List of works - Lynda Elghazi

Akt and PTEN: beta-cell mass and pancreas plasticity.

scientific article published on 21 June 2009

Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

scientific article

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. ⬇️

scientific article

Decreased IRS signaling impairs beta-cell cycle progression and survival in transgenic mice overexpressing S6K in beta-cells

scientific article published on 9 July 2010

Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life

scientific article published on 01 December 2006

Disruption of Tsc2 in pancreatic beta cells induces beta cell mass expansion and improved glucose tolerance in a TORC1-dependent manner.

scholarly article

Emerging role of protein kinase B/Akt signaling in pancreatic beta-cell mass and function.

scientific article

Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip.

scientific article published on 12 February 2012

Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.

scientific article

Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitors

scientific article published on 24 September 2014

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

scientific article (publication date: 2 March 2004)

Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum

scientific article published on January 2008

Importance of β-Catenin in glucose and energy homeostasis

scientific article

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

scientific article

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

scientific article published in February 2006

Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

scientific article published on 01 October 2007

Noninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eye

scientific article

Regulation of beta-cell mass and function by the Akt/protein kinase B signalling pathway

scientific article published on November 2007

Regulation of pancreas plasticity and malignant transformation by Akt signaling.

scientific article

Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation

scientific article

S6K1 controls pancreatic β cell size independently of intrauterine growth restriction

scientific article

mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice

scientific article published on 18 April 2022

mTORC1 signaling and regulation of pancreatic β-cell mass

scientific article

List of works by Lynda Elghazi

Akt and PTEN: beta-cell mass and pancreas plasticity.

Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. ⬇️

Decreased IRS signaling impairs beta-cell cycle progression and survival in transgenic mice overexpressing S6K in beta-cells

Differential effects of p27 in regulation of beta-cell mass during development, neonatal period, and adult life

Disruption of Tsc2 in pancreatic beta cells induces beta cell mass expansion and improved glucose tolerance in a TORC1-dependent manner.

Emerging role of protein kinase B/Akt signaling in pancreatic beta-cell mass and function.

Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip.

Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.

Exposure of mouse embryonic pancreas to metformin enhances the number of pancreatic progenitors

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum

Importance of β-Catenin in glucose and energy homeostasis

Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms

Noninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eye

Regulation of beta-cell mass and function by the Akt/protein kinase B signalling pathway

Regulation of pancreas plasticity and malignant transformation by Akt signaling.

Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation

S6K1 controls pancreatic β cell size independently of intrauterine growth restriction

mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice

mTORC1 signaling and regulation of pancreatic β-cell mass