ T cell activation in vitro.

scientific article published on April 1999

Brain stem auditory evoked response for confirmation of brain death in the rat.

scientific article published in September 2008

Breakdown of tolerance to pyruvate dehydrogenase complex in experimental autoimmune cholangitis: a mouse model of primary biliary cirrhosis

scientific article published on 01 July 1999

Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12 ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2018

Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12.

scientific article

CCL2 nitration is a negative regulator of chemokine-mediated inflammation.

scientific article published on 14 March 2017

Cancer stem cells and side population cells in breast cancer and metastasis.

scientific article

Celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinoma.

scientific article published on 15 January 2008

Characterization by Acid α-Naphthyl Acetate Esterase Staining of the Spinal Cord Cellular Infiltrate in the Acute and Relapse Phases of Chronic Relapsing Experimental Allergic Encephalomyelitis

scientific article published on January 1, 1983

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation

scientific article published on 5 March 2012

Chemokines and breast cancer: a gateway to revolutionary targeted cancer treatments?

scientific article

Chronic allograft nephropathy: intraepithelial signals generated by transforming growth factor-beta and bone morphogenetic protein-7

scientific article published on 01 June 2006

Chronic relapsing experimental allergic encephalomyelitis. The presence in the cerebrospinal fluid of factors chemotactic for monocytes.

scientific article

Chronic relapsing experimental allergic encephalomyelitis: cerebrospinal fluid cytology and a comparison with meningeal and spinal cord pathology.

scientific article

Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4.

scientific article published on 12 July 2016

Comment on "CXCL9 Causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation".

scientific article

Comparison of proteolytic enzymes and glutathione S-transferase levels in non-heart-beating donors' (NHBD) kidney perfusates

scientific article published on 01 November 2000

Contribution of Toll-Like Receptor Activation to Lung Damage After Donor Brain Death ⬇️

scientific article published on October 15, 2010

Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse.

scientific article

Cyclooxygenase-2 inhibition: a potential mechanism for increasing the efficacy of bacillus calmette-guerin immunotherapy for bladder cancer.

scientific article published in July 2005

Development of a flow cytometric assay to quantify lymphocyte adhesion to cytokine-stimulated human endothelial and biliary epithelial cells

scientific article published on 01 May 1996

Distribution of lymphocytes of the alpha(E)beta(7) phenotype and E-cadherin in normal human urothelium and bladder carcinomas

scientific article published on 01 December 2001

Donor intravascular monocyte trafficking: a potential therapeutic target for primary graft dysfunction following lung transplantation?

scientific article published on 31 January 2018

Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

scientific article published on 9 November 2016

Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation.

scientific article

Epithelial to mesenchymal transition in primary sclerosing cholangitis

scientific article published on 01 September 2008

Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

scientific article published on 03 December 2007

Epithelial-to-mesenchymal transition: what is the impact on breast cancer stem cells and drug resistance

scientific article published on 15 September 2013

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

scientific article published on 9 May 2014

Evaluation of dendritic cell immunogenicity after activation and chemical fixation: a mixed lymphocyte reaction model

scientific article

Examination of the function of RANTES, MIP-1alpha, and MIP-1beta following interaction with heparin-like glycosaminoglycans

scientific article published on 01 April 2000

Expression of chemokine receptors CXCR1 and CXCR2 during cardiopulmonary bypass

scientific article published on 01 December 2001

Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism ⬇️

scientific article published on January 2, 2012

Functional assessment of non-heart-beating donor lungs: prediction of post-transplant function

scientific article published on 01 July 2001

Immunogenicity of biliary epithelial cells: study of the expression of B7 molecules

scientific article published on 01 May 1995

Immunogenicity of biliary epithelium: investigation of antigen presentation to CD4+ T cells.

scientific article published on September 1996

Immunogenicity of biliary epithelium: study of the adhesive interaction with lymphocytes

scientific article published on 01 March 1997

Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression.

scientific article published in April 2003

In situ lymphoproliferation in renal transplant biopsies

scientific article published on 01 October 1995

In vitro and in vivo evaluation of intrinsic immunogenicity of reporter and insulin gene therapy plasmids.

scientific article published in August 2007

Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?

scientific article published on March 2007

Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β.

scientific article

Limiting dilution analysis: quantification of IL-2 producing allospecific lymphocytes after renal and cardiac transplantation

scientific article published on 01 December 1994

Lung transplantation: the Yin and Yang of mesenchymal stem cells.

scientific article

Metal-on-metal hips: cobalt can induce an endotoxin-like response

scientific article published on 17 October 2012

Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo

scientific article published on 28 August 2007

Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis

scientific article

Non-heart-beating kidney donors

scientific article published on 01 June 2000

Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis.

scientific article published in December 2002

Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients.

scientific article published on 21 June 2005

Plasma TGF-beta1 as a risk factor for gingival overgrowth.

scientific article published in October 2004

Polarisation of a T-helper cell immune response by activation of dendritic cells with CpG-containing oligonucleotides: a potential therapeutic regime for bladder cancer immunotherapy.

scientific article published on December 2003

Post-transplant immunosuppression: regulation of the efflux of allospecific effector T cells from lymphoid tissues

scientific article

Post-transplant renal tubulitis: the recruitment, differentiation and persistence of intra-epithelial T cells.

scientific article

Potential role of indoleamine 2,3-dioxygenase in primary biliary cirrhosis

scientific article published on 28 August 2017

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

scientific article published on 13 July 2018

Randomized clinical trial of omega-3 fatty acid-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing oesophagogastric cancer surgery.

scientific article published on 11 January 2012

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease

scientific article published on 24 September 2021

Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational Nitration

scientific article published on 3 August 2017

Regulation of T-cell apoptosis: a mixed lymphocyte reaction model

scientific article published on 01 July 2000

Renal allograft rejection--in situ demonstration of cytotoxic intratubular cells.

scientific article published on May 1996

Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells ⬇️

scientific article published on May 23, 2012

Renal allograft rejection: examination of adhesion blockade by antilymphocyte antibody drugs

scientific article published on 01 January 1993

Renal allograft rejection: the contribution of chemokines to the adhesion and retention of alphaE(CD103)beta7 integrin-expressing intratubular T cells.

scientific article

Renal allograft rejection: the temporal relationship and predictive value of plasma TNF (alpha and beta), IFN-gamma and soluble ICAM-1

scientific article published on 01 January 1995

Renal epithelium: reversal of cytotoxic damage by addition of anti-thymocyte globulin ⬇️

scientific article published on December 1, 1991

Renal transplantation: examination of the regulation of chemokine binding during acute rejection.

scientific article published in March 2005

Role of 6-O-sulfated heparan sulfate in chronic renal fibrosis.

scientific article published on 30 May 2014

Role of the mucosal integrin alpha(E)(CD103)beta(7) in tissue-restricted cytotoxicity.

scientific article published on 2 April 2007

Secretory autoantibodies in primary biliary cirrhosis (PBC)

scientific article published on 01 December 2000

Selection of metastatic tumour phenotypes by host immune systems

scientific article published on 01 December 1999

Soluble E-cadherin: an early marker of severity in acute pancreatitis.

scientific article published on 27 April 2009

Stem cell therapy: a role for CXCR4 in homing bone marrow side population cells to areas of myocardial damage

scientific article published on 16 June 2010

T cell extravasation: demonstration of synergy between activation of CXCR3 and the T cell receptor.

scientific article published on 20 September 2009

T cell-mediated biliary epithelial-to-mesenchymal transition in liver allograft rejection.

scientific article

T-cell anergy: a consequence of interaction between T cells and allogeneic rat renal epithelial cells

scientific article published on 01 January 1994

Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation

scientific article published on 31 January 2016

The Role of Chemokine and Glycosaminoglycan Interaction in Chemokine-Mediated Migration In Vitro and In Vivo

scientific article published on 14 November 2015

The effect of cyclosporin A and tacrolimus on cultured human epithelial cells: the role of TGF-beta

scientific article published on 01 February 1999

The effect of cyclosporin on cell division and apoptosis in human oral keratinocytes.

scientific article published on August 2006

The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip.

scientific article published on September 2014

The immunology of primary biliary cirrhosis: the end of the beginning?

scientific article

The molecular mechanism of cell activation by cobalt ions. Comment on Ninomiya et al.: Metal ions activate vascular endothelial cells and increase lymphocyte chemotaxis and binding

scientific article published on 01 August 2013

The number of intraepithelial T cells decreases from ascending colon to rectum.

scientific article published in February 2003

The role of FOXP3 in the development and metastatic spread of breast cancer.

scientific article published on December 2012

The role of beta 1 integrins in adhesion of two breast carcinoma cell lines to a model endothelium.

scientific article

The role played by adhesion molecules during allograft rejection

scientific article published on 01 June 1994

Therapy with nonglycosaminoglycan-binding mutant CCL7: a novel strategy to limit allograft inflammation

scientific article published on 24 November 2009

Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.

scientific article published on 26 September 2016

Toll-like receptor (TLR) response tolerance: a key physiological "damage limitation" effect and an important potential opportunity for therapy.

scientific article published on January 2006

Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production

scientific article published on 11 October 2006

Transplant immunobiology: a crucial role for heparan sulfate glycosaminoglycans?

scientific article

Transplantation and inflammation: implications for the modification of chemokine function

scientific article

Tubulitis after renal transplantation: demonstration of an association between CD103+ T cells, transforming growth factor beta1 expression and rejection grade

scientific article

Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation

scientific article published on September 2010

Xenotransplantation: an examination of the adhesive interactions between human lymphocytes and porcine renal epithelial cells

scientific article published on 01 September 1994

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

scientific article published on May 2017

β-chemokine expression and distribution in paraffin-embedded transplant renal biopsy sections: analysis by scanning laser confocal microscopy ⬇️

scientific article published on August 1, 1998

List of works by John A Kirby

A role for cytokine measurement in therapeutic monitoring of immunosuppressive drugs following lung transplantation

Adhesion of lymphocytes to bladder cancer cells: the role of the alpha(E)beta(7) integrin

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

An apparent paradox: chemokine receptor agonists can be used for anti-inflammatory therapy.

Antibody-mediated allograft rejection: the emerging role of endothelial cell signalling and transcription factors.

Antigen presentation by endothelium: heparin reduces the immunogenicity of interferon-gamma-treated endothelial cells

Apoptosis as a mechanism for cell surface expression of the autoantigen pyruvate dehydrogenase complex.

Assessment of non-heart-beating donor (NHBD) kidneys for viability on machine perfusion.

Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis

B lymphocytes acquire and present intracellular antigens that have relocated to the surface of apoptotic target cells

Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis

Bladder cancer immunogenicity: expression of CD80 and CD86 is insufficient to allow primary CD4+ T cell activation in vitro.

Brain stem auditory evoked response for confirmation of brain death in the rat.

Breakdown of tolerance to pyruvate dehydrogenase complex in experimental autoimmune cholangitis: a mouse model of primary biliary cirrhosis

Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12 ⬇️

Breast cancer metastasis: demonstration that FOXP3 regulates CXCR4 expression and the response to CXCL12.

CCL2 nitration is a negative regulator of chemokine-mediated inflammation.

Cancer stem cells and side population cells in breast cancer and metastasis.

Celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinoma.

Characterization by Acid α-Naphthyl Acetate Esterase Staining of the Spinal Cord Cellular Infiltrate in the Acute and Relapse Phases of Chronic Relapsing Experimental Allergic Encephalomyelitis

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation

Chemokines and breast cancer: a gateway to revolutionary targeted cancer treatments?

Chronic allograft nephropathy: intraepithelial signals generated by transforming growth factor-beta and bone morphogenetic protein-7

Chronic relapsing experimental allergic encephalomyelitis. The presence in the cerebrospinal fluid of factors chemotactic for monocytes.

Chronic relapsing experimental allergic encephalomyelitis: cerebrospinal fluid cytology and a comparison with meningeal and spinal cord pathology.

Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4.

Comment on "CXCL9 Causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation".

Comparison of proteolytic enzymes and glutathione S-transferase levels in non-heart-beating donors' (NHBD) kidney perfusates

Contribution of Toll-Like Receptor Activation to Lung Damage After Donor Brain Death ⬇️

Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse.

Cyclooxygenase-2 inhibition: a potential mechanism for increasing the efficacy of bacillus calmette-guerin immunotherapy for bladder cancer.

Development of a flow cytometric assay to quantify lymphocyte adhesion to cytokine-stimulated human endothelial and biliary epithelial cells

Distribution of lymphocytes of the alpha(E)beta(7) phenotype and E-cadherin in normal human urothelium and bladder carcinomas

Donor intravascular monocyte trafficking: a potential therapeutic target for primary graft dysfunction following lung transplantation?

Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation.

Epithelial to mesenchymal transition in primary sclerosing cholangitis

Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

Epithelial-to-mesenchymal transition: what is the impact on breast cancer stem cells and drug resistance

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

Evaluation of dendritic cell immunogenicity after activation and chemical fixation: a mixed lymphocyte reaction model

Examination of the function of RANTES, MIP-1alpha, and MIP-1beta following interaction with heparin-like glycosaminoglycans

Expression of chemokine receptors CXCR1 and CXCR2 during cardiopulmonary bypass

Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism ⬇️

Functional assessment of non-heart-beating donor lungs: prediction of post-transplant function

Immunogenicity of biliary epithelial cells: study of the expression of B7 molecules

Immunogenicity of biliary epithelium: investigation of antigen presentation to CD4+ T cells.

Immunogenicity of biliary epithelium: study of the adhesive interaction with lymphocytes

Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression.

In situ lymphoproliferation in renal transplant biopsies

In vitro and in vivo evaluation of intrinsic immunogenicity of reporter and insulin gene therapy plasmids.

Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?

Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-β.

Limiting dilution analysis: quantification of IL-2 producing allospecific lymphocytes after renal and cardiac transplantation

Lung transplantation: the Yin and Yang of mesenchymal stem cells.

Metal-on-metal hips: cobalt can induce an endotoxin-like response

Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo

Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis

Non-heart-beating kidney donors

Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis.

Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients.

Plasma TGF-beta1 as a risk factor for gingival overgrowth.

Polarisation of a T-helper cell immune response by activation of dendritic cells with CpG-containing oligonucleotides: a potential therapeutic regime for bladder cancer immunotherapy.

Post-transplant immunosuppression: regulation of the efflux of allospecific effector T cells from lymphoid tissues

Post-transplant renal tubulitis: the recruitment, differentiation and persistence of intra-epithelial T cells.

Potential role of indoleamine 2,3-dioxygenase in primary biliary cirrhosis

Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score

Randomized clinical trial of omega-3 fatty acid-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing oesophagogastric cancer surgery.

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease

Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational Nitration

Regulation of T-cell apoptosis: a mixed lymphocyte reaction model

Renal allograft rejection--in situ demonstration of cytotoxic intratubular cells.

Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells ⬇️

Renal allograft rejection: examination of adhesion blockade by antilymphocyte antibody drugs

Renal allograft rejection: the contribution of chemokines to the adhesion and retention of alphaE(CD103)beta7 integrin-expressing intratubular T cells.

Renal allograft rejection: the temporal relationship and predictive value of plasma TNF (alpha and beta), IFN-gamma and soluble ICAM-1

Renal epithelium: reversal of cytotoxic damage by addition of anti-thymocyte globulin ⬇️

Renal transplantation: examination of the regulation of chemokine binding during acute rejection.

Role of 6-O-sulfated heparan sulfate in chronic renal fibrosis.