List of works - Vicki Huff

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

scientific article published on 21 August 2017

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

scientific article published in PLoS ONE

Bilateral gonadoblastoma with dysgerminoma and pilocytic astrocytoma with WT1 GT-IVS9 mutation: A 46 XY phenotypic female with Frasier syndrome

scientific article published in December 2009

Characterization of a Wilms tumor in a 9-year-old girl with trisomy 18

scientific article published on 01 August 2003

Characterization of the inflammatory microenvironment and identification of potential therapeutic targets in wilms tumors

scientific article

Children's Oncology Group's 2013 blueprint for research: renal tumors

scientific article

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study ⬇️

scientific article published on August 1, 2012

Familial Wilms tumor

scientific article published in August 2004

Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors

scientific article published on 01 June 2005

Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

scientific article published on 13 November 2015

Knock-in of the R394W mutation causes MDS and cooperates with to drive aggressive myeloid neoplasms in mice

Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis

scientific article published on 12 March 2013

Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5.

scientific article

Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562.

scientific article

Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group

scientific article

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

scientific article

Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study

scientific article published on 02 July 2012

Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using 18F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth ⬇️

scientific article published on April 1, 2013

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

scientific article published on February 2016

Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens

scientific article

Rare variant detection using family-based sequencing analysis ⬇️

scientific article published on February 20, 2013

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

scientific article published on February 2015

Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

scientific article

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group.

scientific article

The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans ⬇️

scientific article published on January 1, 2013

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

scholarly article

The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome

scientific article

Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: a report from the National Wilms Tumor Study Group

scientific article published in May 2007

Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group

scientific article

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development

scientific article published on 01 June 2004

Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

scientific article published on 02 January 2013

Universal nephroblastomatosis with bilateral hyperplastic nephromegaly in siblings

scientific article published on 14 February 2008

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

scientific article

WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study

scientific article

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

scientific article

Wilms tumor genetics: a new, UnX-pected twist to the story

scientific article published on 01 February 2007

Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

scientific article

Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk

scientific article

Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene ⬇️

scientific article published on January 20, 2011

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

scientific article

Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression.

scientific article published on 25 November 2016

Wt1 functions in ovarian follicle development by regulating granulosa cell differentiation

scientific article published on 5 September 2013

Wt1 negatively regulates beta-catenin signaling during testis development

scientific article

β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma

scientific article

List of works by Vicki Huff

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

Bilateral gonadoblastoma with dysgerminoma and pilocytic astrocytoma with WT1 GT-IVS9 mutation: A 46 XY phenotypic female with Frasier syndrome

Characterization of a Wilms tumor in a 9-year-old girl with trisomy 18

Characterization of the inflammatory microenvironment and identification of potential therapeutic targets in wilms tumors

Children's Oncology Group's 2013 blueprint for research: renal tumors

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study ⬇️

Familial Wilms tumor

Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors

Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

Knock-in of the R394W mutation causes MDS and cooperates with to drive aggressive myeloid neoplasms in mice

Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis

Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5.

Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562.

Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study

Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using 18F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth ⬇️

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens

Rare variant detection using family-based sequencing analysis ⬇️

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group.

The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans ⬇️

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome

Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: a report from the National Wilms Tumor Study Group

Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development

Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

Universal nephroblastomatosis with bilateral hyperplastic nephromegaly in siblings

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

Wilms tumor genetics: a new, UnX-pected twist to the story

Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk

Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene ⬇️

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression.

Wt1 functions in ovarian follicle development by regulating granulosa cell differentiation

Wt1 negatively regulates beta-catenin signaling during testis development

β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma