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List of works by Chantal Autexier

A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT.

scientific article published on November 2005

A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation

scientific article

A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells

scientific article published on 7 September 2015

A platinum supramolecular square as an effective G-quadruplex binder and telomerase inhibitor

scientific article published on 11 July 2008

A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization

scientific article published on 27 February 2013

ALTered telomeres in response to telomere dysfunction ⬇️

scientific article published on November 15, 2011

An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization

scientific journal article

An intact putative mouse telomerase essential N-terminal domain is necessary for proper telomere maintenance

scientific article published on 20 January 2016

Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects ⬇️

scientific article published on May 8, 2013

Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit

scientific article published on February 2002

Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer

scientific article

Growth defects in mouse telomerase RNA-deficient cells expressing a template-mutated mouse telomerase RNA.

scientific article

Harnessing telomerase in cancer therapeutics

scientific article published on July 2007

Human telomerase catalyzes nucleolytic primer cleavage

scientific article published on 19 April 2004

Humanized telomeres and an attempt to express a functional human telomerase in yeast

scientific article published on 26 March 2004

Inactive C-terminal telomerase reverse transcriptase insertion splicing variants are dominant-negative inhibitors of telomerase

scientific article published on 9 January 2014

Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases

scientific article published on 17 February 2016

POT of gold: modeling dyskeratosis congenita in the mouse

scientific article published on July 2008

Pharmacological telomerase inhibition can sensitize drug-resistant and drug-sensitive cells to chemotherapeutic treatment

scientific article published on 6 June 2005

Platinum(II) Phenanthroimidazoles for Targeting Telomeric G‐Quadruplexes ⬇️

scientific article published on November 3, 2011

Platinum(II) phenanthroimidazole G-quadruplex ligand induces selective telomere shortening in A549 cancer cells

scientific article published on 24 December 2015

Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase

scientific article published on September 2005

Regulation of telomere length and homeostasis by telomerase enzyme processivity

scientific article

Targeting human telomerase in cancer therapy

scientific article

Telomerase Contributes to Fludarabine Resistance in Primary Human Leukemic Lymphocytes ⬇️

scientific article published on July 29, 2013

Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation.

scientific article published on 3 April 2005

Telomerase Regulation from Beginning to the End

scientific article

Telomerase and neuronal marker status of differentiated NT2 and SK-N-SH human neuronal cells and primary human neurons.

scientific article

Telomerase can act as a template- and RNA-independent terminal transferase

scientific article

Telomerase inhibition enhances the response to anticancer drug treatment in human breast cancer cells

scientific article published on July 2006

Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation

scientific article published on 7 November 2007

Telomerase, senescence and ageing

scientific article published on 14 December 2007

Telomere biology: Rationale for diagnostics and therapeutics in cancer

scientific article (publication date: 2015)

Telomeric function of mammalian telomerases at short telomeres

scientific article

Telomeric recombination induced by dysfunctional telomeres

scientific article

The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity

scientific article published on July 2003

The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner

scientific article published on 26 October 2015

The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein

scientific article

The structure and function of telomerase reverse transcriptase

scientific article

Zscan4 Inhibits Maintenance DNA Methylation to Facilitate Telomere Elongation in Mouse Embryonic Stem Cells

scientific article published on August 2017

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