List of works - Emma C Josefsson

-methyl-d-aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines

scientific article published in January 2018

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

scientific article published on 25 July 2014

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

scientific article published on 19 June 2020

A model for studying the hemostatic consumption or destruction of platelets

scientific article

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

scientific article published on 2 November 2017

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion

scientific article

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

scientific article

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

scientific article

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia

scientific article

Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage

scientific article

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

scientific article published on 27 September 2009

Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia

scientific article

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

scientific article

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

scientific article published on 21 May 2018

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

scientific article

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.

scientific article

Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation

scientific article published on 07 April 2014

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia.

scientific article

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

scientific article

Platelet senescence is regulated by an internal timer, not damage inflicted by hits

scientific article published on 7 June 2010

Platelets disrupt vasculogenic mimicry by cancer cells

scientific article published on 03 April 2020

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

scientific article

Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease

scientific article published on 24 January 2013

Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases

scientific article published on 14 October 2020

Regulation of platelet lifespan by apoptosis

scientific article

Regulation of platelet membrane protein shedding in health and disease

scientific article

Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma

scientific article published on 13 June 2020

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

scientific article

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments

scientific article

The origin and function of platelet glycosyltransferases ⬇️

scientific article published on May 21, 2012

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function.

scientific article published on 22 April 2009

List of works by Emma C Josefsson

-methyl-d-aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

A model for studying the hemostatic consumption or destruction of platelets

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia

Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage

Dual roles for hepatic lectin receptors in the clearance of chilled platelets

Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.

Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia.

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

Platelet senescence is regulated by an internal timer, not damage inflicted by hits

Platelets disrupt vasculogenic mimicry by cancer cells

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease

Regulation of Platelet Production and Life Span: Role of Bcl-xL and Potential Implications for Human Platelet Diseases

Regulation of platelet lifespan by apoptosis

Regulation of platelet membrane protein shedding in health and disease

Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma

The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments

The origin and function of platelet glycosyltransferases ⬇️

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function.