List of works by Hugo Seca

Data supporting the shedding of larger extracellular vesicles by multidrug resistant tumour cells.

scientific article

Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold

EBV interferes with the sensitivity of Burkitt lymphoma Akata cells to etoposide

scientific article published on January 2011

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone.

scientific article

MicroRNAs in Cancer Drug Resistance and Drug Sensitivity

Multidrug resistant tumour cells shed more microvesicle-like EVs and less exosomes than their drug-sensitive counterpart cells.

scientific article published on 17 December 2015

Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.

scientific article

Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis

scientific article published on 13 January 2016

Simultaneous targeting of P-gp and XIAP with siRNAs increases sensitivity of P-gp overexpressing CML cells to imatinib.

scientific article published on March 2011

Sulfated small molecules targeting eBV in Burkitt lymphoma: from in silico screening to the evidence of in vitro effect on viral episomal DNA.

scientific article

Targeting miR-21 induces autophagy and chemosensitivity of leukemia cells.

scientific article published on September 2013

The network of P-glycoprotein and microRNAs interactions

scientific article published on 17 October 2013

Treatment of Akata EBV-positive cells with doxorubicin causes more EBV reactivation than treatment with etoposide

scientific article published on 29 April 2011

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