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List of works by Ingrid G Winkler

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

scientific article

A rapid streptavidin-capture ELISA specific for the detection of antibodies to feline foamy virus

scientific article published in August 1997

Acute Myeloid Leukemia Chemo-Resistance Is Mediated by E-selectin Receptor CD162 in Bone Marrow Niches

scientific article published on 24 July 2020

Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1.

scientific article published on 30 October 2003

Antibody to human foamy virus not detected in individuals treated with blood products or in blood donors

scientific article published in January 2000

B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2

scientific article published on 28 August 2012

Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner

scientific article published on 06 October 2020

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

scientific article

CD169(+) macrophages mediate pathological formation of woven bone in skeletal lesions of prostate cancer

scientific article published on 27 April 2016

Cellular players of hematopoietic stem cell mobilization in the bone marrow niche.

scientific article

Construction of infectious feline foamy virus genomes: cat antisera do not cross-neutralize feline foamy virus chimera with serotype-specific Env sequences

scientific article published in January 2000

Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells

scientific article published on 01 February 2005

Detection and molecular characterisation of feline foamy virus serotypes in naturally infected cats

scientific article published in August 1998

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

scientific article published on 27 April 2020

Engraftment Outcomes after HPC Co-Culture with Mesenchymal Stromal Cells and Osteoblasts

scientific article published on 23 September 2013

Flow cytometry analysis of cell cycling and proliferation in mouse hematopoietic stem and progenitor cells.

scientific article published in January 2012

Flow cytometry measurement of bone marrow perfusion in the mouse and sorting of progenitors and stems cells according to position relative to blood flow in vivo

scientific article published on 01 January 2012

Fms-like tyrosine kinase 3 (Flt3) ligand depletes erythroid island macrophages and blocks medullar erythropoiesis in the mouse.

scientific article published in December 2015

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow

scientific article published on 21 July 2005

Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

scientific article published on 01 February 2007

Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells

scientific article published in February 2003

HIF prolyl hydroxylase inhibitor FG-4497 enhances mouse hematopoietic stem cell mobilization via VEGFR2/KDR

scientific article published on 01 February 2019

HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

scientific article published on 12 January 2015

Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow

scientific article

Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation.

scientific article published on 23 January 2012

Hierarchy of immature hematopoietic cells related to blood flow and niche

scientific article published on July 2011

Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML.

scientific article published on 29 April 2015

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

scientific article published on 08 February 2020

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes.

scientific article published on 4 March 2014

It takes nerves to recover from chemotherapy

scientific article published on 01 June 2013

Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation

scientific article published in 2021

Mechanisms of hematopoietic stem cell mobilization: when innate immunity assails the cells that make blood and bone

scientific article published on August 2006

Mobilisation strategies for normal and malignant cells.

scientific article published on October 2011

Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment

scientific article published on 01 May 2002

Mobilization of hematopoietic stem cells by depleting bone marrow macrophages

scientific article published on 01 January 2012

Mobilization of hematopoietic stem cells with highest self-renewal by G-CSF precedes clonogenic cell mobilization peak

scientific article published on 28 January 2016

Mobilization of hematopoietic stem cells: state of the art.

scientific article published on February 2008

Mobilization with granulocyte colony-stimulating factor blocks medullar erythropoiesis by depleting F4/80(+)VCAM1(+)CD169(+)ER-HR3(+)Ly6G(+) erythroid island macrophages in the mouse

scientific article published on 08 April 2014

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage-mediated inflammation in muscle.

scientific article published on 26 March 2015

Nichotherapy for stem cells: there goes the neighborhood

scientific article

Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization

scientific article published in 2021

Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation.

scientific article published on 14 December 2012

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

scientific article

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

scientific article published on 26 June 2018

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization

scientific article

Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells

scientific article published on 01 May 2019

The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization

scientific article published on 23 September 2010

Tissue engineered humanized bone supports human hematopoiesis in vivo

scientific article

Tissue inhibitor of metalloproteinase-3 (TIMP-3) regulates hematopoiesis and bone formation in vivo

scientific article

Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

scientific article published on 21 October 2012

[E-selectin, a key regulator of the division of hematopoietic stem cells and their resistance to chemotherapy].

scientific article published on 27 March 2013

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