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List of works by Natalie Cook

A first-in-human phase 1 and pharmacological study of TAS-119, a novel selective Aurora A kinase inhibitor in patients with advanced solid tumours

scientific article published on 06 October 2020

A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

scientific article published on 11 April 2012

A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy

scientific article published on 23 March 2011

A phase 2 study of vatalanib in metastatic melanoma patients

scientific article published on 25 August 2010

Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer

scientific article (publication date: 2013)

Assessing the role of the EGF receptor in the development and progression of pancreatic cancer

article

Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice

scientific article published on 09 December 2011

Challenge of the Unknown: How Can We Improve Clinical Outcomes in Cancer of Unknown Primary?

scientific article published on 18 June 2019

Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma: a meta-analysis of patient-level data

scientific article

Choice of Starting Dose for Biopharmaceuticals in First-in-Human Phase I Cancer Clinical Trials

scientific article

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

scientific article published on 7 November 2011

Cumulative Antibiotic Use Significantly Decreases Efficacy of Checkpoint Inhibitors in Patients with Advanced Cancer

scientific article published on 10 July 2019

Determinants of the recommended phase 2 dose of molecular targeted agents

scientific article published on 9 February 2017

Direct histological processing of EUS biopsies enables rapid molecular biomarker analysis for interventional pancreatic cancer trials

scientific article

Discovery and Evaluation of Protein Biomarkers as a Signature of Wellness in Late-Stage Cancer Patients in Early Phase Clinical Trials

scientific article published in 2021

Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial

scientific article

E-Mail Communication Practices and Preferences Among Patients and Providers in a Large Comprehensive Cancer Center

scientific article published on 28 June 2016

Early phase clinical trials to identify optimal dosing and safety

scientific article

Endothelin-1 and endothelin B receptor expression in pancreatic adenocarcinoma

scientific article published on 08 January 2015

Exome-Wide Association Study of Pancreatic Cancer Risk

scientific article published on 23 October 2017

FOLFIRINOX for advanced pancreatic cancer: the Princess Margaret Cancer Centre experience

scientific article published on 28 July 2016

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

scientific article published on 20 February 2012

Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo

scientific article

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

scientific article published on 30 March 2012

K‐Ras‐Driven Pancreatic Cancer Mouse Model for Anticancer Inhibitor Analyses

scientific article published on 01 January 2008

Molecular characterisation and liquid biomarkers in Carcinoma of Unknown Primary (CUP): taking the ‘U’ out of ‘CUP’

scientific article published on 23 December 2018

Novel Early Phase Clinical Trial Design in Oncology

Predictive in vivo animal models and translation to clinical trials

scientific article published on March 2012

Reply to K.K. Sahu et al

scientific article published on 07 February 2017

Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin.

scientific article published on 20 June 2018

Small cell carcinoma of the urinary bladder: a 15-year retrospective review of treatment and survival in the Anglian Cancer Network

scientific article published on 05 December 2008

Stromal biology and therapy in pancreatic cancer.

scientific article published on 21 October 2010

The International Core Literature Consensus (ICLC): an alternative curriculum for Oncologists

scientific article published on September 2011

The pancreas cancer microenvironment

scientific article

Trimodality therapy and definitive chemoradiotherapy for esophageal cancer: a single-center experience and review of the literature

scientific article published on 27 May 2014

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

scientific article published on 22 April 2019

nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer

scientific article published on 28 February 2012

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