List of works - Helmut Bergler

A conserved inter-domain communication mechanism regulates the ATPase activity of the AAA-protein Drg1

scientific article published on 17 March 2017

Crystallization and preliminary X-ray diffraction studies of the enoyl-ACP reductase from Escherichia coli

scientific article published on 01 October 1994

Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1.

scientific article

Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.

scientific article

Diazaborine treatment of Baker's yeast results in stabilization of aberrant mRNAs

scientific article published on 26 July 2001

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

scientific article

From Snapshots to Flipbook-Resolving the Dynamics of Ribosome Biogenesis with Chemical Probes

scientific article published on 23 April 2020

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression

scientific article published on 01 August 2018

Inhibiting eukaryotic ribosome biogenesis.

scientific article published on 10 June 2019

Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

scientific article published in 2022

Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity

scientific article published on 31 October 2016

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

scientific article published on 22 May 2019

Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1.

scientific article

Protein EnvM is the NADH-dependent enoyl-ACP reductase (FabI) of Escherichia coli.

scientific article

Ribosomal protein S3 interacts with the NF-κB inhibitor IκBα

scientific article

Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation

scientific article

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.

scientific article published on 5 September 2017

Sequences of the envM gene and of two mutated alleles in Escherichia coli

scientific article published on October 1, 1992

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation.

scientific article published on 2 February 2016

Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization.

scientific article

The cadherin switch in melanoma instigated by HGF is mediated through epithelial-mesenchymal transition regulators

scientific article published on 07 December 2010

The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery

scientific article

The drug diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1.

scientific article published on 26 December 2013

The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

scientific article

The novel pre-rRNA detection workflow “Riboprobing” allows simple identification of undescribed RNA species.

scientific article published in 2024

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

scientific article published on 09 August 2007

Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma

scientific article published on 19 May 2011

Viewing pre-60S maturation at a minute's timescale.

scientific article published on 27 December 2017

Yar1 protects the ribosomal protein Rps3 from aggregation.

scientific article

eIF3a is over-expressed in urinary bladder cancer and influences its phenotype independent of translation initiation

scientific article published on 29 July 2014

List of works by Helmut Bergler

A conserved inter-domain communication mechanism regulates the ATPase activity of the AAA-protein Drg1

Crystallization and preliminary X-ray diffraction studies of the enoyl-ACP reductase from Escherichia coli

Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1.

Diazaborine resistance in the yeast Saccharomyces cerevisiae reveals a link between YAP1 and the pleiotropic drug resistance genes PDR1 and PDR3.

Diazaborine treatment of Baker's yeast results in stabilization of aberrant mRNAs

Diazaborine treatment of yeast cells inhibits maturation of the 60S ribosomal subunit

From Snapshots to Flipbook-Resolving the Dynamics of Ribosome Biogenesis with Chemical Probes

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression

Inhibiting eukaryotic ribosome biogenesis.

Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1.

Protein EnvM is the NADH-dependent enoyl-ACP reductase (FabI) of Escherichia coli.

Ribosomal protein S3 interacts with the NF-κB inhibitor IκBα

Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation

Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.

Sequences of the envM gene and of two mutated alleles in Escherichia coli

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation.

Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization.

The cadherin switch in melanoma instigated by HGF is mediated through epithelial-mesenchymal transition regulators

The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery

The drug diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1.

The enoyl-[acyl-carrier-protein] reductase (FabI) of Escherichia coli, which catalyzes a key regulatory step in fatty acid biosynthesis, accepts NADH and NADPH as cofactors and is inhibited by palmitoyl-CoA.

The novel pre-rRNA detection workflow “Riboprobing” allows simple identification of undescribed RNA species.

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma

Viewing pre-60S maturation at a minute's timescale.

Yar1 protects the ribosomal protein Rps3 from aggregation.

eIF3a is over-expressed in urinary bladder cancer and influences its phenotype independent of translation initiation